相关论文: Using Sequence Ensembles for Seeding Alignments of…

Background: Identifying all possible mapping locations of next-generation sequencing (NGS) reads is highly essential in several applications such as prediction of genomic variants or protein binding motifs located in repeat regions, isoform…

We propose a novel approach to select the best model of the data. Based on the exclusive properties of the nested models, we find the most parsimonious model containing the risk minimizer predictor. We prove the existence of probable…

Ensembling neural networks is a long-standing technique for improving the generalization error of neural networks by combining networks with orthogonal properties via a committee decision. We show that this technique is an ideal fit for…

Recent advances in learnable evolutionary algorithms have demonstrated the importance of leveraging population distribution information and historical evolutionary trajectories. While significant progress has been made in continuous…

Sequence alignments are fundamental to bioinformatics which has resulted in a variety of optimized implementations. Unfortunately, the vast majority of them are hand-tuned and specific to certain architectures and execution models. This not…

The detection of genomic structural variation (SV) has advanced tremendously in recent years due to progress in high-throughput sequencing technologies. Novel sequence insertions, insertions without similarity to a human reference genome,…

Considering a heterogeneous network (HetNet) system consisting of a macro tier overlaid with a second tier of small cells (SCs), this paper studies the mean square error (MSE) based precoding design to be employed by the macro base station…

We developed a low-cost, high-throughput microbiome profiling method that uses combinatorial sequence tags attached to PCR primers that amplify the rRNA V6 region. Amplified PCR products are sequenced using an Illumina paired-end protocol…

Preference orderings are orderings of a set of items according to the preferences (of judges). Such orderings arise in a variety of domains, including group decision making, consumer marketing, voting and machine learning. Measuring the…

Often, machine learning applications have to cope with dynamic environments where data are collected in the form of continuous data streams with potentially infinite length and transient behavior. Compared to traditional (batch) data…

In the emerging field of DNA storage, data is encoded as DNA sequences and stored. The data is read out again by sequencing the stored DNA. Nanopore sequencing is a new sequencing technology that has many advantages over other methods; in…

In sequence modeling tasks the token order matters, but this information can be partially lost due to the discretization of the sequence into data points. In this paper, we study the imbalance between the way certain token pairs are…

One of the central problems in the classification of individual test sequences (e.g. genetic analysis), is that of checking for the similarity of sample test sequences as compared with a set of much longer training sequences. This is done…

In this paper we give improved constructions of several central objects in the literature of randomness extraction and tamper-resilient cryptography. Our main results are: (1) An explicit seeded non-malleable extractor with error $\epsilon$…

This work focuses on distributed linear precoding when users transmit correlated information over a fading Multiple-Input and Multiple-Output Multiple Access Channel. Precoders are optimized in order to minimize the sum-Mean Square Error…

Labeling of DNA molecules is a fundamental technique for DNA visualization and analysis. This process was mathematically modeled in [1], where the received sequence indicates the positions of the used labels. In this work, we develop error…

Hybrid precoding design is challenging for millimeter-wave (mmWave) massive MIMO. Most prior hybrid precoding schemes are designed to maximize the sum spectral efficiency (SSE), while seldom investigate the bit-error-rate (BER). Therefore,…

Sparse reduced-rank regression is an important tool to uncover meaningful dependence structure between large numbers of predictors and responses in many big data applications such as genome-wide association studies and social media…

The application of artificial intelligence (AI) models in fields such as engineering is limited by the known difficulty of quantifying the reliability of an AI's decision. A well-calibrated AI model must correctly report its accuracy on…

When performing an analysis on a collection of molecular sequences, it can be convenient to reduce the number of sequences under consideration while maintaining some characteristic of a larger collection of sequences. For example, one may…