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During the past century, biologists and mathematicians investigated two mechanisms underlying bacteria motion: the run phase during which bacteria move in straight lines and the tumble phase in which they change their orientation. When…

偏微分方程分析 · 数学 2025-05-19 Alain Blaustein

Navigation up a sensory gradient is one of the simplest behaviours, and the simplest strategy is run and tumble. But some organisms use other strategies, such as reversing direction or turning by some angle. Here we ask what drives the…

We study a simple run-and-tumble random walk whose switching frequency from run mode to tumble mode and the reverse depend on a stochastic signal. We consider a particularly sharp, step-like dependence, where the run to tumble switching…

细胞行为 · 定量生物学 2019-01-09 Subrata Dev , Sakuntala Chatterjee

One of simplest examples of navigation found in nature is run-and-tumble chemotaxis. Tumbles reorient cells randomly, and cells can drift toward attractants or away from repellents by biasing the frequency of these events. The post-tumble…

软凝聚态物质 · 物理学 2017-09-14 Julius B. Kirkegaard , Raymond E. Goldstein

Inputs to signaling pathways can have complex statistics that depend on the environment and on the behavioral response to previous stimuli. Such behavioral feedback is particularly important in navigation. Successful navigation relies on…

分子网络 · 定量生物学 2014-12-02 Yann S. Dufour , Xiongfei Fu , Luis Hernandez-Nunez , Thierry Emonet

Feedback alignment algorithms are an alternative to backpropagation to train neural networks, whereby some of the partial derivatives that are required to compute the gradient are replaced by random terms. This essentially transforms the…

机器学习 · 计算机科学 2023-06-06 Dominique Chu , Florian Bacho

{\it E. coli} bacteria swim in straight runs interrupted by sudden reorientation events called tumbles. The resulting random walks give rise to density fluctuations that can be derived analytically in the limit of non interacting particles…

统计力学 · 物理学 2013-09-05 M. Paoluzzi , R. Di Leonardo , L. Angelani

Stability of running on rough terrain depends on the propagation of perturbations due to the ground. We consider stability within the sagittal plane and model the dynamics of running as a two-dimensional body with an alternating aerial and…

生物物理 · 物理学 2020-05-20 Nihav Dhawale , Shreyas Mandre , Madhusudhan Venkadesan

We study the long-time behaviour of a run and tumble model which is a kinetic-transport equation describing bacterial movement under the effect of a chemical stimulus. The experiments suggest that the non-uniform tumbling kernels are…

偏微分方程分析 · 数学 2024-04-30 Josephine Evans , Havva Yoldaş

The transport of a walker in rocking feedback-controlled ratchets are investigated. The walker consists of two coupled "feet" that allow the interchange of the order of the particles while the walker moves. In the underdamped case, the…

统计力学 · 物理学 2017-02-09 Tianfu Gao , Zhigang Zheng , Jincan Chen

Evolution has provided many organisms with sophisticated sensory systems that enable them to respond to signals in their environment. The response frequently involves alteration in the pattern of movement, such as the chemokinesis of the…

分子网络 · 定量生物学 2009-11-10 Reka Albert , Yu-wen Chiu , Hans G. Othmer

Highly nonlinear behavior of a system of discrete sites on a lattice is observed when a specific feedback loop is introduced into models employing coupled map lattices, quantum cellular automata, or the real-valued analogues of the latter.…

适应与自组织系统 · 物理学 2007-05-23 Siegfried Fussy , Gerhard Groessing , Herbert Schwabl

Standard approaches to controlling dynamical systems involve biologically implausible steps such as backpropagation of errors or intermediate model-based system representations. Recent advances in machine learning have shown that…

统计力学 · 物理学 2025-07-11 Carlos Floyd , Aaron R. Dinner , Suriyanarayanan Vaikuntanathan

We study the stochastic dynamics of a particle with two distinct motility states. Each one is characterized by two parameters: one represents the average speed and the other represents the persistence quantifying the tendency to maintain…

统计力学 · 物理学 2021-07-16 M. Reza Shaebani , Heiko Rieger

We study a random walk on $\mathbb{Z}$ which evolves in a dynamic environment determined by its own trajectory. Sites flip back and forth between two modes, $p$ and $q$. $R$ consecutive right jumps from a site in the $q$-mode are required…

概率论 · 数学 2015-03-05 Ross G. Pinsky , Nicholas F. Travers

Animals employ different strategies for relating sensory input to behavioral output to navigate sensory environments, but what strategy to use, when to switch and why remain unclear. In C. elegans, navigation is composed of 'steering' and…

神经元与认知 · 定量生物学 2025-08-04 Kevin S. Chen , Andrew M. Leifer , Jonathan W. Pillow

Kinetic-transport equations are, by now, standard models to describe the dynamics of populations of bacteria moving by run-and-tumble. Experimental observations show that bacteria increase their run duration when encountering an increasing…

偏微分方程分析 · 数学 2015-03-16 Benoît Perthame , Min Tang , Nicolas Vauchelet

Animals move smoothly and reliably in unpredictable environments. Models of sensorimotor control have assumed that sensory information from the environment leads to actions, which then act back on the environment, creating a single,…

神经元与认知 · 定量生物学 2023-01-11 Jing Shuang Li , Anish A. Sarma , Terrence J. Sejnowski , John C. Doyle

The quasi-coherent effects in two-dimensional incompressible turbulence are analyzed starting from the test particle trajectories. They can acquire coherent aspects when the stochastic potential has slow time variation and the motion is not…

等离子体物理 · 物理学 2017-04-05 M. Vlad , F. Spineanu

The pursuit-evasion game is studied for two adversarial active agents, modelled as a deterministic self-steering pursuer and a stochastic, cognitive evader. The pursuer chases the evader by reorienting its propulsion direction with limited…

生物物理 · 物理学 2026-05-29 Segun Goh , Dennis Haustein , Gerhard Gompper
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