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The discovery of Paranthropus deyiremeda in 3.3-3.5 million year old fossil sites in Afar, together with 30% of the gorilla genome showing lineage sorting between humans and chimpanzees, and a NUMT ("nuclear mitochondrial DNA segment") on…

其他定量生物学 · 定量生物学 2018-10-12 Johan Nygren

Comparisons of DNA sequences between Neandertals and present-day humans have shown that Neandertals share more genetic variants with non-Africans than with Africans. This could be due to interbreeding between Neandertals and modern humans…

种群与进化 · 定量生物学 2012-08-13 Sriram Sankararaman , Nick Patterson , Heng Li , Svante Pääbo , David Reich

A range of a priori hypotheses about the evolution of modern and archaic genomes are further evaluated and tested. In addition to the well-known splits/introgressions involving Neanderthal genes into out-of- Africa people, or Denisovan…

种群与进化 · 定量生物学 2013-12-31 Peter J. Waddell

Our view of the universe of genomic regions harboring various types of candidate human-specific regulatory sequences (HSRS) has been markedly expanded in recent years. To infer the evolutionary origins of loci harboring HSRS, analyses of…

基因组学 · 定量生物学 2025-12-30 Gennadi Glinsky

Expansion of the neocortex is a hallmark of human evolution. However, it remains an open question what adaptive mechanisms facilitated its expansion. Here we show, using gyrencephaly index (GI) and other physiological and life-history data…

种群与进化 · 定量生物学 2015-08-26 Eric Lewitus , Iva Kelava , Alex T. Kalinka , Pavel Tomancak , Wieland B Huttner

Introgressions from Neanderthals and Denisovans were detected in modern humans. Introgressions from other archaic hominins were also implicated, however, identification of which poses a great technical challenge. Here, we introduced an…

种群与进化 · 定量生物学 2014-05-01 Ya Hu , Yi Wang , Qiliang Ding , Yungang He , Minxian Wang , Jiucun Wang , Shuhua Xu , Li Jin

Divergence time estimation requires the reconciliation of two major sources of data. These are fossil and/or biogeographic evidence that give estimates of the absolute age of nodes (ancestors) and molecular estimates that give us estimates…

种群与进化 · 定量生物学 2008-12-31 Peter J Waddell

All non-human great apes are endangered in the wild, and it is therefore important to gain an understanding of their demography and genetic diversity. To date, however, genetic studies within these species have largely been confined to…

种群与进化 · 定量生物学 2015-06-12 Aylwyn Scally , Bryndis Yngvadottir , Yali Xue , Qasim Ayub , Richard Durbin , Chris Tyler-Smith

The theory of evolution states that the diversity of species can be explained by descent with modification. Therefore, all living beings are related through a common ancestor. This evolutionary process must have left traces in our molecular…

定量方法 · 定量生物学 2018-08-09 Patricio Maturana Russel

The last few million years on planet Earth have witnessed two remarkable phases of hominid development, starting with a phase of biological evolution characterised by rather rapid increase of the size of the brain. This has been followed by…

种群与进化 · 定量生物学 2015-05-20 Brandon Carter

We consider a large population of asexually reproducing individuals in absence of selective pressure. The population size is maintained constant by the environment. We find out that distances between individuals (time from the last common…

统计力学 · 物理学 2007-05-23 Maurizio Serva

Recent studies have shown that hybridization between modern and archaic humans was commonplace in the history of our species. After admixture, some individuals with admixed autosomes carried the modern Homo Sapiens uniparental DNAs, while…

其他定量生物学 · 定量生物学 2020-03-31 Hongyao Chen , Shi Huang

Humans and chimpanzees are believed to have shared a common ancestor about 6 million years ago. Here using a new distance measure called the Jump distance, we calculate the number of base substitutions that might have occurred in the…

种群与进化 · 定量生物学 2010-02-24 Viswanath C Narayanan

Gene duplication is a major mechanism through which new genetic material is generated. Although numerous methods have been developed to differentiate the ortholog and paralogs, very few differentiate the "Parent-Daughter" relationship among…

种群与进化 · 定量生物学 2018-05-24 Haiming Tang , Angela Wilkins

Chromosomal rearrangements, which shuffle DNA throughout the genome, are an important source of divergence across taxa. Using a paired-end read approach with Illumina sequence data for archaic humans, I identify changes in genome structure…

基因组学 · 定量生物学 2015-10-07 Rebekah L. Rogers

Salamanders (urodela) have among the largest vertebrate genomes, ranging in size from 10 to over 80 pg. The urodela are divided into ten extant families each with a characteristic range in genome size. Although changes in genome size often…

基因组学 · 定量生物学 2015-03-10 Bianca Sclavi , John Herrick

Although there has been much interest in estimating divergence and admixture from genomic data, it has proven difficult to distinguish gene flow after divergence from alternative histories involving structure in the ancestral population.…

种群与进化 · 定量生物学 2013-08-01 Konrad Lohse , Laurent A. F. Frantz

This article shows how 3D geometric morphometric data can be analyzed using newly developed distance-based evolutionary tree inference methods, with extensions to planar graphs. Application of these methods to 3D representations of the…

种群与进化 · 定量生物学 2015-01-05 Peter J. Waddell

Comparison of human and chimpanzee genomes has received much attention, because of paramount role for understanding evolutionary step distinguishing us from our closest living relative. In order to contribute to insight into Y chromosome…

基因组学 · 定量生物学 2011-10-11 Vladimir Paar , Matko Glunčić , Ivan Basar , Marija Rosandić , Petar Paar , Mislav Cvitković

When long-lived, balancing selection can lead to trans-species polymorphisms that are shared by two or more species identical by descent. In this case, the gene genealogies at the selected sites cluster by allele instead of by species and,…

种群与进化 · 定量生物学 2014-01-30 Ziyue Gao , Molly Przeworski , Guy Sella
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