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We are witnessing the birth of a new variety of pharmacokinetics where non-integer-order differential equations are employed to study the time course of drugs in the body: this is dubbed "fractional pharmacokinetics." The presence of…

This paper presents three fractional models formulated from a classical Pharmacokinetics compartmental system: commensurable, non-commensurable, and implicit non-commensurable models. Their distinguishing characteristics are further…

定量方法 · 定量生物学 2023-06-16 Reindorf Nartey Borkor , Adu Sakyi , Peter Amoako-Yirenkyi

This study investigates the use of fractional order differential models to simulate the dynamic response of non-homogeneous discrete systems and to achieve efficient and accurate model order reduction. The traditional integer order approach…

数值分析 · 数学 2016-12-22 John P. Hollkamp , Mihir Sen , Fabio Semperlotti

Fractional equations have become the model of choice in several applications where heterogeneities at the microstructure result in anomalous diffusive behavior at the macroscale. In this work we introduce a new fractional operator…

数值分析 · 数学 2021-01-29 Marta D'Elia , Christian Glusa

This contribution deals with identification of fractional-order dynamical systems. System identification, which refers to estimation of process parameters, is a necessity in control theory. Real processes are usually of fractional order as…

其他计算机科学 · 计算机科学 2016-11-15 Deepyaman Maiti , Ayan Acharya , R. Janarthanan , Amit Konar

This contribution deals with the creation of numerical models for the simulation of the dynamic characteristics of fractional-order control systems and their comparison with analytical models. We give the results of the comparison of…

最优化与控制 · 数学 2007-05-23 L. Dorcak

We present a novel method to improve pharmacokinetics modeling, an essential step of drug development. Conventional models frequently fail to fully represent the intricacies of drug absorption and distribution, which limits their predictive…

定量方法 · 定量生物学 2024-12-31 Nazanin Ahmadi , Shupeng Wang , George Karniadakis

This paper presents a data-integrated framework for learning the dynamics of fractional-order nonlinear systems in both discrete-time and continuous-time settings. The proposed framework consists of two main steps. In the first step,…

系统与控制 · 电气工程与系统科学 2025-06-19 Bahram Yaghooti , Chengyu Li , Bruno Sinopoli

This paper deals with fractional-order controlled systems and fractional-order controllers in the frequency domain. The mathematical description by fractional transfer functions and properties of these systems are presented. The new ways…

最优化与控制 · 数学 2007-05-23 I. Petras , L. Dorcak , P. O'Leary , B. M. Vinagre , I. Podlubny

Modeling of phenomena such as anomalous transport via fractional-order differential equations has been established as an effective alternative to partial differential equations, due to the inherent ability to describe large-scale behavior…

偏微分方程分析 · 数学 2021-10-25 Jorge Suzuki , Mamikon Gulian , Mohsen Zayernouri , Marta D'Elia

In this work, we introduce a new three-dimensional chaotic differential dynamical system. We find equilibrium points of this system and provide the stability conditions for various fractional orders. Numerical simulations will be used to…

混沌动力学 · 物理学 2020-07-08 Madhuri Patil , Sachin Bhalekar

This paper deals with fractional-order controlled systems and fractional-order controllers in the discrete domain. The mathematical description by the fractional difference equations and properties of these systems are presented. A…

最优化与控制 · 数学 2007-05-23 I. Petras , L. Dorcak , I. Kostial

This contribution deals with identification of fractional-order dynamical systems. System identification, which refers to estimation of process parameters, is a necessity in control theory. Real processes are usually of fractional order as…

其他计算机科学 · 计算机科学 2016-11-15 Deepyaman Maiti , Mithun Chakraborty , Amit Konar

Multi-system interaction is an important and difficult problem in physics. Motivated by the experimental result of an electronic circuit element "Fractor", we introduce the concept of dynamic-order fractional dynamic system, in which the…

数学物理 · 物理学 2013-04-10 HongGuang Sun , Hu Sheng , YangQuan Chen , Wen Chen , ZhongBo Yu

Fractional dynamics is a field of study in physics and mechanics investigating the behavior of objects and systems that are characterized by power-law non-locality, power-law long-term memory or fractal properties by using integrations and…

综合物理 · 物理学 2015-03-12 Vasily E. Tarasov

In this paper, an efficient control strategy for physiological interaction based anaesthetic drug infusion model is explored using the fractional order (FO) proportional integral derivative (PID) controllers. The dynamic model is composed…

系统与控制 · 计算机科学 2016-12-01 Saptarshi Das , Sourav Das , Koushik Maharatna

No mixed research of hybrid and fractional-order systems into a cohesive and multifaceted whole can be found in the literature. This paper focuses on such a synergistic approach of the theories of both branches, which is believed to give…

系统与控制 · 计算机科学 2014-07-25 S. Hassan HosseinNia , Ines Tejado , Blas M. Vinagre

In this paper we will present some alternative types of mathematical description and methods of solution of the fractional-order dynamical system in the state space. We point out the difference in the true sense of the name "state" space…

最优化与控制 · 数学 2007-05-23 L. Dorcak , I. Petras , I. Kostial , J. Terpak

Recent studies have demonstrated the advantages of fractional-order calculus tools for probing the viscoelastic properties of collagenous tissue, characterizing the arterial blood flow and red cell membrane mechanics, and modeling the…

系统与控制 · 电气工程与系统科学 2020-10-21 Mohamed A. Bahloul , Taous-Meriem Laleg Kirati

Identification of fractional order systems is considered from an algebraic point of view. It allows for a simultaneous estimation of model parameters and fractional (or integer) orders from input and output data. It is exact in that no…

最优化与控制 · 数学 2013-02-19 Nicole Gehring , Joachim Rudolph
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