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Microbiome `omics approaches can reveal intriguing relationships between the human microbiome and certain disease states. Along with the identification of specific bacteria taxa associated with diseases, recent scientific advancements…

应用统计 · 统计学 2019-10-07 Shuang Jiang , Guanghua Xiao , Andrew Y. Koh , Qiwei Li , Xiaowei Zhan

Randomized controlled trials generate experimental variation that can credibly identify causal effects, but often suffer from limited scale, while observational datasets are large, but often violate desired identification assumptions. To…

计量经济学 · 经济学 2023-12-27 George Z. Gui

Assessment of replicability is critical to ensure the quality and rigor of scientific research. In this paper, we discuss inference and modeling principles for replicability assessment. Targeting distinct application scenarios, we propose…

统计方法学 · 统计学 2021-05-11 Yi Zhao , Xiaoquan Wen

Randomization inference is a widely-used and appealing approach for analyzing treatment effects in randomized experiments, as it is finite-sample valid and does not require any distributional assumptions. However, naive application of…

计量经济学 · 经济学 2026-05-12 Xinran Li , Peizan Sheng , Zeyang Yu

The arithmetic mean plays a central role in science and technology, being directly related to the concepts of statistical expectance and centrality. Yet, it is highly susceptible to the presence of outliers or biased interference in the…

数据分析、统计与概率 · 物理学 2024-10-16 Gonzalo Travieso , Luciando da F. Costa

Kinship verification is a well-explored task: identifying whether or not two persons are kin. In contrast, kinship identification has been largely ignored so far. Kinship identification aims to further identify the particular type of…

计算机视觉与模式识别 · 计算机科学 2020-08-25 Wei Wang , Shaodi You , Sezer Karaoglu , Theo Gevers

The authors propose a robust semi-parametric empirical likelihood method to integrate all available information from multiple samples with a common center of measurements. Two different sets of estimating equations are used to improve the…

统计方法学 · 统计学 2012-10-03 Hsiao-Hsuan Wang , Yuehua Wu , Yuejiao Fu , Xiaogang Wang

This paper discusses estimation and limited information goodness-of-fit test statistics in factor models for binary data using pairwise likelihood estimation and sampling weights. The paper extends the applicability of pairwise likelihood…

统计方法学 · 统计学 2026-03-30 Haziq Jamil , Irini Moustaki , Chris Skinner

Quantification is the supervised learning task that consists of training predictors of the class prevalence values of sets of unlabelled data, and is of special interest when the labelled data on which the predictor has been trained and the…

机器学习 · 计算机科学 2023-10-10 Pablo González , Alejandro Moreo , Fabrizio Sebastiani

Assessing whether two patient populations exhibit comparable event dynamics is essential for evaluating treatment equivalence, pooling data across cohorts, or comparing clinical pathways across hospitals or strategies. We introduce a…

统计方法学 · 统计学 2026-04-10 Zoe Kristin Lange , Maryam Farhadizadeh , Holger Dette , Nadine Binder

Comparing composite models for multi-component observational data is a prevalent scientific challenge. When fitting composite models, there exists the potential for systematics from a poor fit of one model component to be absorbed by…

Existing metrics in competing risks survival analysis such as concordance and accuracy do not evaluate a model's ability to jointly predict the event type and the event time. To address these limitations, we propose a new metric, which we…

统计方法学 · 统计学 2019-08-20 Kartik Ahuja , Mihaela van der Schaar

Joint modeling has become increasingly popular for characterizing the association between one or more longitudinal biomarkers and competing risks time-to-event outcomes. However, semiparametric multivariate joint modeling for large-scale…

统计方法学 · 统计学 2025-06-17 Shanpeng Li , Emily Ouyang , Jin Zhou , Xinping Cui , Gang Li

Ecological studies involving counts of abundance, presence-absence or occupancy rates often produce data having a substantial proportion of zeros. Furthermore, these types of processes are typically multivariate and only adequately…

统计方法学 · 统计学 2011-05-17 Ali Arab , Scott H. Holan , Christopher K. Wikle , Mark L. Wildhaber

Predictive values are measures of the clinical accuracy of a binary diagnostic test, and depend on the sensitivity and the specificity of the test and on the disease prevalence among the population being studied. This article studies…

其他统计学 · 统计学 2024-08-14 Jose Antonio Roldan-Nofuentes

The following zero-sum game between nature and a statistician blends Bayesian methods with frequentist methods such as p-values and confidence intervals. Nature chooses a posterior distribution consistent with a set of possible priors. At…

统计方法学 · 统计学 2011-07-19 David R. Bickel

Electronic health record (EHR)-linked biobank data hold tremendous promise for large-scale discoveries via genome-wide association study (GWAS) on diverse phenotypic traits and biomarkers routinely captured in the EHR. However,…

应用统计 · 统计学 2026-04-14 Xingran Chen , Cheng-Han Yang , Zhenke Wu , Bhramar Mukherjee

Although randomized experiments are widely regarded as the gold standard for estimating causal effects, missing data of the pretreatment covariates makes it challenging to estimate the subgroup causal effects. When the missing data…

统计理论 · 数学 2014-01-08 Peng Ding , Zhi Geng

The statistical problem of using an initial sample to estimate the number of species in a larger sample has found important applications in fields far removed from ecology. Here we address the general problem of estimating the number of…

统计方法学 · 统计学 2018-05-16 Chao Deng , Timothy Daley , Peter Calabrese , Jie Ren , Andrew D. Smith

In the context of the widely used competing risks set-up we discuss different inference procedures for testing equality of two cumulative incidence functions, where the data may be subject to independent right-censoring or left-truncation.…

统计理论 · 数学 2015-10-13 Dennis Dobler , Markus Pauly
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