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Understanding how cortex, subcortex and cerebellum integrate is a major challenge for neuroscience, however, studies of the brain's structural connectivity have mostly focused on cortico-cortical links. Here, we used diffusion imaging to…

神经元与认知 · 定量生物学 2025-10-21 Julian Schulte , Mario Senden , Gustavo Deco , Xenia Kobeleva , Gorka Zamora-López

Node role explainability in complex networks is very difficult, yet is crucial in different application domains such as social science, neurosciences or computer science. Many efforts have been made on the quantification of hubs revealing…

神经元与认知 · 定量生物学 2023-02-01 Lucrezia Carboni , Michel Dojat , Sophie Achard

The detailed functioning of the human brain is still poorly understood. Brain simulations are a well-established way to complement experimental research, but must contend with the computational demands of the approximately $10^{11}$ neurons…

分布式、并行与集群计算 · 计算机科学 2025-10-01 Fabian Czappa , Marvin Kaster , Felix Wolf

We introduce TempoCave, a novel visualization application for analyzing dynamic brain networks, or connectomes. TempoCave provides a range of functionality to explore metrics related to the activity patterns and modular affiliations of…

人机交互 · 计算机科学 2020-01-16 Ran Xu , Manu Mathew Thomas , Alex Leow , Olusola Ajilore , Angus G. Forbes

Functional Connectivity (FC) matrices measure the regional interactions in the brain and have been widely used in neurological brain disease classification. However, a FC matrix is neither a natural image which contains shape and texture…

医学物理 · 物理学 2020-01-10 Xiaodan Xing , Qingfeng Li , Hao Wei , Minqing Zhang , Yiqiang Zhan , Xiang Sean Zhou , Zhong Xue , Feng Shi

Brain connectomics is still largely dominated by pairwise-based models, such as graphs, which cannot represent circulatory or higher-order functional interactions. In this paper, we propose a multimodal framework based on Topological Signal…

神经元与认知 · 定量生物学 2026-04-01 Breno C. Bispo , Stefania Sardellitti , Juliano B. Lima , Fernando A. N. Santos

The brain can be regarded as a network: a connected system where nodes, or units, represent different specialized regions and links, or connections, represent communication pathways. From a functional perspective communication is coded by…

神经元与认知 · 定量生物学 2014-09-10 Fabrizio De Vico Fallani , Jonas Richiardi , Mario Chavez , Sophie Achard

This paper describes an ongoing multi-scale visual analytics approach for exploring and analyzing biomedical knowledge at scale.We utilize global and local views, hierarchical and flow-based graph layouts, multi-faceted search, neighborhood…

Purpose: The goal of this work was to develop a deep network for whole-head segmentation including clinical MRIs with abnormal anatomy, and compile the first public benchmark dataset for this purpose. We collected 98 MRIs with volumetric…

图像与视频处理 · 电气工程与系统科学 2025-09-04 Andrew M Birnbaum , Adam Buchwald , Peter Turkeltaub , Adam Jacks , George Carra , Shreya Kannana , Yu Huang , Abhisheck Datta , Lucas C Parra , Lukas A Hirsch

Brain network analysis is vital for understanding the neural interactions regarding brain structures and functions, and identifying potential biomarkers for clinical phenotypes. However, widely used brain signals such as Blood Oxygen Level…

机器学习 · 计算机科学 2024-05-02 Kaiqiao Han , Yi Yang , Zijie Huang , Xuan Kan , Yang Yang , Ying Guo , Lifang He , Liang Zhan , Yizhou Sun , Wei Wang , Carl Yang

Estimated connectomes by the means of neuroimaging techniques have enriched our knowledge of the organizational properties of the brain leading to the development of network-based clinical diagnostics. Unfortunately, to date, many of those…

神经元与认知 · 定量生物学 2018-05-31 Roseric Azondekon , Zachary James Harper , Charles Michael Welzig

We analyze functional magnetic resonance imaging (fMRI) data from the Human Connectome Project (HCP) to match brain activities during a range of cognitive tasks. Our findings demonstrate that even basic linear machine learning models can…

神经元与认知 · 定量生物学 2025-10-08 Valeriya Kirova , Dzerassa Kadieva , Daniil Vlasenko , Isak B. Blank , Fedor Ratnikov

Analyzing connections between brain regions of interest (ROI) is vital to detect neurological disorders such as autism or schizophrenia. Recent advancements employ graph neural networks (GNNs) to utilize graph structures in brains,…

机器学习 · 计算机科学 2024-01-03 Falih Gozi Febrinanto , Mujie Liu , Feng Xia

Developing a new diagnostic models based on the underlying biological mechanisms rather than subjective symptoms for psychiatric disorders is an emerging consensus. Recently, machine learning-based classifiers using functional connectivity…

信号处理 · 电气工程与系统科学 2024-10-14 Kaizhong Zheng , Shujian Yu , Baojuan Li , Robert Jenssen , Badong Chen

Gliomas are brain tumors composed of different highly heterogeneous histological subregions. Image analysis techniques to identify relevant tumor substructures have high potential for improving patient diagnosis, treatment and prognosis.…

图像与视频处理 · 电气工程与系统科学 2022-07-18 José Gerardo Suárez-García Javier Miguel Hernández-López , Eduardo Moreno-Barbosa , Benito de Celis-Alonso

Recent neuroimaging studies have shown that functional connectomes are unique to individuals, i.e., two distinct fMRIs taken over different sessions of the same subject are more similar in terms of their connectomes than those from two…

计算机视觉与模式识别 · 计算机科学 2019-08-12 Vikram Ravindra , Petros Drineas , Ananth Grama

While statistical analysis of a single network has received a lot of attention in recent years, with a focus on social networks, analysis of a sample of networks presents its own challenges which require a different set of analytic tools.…

统计方法学 · 统计学 2019-10-23 Jesús D. Arroyo-Relión , Daniel Kessler , Elizaveta Levina , Stephan F. Taylor

This paper considers the problem of brain disease classification based on connectome data. A connectome is a network representation of a human brain. The typical connectome classification problem is very challenging because of the small…

We present here a browser-based application for visualizing patterns of connectivity in 3D stacked data matrices with large numbers of pairwise relations. Visualizing a connectivity matrix, looking for trends and patterns, and dynamically…

神经元与认知 · 定量生物学 2018-01-04 David J. Caldwell , Jing Wu , Kaitlyn Casimo , Jeffrey G. Ojemann , Rajesh P. N. Rao

Exploring the human brain networks during rest is a topic of great interest. Several structural and functional studies have previously been conducted to study the intrinsic brain networks. In this paper, we focus on investigating the human…

神经元与认知 · 定量生物学 2016-07-05 Aya Kabbara , Wassim El Falou , Mohamad Khalil , Fabrice Wendling , Mahmoud Hassan