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Phylogenetic inference, the task of reconstructing how related sequences evolved from common ancestors, is a central objective in evolutionary genomics. The current state-of-the-art methods exploit probabilistic models of sequence evolution…

种群与进化 · 定量生物学 2026-02-19 Luc Blassel , Noémie Sauvage , Pierre Barrat-Charlaix , Bastien Boussau , Nicolas Lartillot , Laurent Jacob

Phylogenetic trees are frequently used to model evolution. Such trees are typically reconstructed from data like DNA, RNA, or protein alignments using methods based on criteria like maximum parsimony (amongst others). Maximum parsimony has…

种群与进化 · 定量生物学 2023-07-31 Mirko Wilde , Mareike Fischer

Phylogenetic networks are a generalization of phylogenetic trees allowing for the representation of non-treelike evolutionary events such as hybridization. Typically, such networks have been analyzed based on their `level', i.e. based on…

种群与进化 · 定量生物学 2020-05-11 Mareike Fischer , Michelle Galla , Lina Herbst , Yangjing Long , Kristina Wicke

Each gene has its own evolutionary history which can substantially differ from the evolutionary histories of other genes. For example, some individual genes or operons can be affected by specific horizontal gene transfer and recombination…

种群与进化 · 定量生物学 2022-05-26 Nadia Tahiri , Bernard Fichet , Vladimir Makarenkov

Phylogenetic tree inference using deep DNA sequencing is reshaping our understanding of rapidly evolving systems, such as the within-host battle between viruses and the immune system. Densely sampled phylogenetic trees can contain special…

种群与进化 · 定量生物学 2020-06-03 Cheng Zhang , Vu Dinh , Frederick A. Matsen

Phylogenetic networks are a type of directed acyclic graph that represent how a set $X$ of present-day species are descended from a common ancestor by processes of speciation and reticulate evolution. In the absence of reticulate evolution,…

组合数学 · 数学 2017-08-11 Andrew Francis , Charles Semple , Mike Steel

Rooted phylogenetic networks provide a more complete representation of the ancestral relationship between species than phylogenetic trees when reticulate evolutionary processes are at play. One way to reconstruct a phylogenetic network is…

组合数学 · 数学 2020-12-02 Allan Bai , Peter Erdos , Charles Semple , Mike Steel

We study maximal clades in random phylogenetic trees with the Yule-Harding model or, equivalently, in binary search trees. We use probabilistic methods to reprove and extend earlier results on moment asymptotics and asymptotic normality. In…

概率论 · 数学 2014-08-28 Svante Janson

In this paper, we use the H2 norm associated with a communication graph to characterize the robustness of consensus to noise. In particular, we restrict our attention to trees and by systematic attention to the effect of local changes in…

最优化与控制 · 数学 2011-06-21 George Forrest Young , Luca Scardovi , Naomi Ehrich Leonard

The set of nonnegative integer lattice points in a polytope, also known as the fiber of a linear map, makes an appearance in several applications including optimization and statistics. We address the problem of sampling from this set using…

统计计算 · 统计学 2024-07-24 Miles Bakenhus , Sonja Petrović

This paper introduces the order-theoretic concept of lattices along with the concept of consistent quantification where lattice elements are mapped to real numbers in such a way that preserves some aspect of the order-theoretic structure.…

计算机科学中的逻辑 · 计算机科学 2018-07-23 Kevin H. Knuth

As researchers collect increasingly large molecular data sets to reconstruct the Tree of Life, the heterogeneity of signals in the genomes of diverse organisms poses challenges for traditional phylogenetic analysis. A class of phylogenetic…

种群与进化 · 定量生物学 2015-09-11 Liang Liu , Zhenxiang Xi , Shaoyuan Wu , Charles Davis , Scott V. Edwards

A phylogenetic tree is a way to organize a finite set of species, individuals or other sources of related data. The species for which we have existing DNA data make up the set of leaves of the tree. The balanced minimal evolution method of…

组合数学 · 数学 2016-08-05 Stefan Forcey , Logan Keefe , William Sands

Classification of gene trees is an important task both in the analysis of multi-locus phylogenetic data, and assessment of the convergence of Markov Chain Monte Carlo (MCMC) analyses used in Bayesian phylogenetic tree reconstruction. The…

组合数学 · 数学 2024-06-10 Georgios Aliatimis , Ruriko Yoshida , Burak Boyaci , James A. Grant

We consider a size-structured aggregation and growth model of phytoplankton community proposed by Ackleh and Fitzpatrick [2]. The model accounts for basic biological phenomena in phytoplankton community such as growth, gravitational…

动力系统 · 数学 2015-02-11 Inom Mirzaev , David M. Bortz

The algebraic properties of flattenings and subflattenings provide direct methods for identifying edges in the true phylogeny -- and by extension the complete tree -- using pattern counts from a sequence alignment. The relatively small…

种群与进化 · 定量生物学 2022-05-06 Joshua Stevenson , Barbara Holland , Michael Charleston , Jeremy Sumner

The amount of completely sequenced chloroplast genomes increases rapidly every day, leading to the possibility to build large scale phylogenetic trees of plant species. Considering a subset of close plant species defined according to their…

The reconstruction of a central tendency `species tree' from a large number of conflicting gene trees is a central problem in systematic biology. Moreover, it becomes particularly problematic when taxon coverage is patchy, so that not all…

种群与进化 · 定量生物学 2014-05-27 Mike Steel , Joel D. Velasco

Consensus maximization is widely used for robust fitting in computer vision. However, solving it exactly, i.e., finding the globally optimal solution, is intractable. A* tree search, which has been shown to be fixed-parameter tractable, is…

计算机视觉与模式识别 · 计算机科学 2019-08-27 Zhipeng Cai , Tat-Jun Chin , Vladlen Koltun

This work presents a novel lattice-based methodology for incorporating multidimensional constraints into continuous decision variables within a genetic algorithm (GA) framework. The proposed approach consolidates established transcription…

神经与进化计算 · 计算机科学 2024-10-17 Cameron D. Harris , Kevin B. Schroeder , Jonathan Black