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Escherichia coli is a motile bacterium that moves up a chemoattractant gradient by performing a biased random walk composed of alternating runs and tumbles. Previous models of run and tumble chemotaxis neglect one or more features of the…

定量方法 · 定量生物学 2007-06-26 J. T. Locsei

Social interaction between microbes can be described at many levels of details, ranging from the biochemistry of cell-cell interactions to the ecological dynamics of populations. Choosing the best level to model microbial communities…

种群与进化 · 定量生物学 2020-09-09 Chen Liao , Tong Wang , Sergei Maslov , Joao B. Xavier

Cellular metabolism, the integrated interconversion of thousands of metabolic substrates through enzyme-catalyzed biochemical reactions, is the most investigated complex intercellular web of molecular interactions. While the topological…

分子网络 · 定量生物学 2015-06-26 E. Almaas , B. Kovacs , T. Vicsek , Z. N. Oltvai , A. -L. Barabasi

Light scattering by small particles is one of the most prevailing and non-invasive technique for examining the properties of particulate systems chiefly of biological origin. The sub-micron particles including the bio-particles were so…

Bacteria seem masters of chemotaxis, yet recent work suggests otherwise. Henry Mattingly and colleagues (Nature Physics, 2026) argue that Escherichia coli uses only a small fraction of the sensory information available at its surface,…

细胞行为 · 定量生物学 2026-01-16 Robert G. Endres

In Escherichia coli the response to DNA damage shows strong cell-to-cell-heterogenity. This results in a random delay in cell division and asymmetrical binary fission of single cells, which can compromise the size homeostasis of the…

定量方法 · 定量生物学 2024-09-27 Ignacio Madrid Canales , James Broughton , Sylvie Méléard , Meriem El Karoui

Bacteria in bulk fluids swim collectively and display fascinating emergent dynamics. Although bacterial collective swimming in three-dimensional (3D) geometries has been well studied, its counterpart in confined two-dimensional (2D)…

软凝聚态物质 · 物理学 2021-11-16 Dipanjan Ghosh , Xiang Cheng

In nature, microorganisms must often cope with hostile environmental conditions. To do so they have developed sophisticated cooperative behavior and intricate communication capabilities, such as: direct cell-cell physical interactions via…

凝聚态物理 · 物理学 2007-05-23 Eshel Ben-Jacob , Inon Cohen , Ido Golding , Yonathan Kozlovsky

Bacterial contamination of biological conducts, catheters or water resources is a major threat to public health and can be amplified by the ability of bacteria to swim upstream. The mechanisms of this rheotaxis, the reorientation with…

软凝聚态物质 · 物理学 2019-08-12 Arnold Mathijssen , Nuris Figueroa-Morales , Gaspard Junot , Eric Clement , Anke Lindner , Andreas Zöttl

Unsafe drinking water remains a major public health concern globally, particularly in low-resource regions where routine microbiological surveillance is limited. Although Escherichia coli is the internationally recognized indicator of fecal…

机器学习 · 计算机科学 2026-04-07 Suzan Kagan , Shira Spigelman , Sankar Sudhir , Thalappil Pradeep , Hadas Mamane

Diet plays a crucial role in health, and understanding the causal effects of dietary patterns is essential for informing public health policy and personalized nutrition strategies. However, causal inference in nutritional epidemiology faces…

统计方法学 · 统计学 2026-01-26 Dafne Zorzetto , Zizhao Xie , Julian Stamp , Arman Oganisian , Roberta De Vito

A review of recent investigations into pathogenesis of psoriasis summarizing data on the relationship between the presence beta-streptococci in the organism and the cutaneous immune reaction. Results of the studies on gastrointestinal…

组织与器官 · 定量生物学 2011-10-14 Nikolai Korotky , Mikhail Peslyak

Isogenic Escherichia coli growing exponentially in a constant environment display large variation in growth-rates, division-sizes and generation-times. It is unclear how these seemingly random cell cycles can be reconciled with the precise…

定量方法 · 定量生物学 2015-10-14 Mats Wallden , David Fange , Özden Baltekin , Johan Elf

A review of recent investigations into pathogenesis of psoriasis summarizing data on the relationship between the presence {\beta}-streptococci in the organism and the cutaneous immune reaction. Results of the studies on gastrointestinal…

组织与器官 · 定量生物学 2011-10-04 Nikolai Korotky , Mikhail Peslyak

We study chemotaxis of a single {\sl E.coli} bacterium in a medium where the nutrient chemical is also undergoing diffusion and its concentration has the form of a Gaussian whose width increases with time. We measure the average first…

细胞行为 · 定量生物学 2015-04-30 Subrata Dev , Sakuntala Chatterjee

In this work, a machine learning approach for identifying the multi-omics metabolic regulatory control circuits inside the pathways is described. Therefore, the identification of bacterial metabolic pathways that are more regulated than…

分子网络 · 定量生物学 2024-04-09 Francesco Bardozzo , Pietro Lio' , Roberto Tagliaferri

Microbiome omics data including 16S rRNA reveal intriguing dynamic associations between the human microbiome and various disease states. Drastic changes in microbiota can be associated with factors like diet, hormonal cycles, diseases, and…

统计方法学 · 统计学 2024-01-09 Paramahansa Pramanik , Arnab Kumar Maity

In the growth of bacterial colonies, a great variety of complex patterns are observed in experiments, depending on external conditions and the bacterial species. Typically, existing models employ systems of reaction-diffusion equations or…

生物物理 · 物理学 2019-11-12 Lautaro Vassallo , David Hansmann , Lidia A. Braunstein

A multicomponent multiphase reactive transport simulator has been developed to facilitate the investigation of a large variety of phenomena in porous media including component transport, diffusion, microbiological growth and decay, cell…

计算工程、金融与科学 · 计算机科学 2014-10-24 Pavel Hron , Daniel Jost , Peter Bastian , Claudia Gallert , Josef Winter , Olaf Ippisch

After swallowing a liquid or a semi-liquid food product, a thin film responsible for the dynamic profile of aroma release coats the pharyngeal mucosa. The objective of the present article was to understand and quantify physical mechanisms…