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The role of pulmonary surfactant is to reduce the surface tension in the lungs and to facilitate breathing. Surfactant replacement therapy (SRT) aims at bringing a substitute by instillation into the airways, a technique that has proven to…

软凝聚态物质 · 物理学 2021-09-21 L. P. A. Thai , F. Mousseau , E. K. Oikonomou , J. -F. Berret

Biological cells utilize membranes and liquid-like droplets, known as biomolecular condensates, to structure their interior. The interaction of droplets and membranes, despite being involved in several key biological processes, is so far…

软凝聚态物质 · 物理学 2024-02-21 Marcel Mokbel , Dominic Mokbel , Susanne Liese , Christoph A. Weber , Sebastian Aland

For most finite element simulations, boundary-conforming meshes have significant advantages in terms of accuracy or efficiency. This is particularly true for complex domains. However, with increased complexity of the domain, generating a…

数值分析 · 数学 2021-04-07 Jan Helmig , Fabian Key , Marek Behr , Stefanie Elgeti

We develop a robust cut finite element method for a model of diffusion in fractured media consisting of a bulk domain with embedded cracks. The crack has its own pressure field and can cut through the bulk mesh in a very general fashion.…

数值分析 · 数学 2020-06-03 Erik Burman , Peter Hansbo , Mats G. Larson

In this work, we investigate flow topology modifications produced by a swarm of large surfactant-laden droplets released in a turbulent channel flow. Droplets have same density and viscosity of the carrier fluid, so that only surface…

流体动力学 · 物理学 2023-09-26 Giovanni Soligo , Alessio Roccon , Alfredo Soldati

We study a finite element approximation of a coupled fluid-structure interaction consisting of a three-dimensional incompressible viscous fluid governed by the unsteady Stokes equations and a two-dimensional elastic plate. To avoid the use…

数值分析 · 数学 2026-02-10 Lander Besabe , Hyesuk Lee

A Galerkin finite element method for the membrane elasticity problem on a meshed surface is constructed by using two-dimensional elements extended into three dimensions. The membrane finite element model is established using the intrinsic…

数值分析 · 数学 2012-03-16 Peter Hansbo , Mats G. Larson

This work introduces a scaffolding framework to compactly parametrise solid structures with conforming NURBS elements for isogeometric analysis. A novel formulation introduces a topological, geometrical and parametric subdivision of the…

计算几何 · 计算机科学 2022-06-10 Stefano Moriconi , Parashkev Nachev , Sebastien Ourselin , M. Jorge Cardoso

We propose a novel cut finite element method for the numerical solution of the Biot system of poroelasticity. The Biot system couples elastic deformation of a porous solid with viscous fluid flow and commonly arises on domains with complex…

数值分析 · 数学 2026-02-10 Nanna Berre , Kent-Andre Mardal , André Massing , Ivan Yotov

A microfluidic device is constructed from PDMS with a single channel having a short section that is a thin flexible membrane, in order to investigate the complex fluid-structure interaction that arises between a flowing fluid and a…

软凝聚态物质 · 物理学 2020-07-03 Debadi Chakraborty , J. Ravi Prakash , Leslie Yeo , James Friend

This paper studies a model of two-phase flow with an immersed material viscous interface and a finite element method for numerical solution of the resulting system of PDEs. The interaction between the bulk and surface media is characterized…

数值分析 · 数学 2021-06-08 Maxim Olshanskii , Annalisa Quaini , Qi Sun

In this paper we study the dynamics of a layer of incompressible viscous fluid bounded below by a rigid boundary and above by a free boundary, in the presence of a uniform gravitational field. We assume that a mass of surfactant is present…

偏微分方程分析 · 数学 2017-02-09 Ian Tice , Lei Wu

This work presents a novel numerical investigation of the dynamics of free-boundary flows of viscoelastic liquid membranes. The governing equation describes the balance of linear momentum, in which the stresses include the viscoelastic…

流体动力学 · 物理学 2022-04-12 Valeria Barra , Shawn A. Chester , Shahriar Afkhami

A mechanical model and numerical method for structural membranes implied by all isosurfaces of a level-set function in a three-dimensional bulk domain are proposed. The mechanical model covers large displacements in the context of the…

计算工程、金融与科学 · 计算机科学 2023-08-02 Thomas-Peter Fries , Michael W. Kaiser

A model for the limiting surface tension of surfactant solutions (surface tension at and above the critical micelle concentration, cmc) was developed. This model takes advantage of the equilibrium between the surfactant molecules on the…

Many lipid membrane-mediated transport processes--such as mechanically-gated channel activation and solute transport--involve structural and dynamical features on membrane thickness length scales. Most existing membrane models, however,…

软凝聚态物质 · 物理学 2025-08-29 Zachary G. Lipel , Yannick A. D. Omar , Dimitrios Fraggedakis

Using numerical simulations, we investigate the effects of Marangoni stresses induced by surfactants on the effective slip length of liquid-infused surfaces (LIS) with transverse grooves. The surfactants are assumed soluble in the external…

流体动力学 · 物理学 2022-11-09 Johan Sundin , Shervin Bagheri

Computational modelling offers a cost-effective and time-efficient alternative to experimental studies in biomedical engineering. In cardiac electro-mechanics, finite element method (FEM)-based simulations provide valuable insights into…

计算工程、金融与科学 · 计算机科学 2025-08-20 Tan Tran , Denisa Martonova , Sigrid Leyendecker

A unified fluid-structure interaction (FSI) formulation is presented for solid, liquid and mixed membranes. Nonlinear finite elements (FE) and the generalized-alpha scheme are used for the spatial and temporal discretization. The membrane…

计算物理 · 物理学 2018-12-31 Roger A. Sauer , Tobias Luginsland

We develop a finite element method for a large deformation membrane elasticity problem on meshed surfaces using a tangential differential calculus approach that avoids the use of classical differential geometric methods. The method is also…

数值分析 · 数学 2014-10-30 Peter Hansbo , Mats G. Larson , Fredrik Larsson