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Tests for proportional hazards assumption concerning specified covariates or groups of covariates are proposed. The class of alternatives is wide: log-hazard rates under different values of covariates may cross, approach, go away. The data…

统计理论 · 数学 2020-01-20 Vilijandas Bagdonavičius , Rūta Levulienė

In high-stakes settings where machine learning models are used to automate decision-making about individuals, the presence of algorithmic bias can exacerbate systemic harm to certain subgroups of people. These biases often stem from the…

机器学习 · 计算机科学 2026-04-07 Erin Tan , Judy Hanwen Shen , Irene Y. Chen

Algorithms for constraint-based causal discovery select graphical causal models among a space of possible candidates (e.g., all directed acyclic graphs) by executing a sequence of conditional independence tests. These may be used to inform…

统计方法学 · 统计学 2025-09-19 Ting-Hsuan Chang , Zijian Guo , Daniel Malinsky

Inferring the effect of interventions within complex systems is a fundamental problem of statistics. A widely studied approach employs structural causal models that postulate noisy functional relations among a set of interacting variables.…

统计方法学 · 统计学 2024-02-14 David Strieder , Mathias Drton

In many observational studies in social science and medicine, subjects or units are connected, and one unit's treatment and attributes may affect another's treatment and outcome, violating the stable unit treatment value assumption (SUTVA)…

统计方法学 · 统计学 2024-06-25 Zhaonan Qu , Ruoxuan Xiong , Jizhou Liu , Guido Imbens

Hansen (1982) proposed a class of "generalized method of moments" (GMMs) for estimating a vector of regression parameters from a set of score functions. Hansen established that, under certain regularity conditions, the estimator based on…

统计理论 · 数学 2007-06-13 Ramani S. Pilla , Catherine Loader

This paper proposes a new test for the comparison of conditional quantile curves when the outcome of interest, typically a duration, is subject to right censoring. The test can be applied both in the case of two independent samples and for…

统计方法学 · 统计学 2023-02-08 Lorenzo Tedesco , Ingrid Van Keilegom

Causal inference studies whether the presence of a variable influences an observed outcome. As measured by quantities such as the "average treatment effect," this paradigm is employed across numerous biological fields, from vaccine and drug…

Competing risk data appear widely in modern biomedical research. Cause-specific hazard models are often used to deal with competing risk data in the past two decades. There is no current study on the kernel likelihood method for the…

统计方法学 · 统计学 2021-09-14 Xiaomeng Qi , Zhangsheng Yu

Refined vaccine regimens containing variant-matched inserts are often authorized based on historical phase 3 efficacy trials together with immunobridging studies. Phase 3 trials are essential for establishing immune biomarkers that reliably…

统计方法学 · 统计学 2026-04-16 Pan Zhao , Peter B. Gilbert , Oliver Dukes , Bo Zhang

The primary analysis in two-arm clinical trials usually involves inference on a scalar treatment effect parameter; e.g., depending on the outcome, the difference of treatment-specific means, risk difference, risk ratio, or odds ratio. Most…

统计方法学 · 统计学 2022-04-25 Anastasios A. Tsiatis , Marie Davidian

Survival analysis is a widely known method for predicting the likelihood of an event over time. The challenge of dealing with censored samples still remains. Traditional methods, such as the Cox Proportional Hazards (CPH) model, hinge on…

机器学习 · 计算机科学 2025-01-10 Chanon Puttanawarut , Panu Looareesuwan , Romen Samuel Wabina , Prut Saowaprut

Balanced representation learning methods have been applied successfully to counterfactual inference from observational data. However, approaches that account for survival outcomes are relatively limited. Survival data are frequently…

We study a new model where the potential outcomes, corresponding to the values of a (possibly continuous) treatment, are linked through common factors. The factors can be estimated using a panel of regressors. We propose a procedure to…

计量经济学 · 经济学 2024-01-09 Jad Beyhum

This paper studies inference in randomized controlled trials with covariate-adaptive randomization when there are multiple treatments. More specifically, we study inference about the average effect of one or more treatments relative to…

计量经济学 · 经济学 2019-01-21 Federico A. Bugni , Ivan A. Canay , Azeem M. Shaikh

This article develops new closed-form variance expressions for power analyses for commonly used difference-in-differences (DID) and comparative interrupted time series (CITS) panel data estimators. The main contribution is to incorporate…

统计方法学 · 统计学 2021-10-18 Peter Z. Schochet

Along with the increasing availability of health data has come the rise of data-driven models to inform decision-making and policy. These models have the potential to benefit both patients and health care providers but can also exacerbate…

统计方法学 · 统计学 2023-10-16 Solvejg Wastvedt , Jared Huling , Julian Wolfson

This study considers various semiparametric difference-in-differences models under different assumptions on the relation between the treatment group identifier, time and covariates for cross-sectional and panel data. The variance lower…

计量经济学 · 经济学 2020-08-17 Michael Zimmert

In a randomised clinical trial, when the result of the primary endpoint shows a significant benefit, the secondary endpoints are scrutinised to identify additional effects of the treatment. However, this approach entails a risk of…

We propose new simultaneous inference methods for diagnostic trials with elaborate factorial designs. Instead of the commonly used total area under the receiver operating characteristic (ROC) curve, our parameters of interest are partial…

统计理论 · 数学 2023-02-22 Maximilian Wechsung , Frank Konietschke