相关论文: Analysis of Heterogeneous Cardiac Pacemaker Tissue…
Biological cells are built up from many different constituents of varying size and stiffness which all contribute to the cell's mechanical properties. Despite this heterogeneity, in the analysis of experimental measurements such as atomic…
Systems of dynamical elements exhibiting spontaneous rhythms are found in various fields of science and engineering, including physics, chemistry, biology, physiology, and mechanical and electrical engineering. Such dynamical elements are…
We present Cardiac Stability Theory (CST), an axiomatically grounded framework formally defining cardiovascular health as a stability margin around a cardiac dynamical attractor. From four axioms we derive the Cardiac Stability Index (CSI),…
Biological foundation models have shown strong performance in single-cell representation learning by applying transformer architectures directly to gene-expression matrices. However, these approaches predominantly operate in static settings…
This paper presents a nonlinear reaction-diffusion-fluid system that simulates radiofrequency ablation within cardiac tissue. The model conveys the dynamic evolution of temperature and electric potential in both the fluid and solid regions,…
Convolutional neural networks (CNN) have demonstrated their ability to segment 2D cardiac ultrasound images. However, despite recent successes according to which the intra-observer variability on end-diastole and end-systole images has been…
Phasor Agents are dynamical systems whose internal state is a Phasor Graph: a weighted graph of coupled Stuart-Landau oscillators. A Stuart-Landau oscillator is a minimal stable "rhythm generator" (the normal form near a Hopf bifurcation);…
The lattice gas model of condensation in a heterogeneous pore system, represented by a random graph of cells, is studied using an exact analytical solution. A binary mixture of pore cells with different coordination numbers is shown to…
We generalize the Cable Model to describe the transport characteristics of the gap junctions coupling adjacent cells in the heart muscle. Our model takes into account recent experimental information about the time dependence of the…
We analyze the structure and stickiness in the chaotic components of generic Hamiltonian systems with divided phase space. Following the method proposed recently in Lozej and Robnik [Phys. Rev. E 98, 022220 (2018)], the sticky regions are…
The CVS is composed of numerous interacting and dynamically regulated physiological subsystems which each generate measurable periodic components such that the CVS can itself be presented as a system of weakly coupled oscillators. The…
With superiorities on low cost, portability, and free of radiation, echocardiogram is a widely used imaging modality for left ventricle (LV) function quantification. However, automatic LV segmentation and motion tracking is still a…
Discordant alternans,the phenomenon of 2 separate cardiac tissue locations exhibiting action potential duration (APD) alternans of opposite phase, appears to be a potential mechanism for electrocardiographic T wave alternans, but its…
In this paper, we report on the generation and propagation of traveling pulses in a homogeneous network of diffusively coupled, excitable, slow-fast dynamical neurons. The spatially extended system is modelled using the nearest neighbor…
We investigate the modes of oscillation of heterogeneous ring-networks of quadratic integrate-and-fire neurons with non-local, space-dependent coupling. Perturbations of the equilibrium state with a particular wave number produce transient…
The human brain is a complex dynamical system which displays a wide range of macroscopic and mesoscopic patterns of neural activity, whose mechanistic origin remains poorly understood. Whole-brain modelling allows us to explore candidate…
Rhythmogenesis, which is critical for many biological functions, involves a transition to coherent activity through cell-cell communication. In the absence of centralized coordination by specialized cells (pacemakers), competing oscillating…
Conventional methods for diagnosing Social Anxiety Disorder (SAD), such as clinical interviews and self-reported questionnaires, often face accessibility barriers and subjective biases, underscoring the need for objective physiological…
A parasystole from a heart-transplant patient is analysed using a beat-to-beat RR interval time series obtained from an electrocardiogram (ECG). The dysrhythmia, resulting from the co-existence of two pacemakers, the sinus node and an…
We design a neural network Ansatz for variationally finding the ground-state wave function of the Homogeneous Electron Gas, a fundamental model in the physics of extended systems of interacting fermions. We study the spin-polarised and…