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Most single-molecule studies derive the kinetic rates of native, intermediate, and unfolded states from equilibrium hopping experiments. Here, we apply Kramers kinetic diffusive model to derive the force-dependent kinetic rates of…

软凝聚态物质 · 物理学 2022-04-13 Marc Rico-Pasto , Anna Alemany , Felix Ritort

We introduce an anisotropic mean-field approach for the dynamics of semiflexible polymers under intermediate tension, the force range where a chain is partially extended but not in the asymptotic regime of a nearly straight contour. The…

软凝聚态物质 · 物理学 2011-07-14 Michael Hinczewski , Roland R. Netz

This paper deals with the old and classical problem of determining necessary conditions for the overconstrained mobility of some mechanical device. In particular, we show that the mobility of pentapods/hexapods implies either a collinearity…

机器人学 · 计算机科学 2017-07-19 Matteo Gallet , Georg Nawratil , Josef Schicho

We derive and describe a very accurate variational scheme for the ground state of the system of a few ultra-cold bosons confined in one-dimensional traps of arbitrary shapes. It is based on assumption that all inter-particle correlations…

量子气体 · 物理学 2021-06-24 Przemysław Kościk , Arkadiusz Kuroś , Adam Pieprzycki , Tomasz Sowiński

Predicting the three-dimensional (3D) functional structures of proteins remains an important computational milestone in molecular biology to be achieved. This feat is hinged on a clear understanding of the mechanism which proteins use to…

生物大分子 · 定量生物学 2019-11-28 Samuel Nkrumah

Particles trapped in the evanescent field of an ultrathin optical fibre inter-act over very long distances via multiple scattering of the fibre-guided fields. In ultrathin fibres that support higher order modes, these interac-tions are…

We first argue that the covalent bond and the various closed-shell interactions can be thought of as symmetry broken versions of one and the same interaction, viz., the multi-center bond. We use specially chosen molecular units to show that…

强关联电子 · 物理学 2017-06-16 Jon C. Golden , Vinh Ho , Vassiliy Lubchenko

A trapping mechanism is observed and proposed as the origin of the anomalous behavior recently discovered in transport properties of overdamped ratchets subject to external oscillatory drive in the presence of quenched noise. In particular,…

统计力学 · 物理学 2009-11-13 D. G. Zarlenga , H. A. Larrondo , C. M. Arizmendi , F. Family

During the last decade, the laser trapping technique has been actively applied to elucidate the property of macromolecules, DNA, RNA, cytoskeleton fibres, etc. Due to the inherent difficulty in the direct trapping of single molecules at…

软凝聚态物质 · 物理学 2016-08-31 Masatoshi Ichikawa , Kenichi Yoshikawa , Yukiko Matsuzawa

We propose that several mechanisms contribute to friction in a polymer melt adsorbed at a structured surface. The first one is the well known disentanglement of bulk polymer chains from the surface layer. However, if the surface is ideal at…

软凝聚态物质 · 物理学 2007-05-23 X. Zhou , D. Andrienko , L. Delle Site , K. Kremer

The principles underlying protein folding remains one of Nature's puzzles with important practical consequences for Life. An approach that has gathered momentum since the late 1990's, looks at protein hetero-polymers and their folding…

计算工程、金融与科学 · 计算机科学 2011-10-05 Susan Khor

Loop formation between monomers in the interior of semiflexible chains describes elementary events in biomolecular folding and DNA bending. We calculate analytically the interior distance distribution function for semiflexible chains using…

软凝聚态物质 · 物理学 2009-11-11 Changbong Hyeon , D. Thirumalai

Molecular dynamics simulations were performed for a polymer melt. In quiescent states, the inter-chain interaction energy supported by each particle takes relatively large values persistently for long times if the particle is close to an…

软凝聚态物质 · 物理学 2007-05-23 Ryoichi Yamamoto , Akira Onuki

We report an experimental investigation of the caging motion in a uniformly heated granular fluid, for a wide range of filling fractions, $\phi$. At low $\phi$ the classic diffusive behavior of a fluid is observed. However, as $\phi$ is…

软凝聚态物质 · 物理学 2009-11-11 Pedro M. Reis , Rohit A. Ingale , Mark D. Shattuck

Mechanical forces acting on cell adhesion receptor proteins regulate a range of cellular functions by formation and rupture of non-covalent interactions with ligands. Typically, force decreases the lifetimes of intact complexes…

生物大分子 · 定量生物学 2014-06-16 Shaon Chakrabarti , Michael Hinczewski , D. Thirumalai

We investigate the effect of the trapping potential on the quantum phases of strongly correlated ultracold bosons in one-dimensional periodic and quasiperiodic optical lattices. By means of a decoupling meanfield approach, we characterize…

量子气体 · 物理学 2015-02-26 Uttam Shrestha , Michele Modugno

The transport coefficients of dense polymeric fluids are approximately calculated from the microscopic intermolecular forces. The following finite molecular weight effects are discussed within the Polymer-Mode-Coupling theory (PMC) and…

凝聚态物理 · 物理学 2009-10-30 Matthias Fuchs , Kenneth S. Schweizer

Pairs of free particles cannot form bound states in elastic collision due to momentum and energy conservation. In many ultracold experiments, however, the particles collide in the presence of an external trapping potential which can couple…

原子物理 · 物理学 2023-11-17 Meirav Pinkas , Or Katz , Jonathan Wengrowicz , Nitzan Akerman , Roee Ozeri

We consider a statistical mechanics model for biopolymers. Sophisticated polymer chains, such as DNA, have stiffness when they stretch chains. The Laplacian interaction is used to describe the stiffness. Also, the surface between two media…

概率论 · 数学 2014-08-05 Chien-Hao Huang

A solid-state nanopore can electrophoretically capture a DNA molecule and pull it through in a folded configuration. The resulting ionic current signal indicates where along its length the DNA was captured. A statistical study using an 8 nm…

生物物理 · 物理学 2015-06-11 Mirna Mihovilovic , Nick Hagerty , Derek Stein