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The use of FPGAs for efficient graph processing has attracted significant interest. Recent memory subsystem upgrades including the introduction of HBM in FPGAs promise to further alleviate memory bottlenecks. However, modern multi-channel…

硬件体系结构 · 计算机科学 2022-03-08 Xinyu Chen , Yao Chen , Feng Cheng , Hongshi Tan , Bingsheng He , Weng-Fai Wong

Metagenomic binning aims to cluster DNA fragments from mixed microbial samples into their respective genomes, a critical step for downstream analyses of microbial communities. Existing methods rely on deterministic representations, such as…

机器学习 · 计算机科学 2025-10-01 Abdulkadir Celikkanat , Andres R. Masegosa , Mads Albertsen , Thomas D. Nielsen

Antibiotic resistance presents a growing global health crisis, demanding new therapeutic strategies that target novel bacterial mechanisms. Recent advances in protein structure prediction and machine learning-driven molecule generation…

生物大分子 · 定量生物学 2025-05-22 Maximilian G. Schuh , Joshua Hesse , Stephan A. Sieber

By creating networks of biochemical pathways, communities of micro-organisms are able to modulate the properties of their environment and even the metabolic processes within their hosts. Next-generation high-throughput sequencing has led to…

应用统计 · 统计学 2023-03-28 Molly G. Hayes , Morgan G. I. Langille , Hong Gu

In the past few decades, the life sciences have experienced an unprecedented accumulation of data, ranging from genomic sequences and proteomic profiles to heavy-content imaging, clinical assays, and commercial biological products for…

数据库 · 计算机科学 2025-09-22 Rosalia Moreddu

Metagenome, a mixture of different genomes (as a rule, bacterial), represents a pattern, and the analysis of its composition is, currently, one of the challenging problems of bioinformatics. In the present study, the possibility of…

定量方法 · 定量生物学 2016-11-04 Valery Kirzhner , Zeev Volkovich , Renata Avros , Katerina Korenblat

Meta-analysis is a data aggregation method that establishes an overall and objective level of evidence based on the results of several studies. It is necessary to maintain a high level of homogeneity in the aggregation of data collected…

The microbiome constitutes a complex microbial ecology of interacting components that regulates important pathways in the host. Measurements of microbial abundances are key to learning the intricate network of interactions amongst microbes.…

统计方法学 · 统计学 2024-06-17 Veronica Vinciotti , Ernst Wit , Francisco Richter

The construction of large-scale, high-quality datasets is a fundamental prerequisite for developing robust and generalizable foundation models in motor imagery (MI)-based brain-computer interfaces (BCIs). However, EEG signals collected from…

计算工程、金融与科学 · 计算机科学 2025-06-16 Dingkun Liu , Zhu Chen , Dongrui Wu

To curate a high-quality dataset, identifying data variance between the internal and external sources is a fundamental and crucial step. However, methods to detect shift or variance in data have not been significantly researched. Challenges…

图像与视频处理 · 电气工程与系统科学 2021-12-30 Xiaoyuan Guo , Judy Wawira Gichoya , Hari Trivedi , Saptarshi Purkayastha , Imon Banerjee

Determining the trajectories of cells and their lineages or ancestries in live-cell experiments are fundamental to the understanding of how cells behave and divide. This paper proposes novel online algorithms for jointly tracking and…

信号处理 · 电气工程与系统科学 2021-10-29 Tran Thien Dat Nguyen , Ba-Ngu Vo , Ba-Tuong Vo , Du Yong Kim , Yu Suk Choi

This is a thought piece on data-intensive science requirements for databases and science centers. It argues that peta-scale datasets will be housed by science centers that provide substantial storage and processing for scientists who access…

数据库 · 计算机科学 2007-05-23 Jim Gray , David T. Liu , Maria Nieto-Santisteban , Alexander S. Szalay , David DeWitt , Gerd Heber

Advances in next-generation metagenome sequencing have the potential to revolutionize the point-of-care diagnosis of novel pathogen infections, which could help prevent potential widespread transmission of diseases. Given the high volume of…

Metagenomics has led to significant advances in many fields. Metagenomic analysis commonly involves the key tasks of determining the species present in a sample and their relative abundances. These tasks require searching large metagenomic…

Metainformation is a common companion to biomedical images. However, this potentially powerful additional source of signal from image acquisition has had limited use in deep learning methods, for semantic segmentation in particular. Here,…

图像与视频处理 · 电气工程与系统科学 2023-08-21 Iaroslav Plutenko , Mikhail Papkov , Kaupo Palo , Leopold Parts , Dmytro Fishman

Omnia presents a synthetic data driven pipeline to accelerate the training, validation, and deployment readiness of militarized humanoids. The approach converts first-person spatial observations captured from point-of-view recordings, smart…

机器人学 · 计算机科学 2025-12-17 Mohammed Ayman Habib , Aldo Petruzzelli

Grain Boundaries govern many properties of polycrystalline materials, including the vast majority of engineering materials. Evolutionary algorithm can be applied to predict the grain boundary structures in different systems. However, the…

材料科学 · 物理学 2017-10-04 Bingxi Li

Biodiversity research requires complete and detailed information to study ecosystem dynamics at different scales. Employing data-driven methods like Machine Learning is getting traction in ecology and more specific biodiversity, offering…

定量方法 · 定量生物学 2025-10-27 Stylianos Stasinos , Martino Mensio , Elena Lazovik , Athanasios Trantas

The MIMIC-IV dataset is a large, publicly available electronic health record (EHR) resource widely used for clinical machine learning research. It comprises multiple modalities, including structured data, clinical notes, waveforms, and…

Summary: Mapping ancient DNA to a reference genome is challenging as it involves numerous steps, is time-consuming and has to be repeated within a study to assess the quality of extracts and libraries; as a result, the mapping needs to be…