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Genome-wide association analysis has generated much discussion about how to preserve power to detect signals despite the detrimental effect of multiple testing on power. We develop a weighted multiple testing procedure that facilitates the…

统计理论 · 数学 2007-06-13 Kathryn Roeder , Bernie Devlin , Larry Wasserman

We introduce a simple tool to control for false discoveries and identify individual signals in scenarios involving many tests, dependent test statistics, and potentially sparse signals. The tool applies the Cauchy combination test…

计量经济学 · 经济学 2023-06-02 Nabil Bouamara , Sébastien Laurent , Shuping Shi

This paper considers the problem of testing many moment inequalities where the number of moment inequalities, denoted by $p$, is possibly much larger than the sample size $n$. There is a variety of economic applications where solving this…

统计理论 · 数学 2018-10-22 Victor Chernozhukov , Denis Chetverikov , Kengo Kato

In MT evaluation, pairwise comparisons are conducted to identify the better system. In conducting the comparison, the experimenter must allocate a budget to collect Direct Assessment (DA) judgments. We provide a cost effective way to spend…

应用统计 · 统计学 2022-11-11 Johnny Tian-Zheng Wei , Tom Kocmi , Christian Federmann

Conditional independence testing is a key problem required by many machine learning and statistics tools. In particular, it is one way of evaluating the usefulness of some features on a supervised prediction problem. We propose a novel…

机器学习 · 统计学 2019-08-02 Marco Henrique de Almeida Inácio , Rafael Izbicki , Rafael Bassi Stern

Selective inference is a subfield of statistics that enables valid inference after selection of a data-dependent question. In this paper, we introduce selectively dominant p-values, a class of p-values that allow practitioners to easily…

统计方法学 · 统计学 2024-11-22 Anav Sood

We introduce a method for calculating \(p\)-values to test causal hypotheses in qualitative research \emph{a la} process tracing. As in an experiment, our \(p\)-value tells us how often one would make the same or more compelling…

统计方法学 · 统计学 2025-08-04 Matias Lopez , Jake Bowers

In the field of multiple hypothesis testing, combining p-values represents a fundamental statistical method. The Cauchy combination test (CCT) (Liu and Xie, 2020) excels among numerous methods for combining p-values with powerful and…

统计方法学 · 统计学 2024-10-17 Yanyan Ouyang , Xingwei Liu , Lixing Zhu , Wangli Xu

Evaluating intervention effects on multiple outcomes is a central research goal in a wide range of quantitative sciences. It is thereby common to compare interventions among each other and with a control across several, potentially highly…

Testing intersections of null-hypotheses is an integral part of closed testing procedures for assessing multiple null-hypotheses under family-wise type 1 error control. Popular intersection tests such as the minimum p-value test are based…

统计方法学 · 统计学 2025-11-11 Christian Bressen Pipper , Andreas Nordland , Klaus Kähler Holst

We present an aggregation scheme that increases power in randomized controlled trials and quasi-experiments when the intervention possesses a robust and well-articulated theory of change. Longitudinal data analyzing interventions often…

统计方法学 · 统计学 2022-07-27 Timothy Lycurgus , Ben B. Hansen

Here we propose a test to detect effects of single nucleotide polymorphisms (SNPs) on a quantitative trait. Significant SNP-SNP interactions are more difficult to detect than significant SNPs, partly due to the massive amount of SNP-SNP…

Treatment-covariate interaction tests are commonly applied by researchers to examine whether the treatment effect varies across patient subgroups defined by baseline characteristics. The objective of this study is to explore…

统计方法学 · 统计学 2024-03-12 Likun Zhang , Wei Ma

The two-trials rule in drug regulation requires statistically significant results from two pivotal trials to demonstrate efficacy. However, it is unclear how the effect estimates from both trials should be combined to quantify the drug…

统计方法学 · 统计学 2025-07-08 Samuel Pawel , Małgorzata Roos , Leonhard Held

Given a set of several inputs into a system (e.g., independent variables characterizing stimuli) and a set of several stochastically non-independent outputs (e.g., random variables describing different aspects of responses), how can one…

数据分析、统计与概率 · 物理学 2012-09-04 Ehtibar N. Dzhafarov , Janne V. Kujala

Conformal prediction methods are statistical tools designed to quantify uncertainty and generate predictive sets with guaranteed coverage probabilities. This work introduces an innovative refinement to these methods for classification…

机器学习 · 统计学 2025-12-04 Jean-Baptiste Fermanian , Mohamed Hebiri , Joseph Salmon

The multiple testing literature has primarily dealt with three types of dependence assumptions between p-values: independence, positive regression dependence, and arbitrary dependence. In this paper, we provide what we believe are the first…

统计理论 · 数学 2024-05-10 Ziyu Chi , Aaditya Ramdas , Ruodu Wang

Conformalized multiple testing offers a model-free way to control predictive uncertainty in decision-making. Existing methods typically use only part of the available data to build score functions tailored to specific settings. We propose a…

统计方法学 · 统计学 2026-05-22 Yuyang Huo , Xiaoyang Wu , Changliang Zou , Haojie Ren

The classical theory for the meta-analysis of $p$-values is based on the assumption that if the overall null hypothesis is true, then all $p$-values used in a chosen combined test statistic are genuine, i.e., are observations from…

统计计算 · 统计学 2024-10-08 Rui Santos , M. Fátima Brilhante , Sandra Mendonça

Replicability is a lynchpin for credible discoveries. The partial conjunction (PC) p-value, which combines individual base p-values from multiple similar studies, can gauge whether a feature of interest exhibits replicated signals across…

统计方法学 · 统计学 2025-07-29 Ninh Tran , Dennis Leung