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There are many classical problems in P whose time complexities have not been improved over the past decades. Recent studies of "Hardness in P" have revealed that, for several of such problems, the current fastest algorithm is the best…

数据结构与算法 · 计算机科学 2017-10-24 Yoichi Iwata , Tomoaki Ogasawara , Naoto Ohsaka

Pedigrees, or family trees, are graphs of family relationships that are used to study inheritance. A fundamental problem in computational biology is to find, for a pedigree with $n$ individuals genotyped at every site, a set of…

数据结构与算法 · 计算机科学 2016-02-16 Bonnie Kirkpatrick

Genomes and genes diversify during evolution; however, it is unclear to what extent genes still retain the relationship among species. Model species for molecular phylogenetic studies include yeasts and viruses whose genomes were sequenced…

基因组学 · 定量生物学 2008-06-09 Yunfeng Shan , Xiu-Qing Li

Our goal is to visualize an additional data dimension of a tree with multifaceted data through superimposition on vertical strips, which we call columns. Specifically, we extend upward drawings of unordered rooted trees where vertices have…

计算几何 · 计算机科学 2023-09-06 Jonathan Klawitter , Johannes Zink

We present an algorithm for phylogenetic reconstruction using quartets that returns the correct topology for $n$ taxa in $O(n \log n)$ time with high probability, in a probabilistic model where a quartet is not consistent with the true…

种群与进化 · 定量生物学 2010-10-12 Daniel G. Brown , Jakub Truszkowski

The largest common embeddable subtree problem asks for the largest possible tree embeddable into two input trees and generalizes the classical maximum common subtree problem. Several variants of the problem in labeled and unlabeled rooted…

数据结构与算法 · 计算机科学 2018-05-03 Andre Droschinsky , Nils M. Kriege , Petra Mutzel

Phylogenetic networks are important for the study of evolution. The number of methods to find such networks is increasing, but most such methods can only reconstruct small networks. To find bigger networks, one can attempt to combine small…

离散数学 · 计算机科学 2019-12-10 Remie Janssen , Mark Jones , Yukihiro Murakami

Phylogenetic trees are leaf-labelled trees, where the leaves correspond to extant species (taxa), and the internal vertices represent ancestral species. The evolutionary history of a set of species can be explained by more than one…

数据结构与算法 · 计算机科学 2016-09-07 Asish Mukhopadhyay , Puspal Bhabak

Background: Tree reconciliation problems have long been studied in phylogenetics. A particular variant of the reconciliation problem for a gene tree T and a species tree S assumes that for each interior vertex x of T it is known whether x…

Phylogenetics is now fundamental in life sciences, providing insights into the earliest branches of life and the origins and spread of epidemics. However, finding suitable phylogenies from the vast space of possible trees remains…

种群与进化 · 定量生物学 2024-01-24 Matthew J Penn , Neil Scheidwasser , Joseph Penn , Christl A Donnelly , David A Duchêne , Samir Bhatt

A geophylogeny is a phylogenetic tree (or dendrogram) where each leaf (e.g. biological taxon) has an associated geographic location (site). To clearly visualize a geophylogeny, the tree is typically represented as a crossing-free drawing…

离散数学 · 计算机科学 2025-04-16 Jonathan Klawitter , Felix Klesen , Joris Y. Scholl , Thomas C. van Dijk , Alexander Zaft

The Persistent-Phylogeny Model is an extension of the widely studied Perfect-Phylogeny Model, encompassing a broader range of evolutionary phenomena. Biological and algorithmic questions concerning persistent phylogeny have been intensely…

种群与进化 · 定量生物学 2015-06-03 Dan Gusfield

We consider the multiple traveling salesman problem on a weighted tree. In this problem there are $m$ salesmen located at the root initially. Each of them will visit a subset of vertices and return to the root. The goal is to assign a tour…

数据结构与算法 · 计算机科学 2019-02-25 Lin Chen , Daniel Marx

The amount of completely sequenced chloroplast genomes increases rapidly every day, leading to the possibility to build large scale phylogenetic trees of plant species. Considering a subset of close plant species defined according to their…

We consider the NP-hard Tree Containment problem that has important applications in phylogenetics. The problem asks if a given leaf-labeled network contains a subdivision of a given leaf-labeled tree. We develop a fast algorithm for the…

计算复杂性 · 计算机科学 2017-02-22 Mathias Weller

Pedigree graphs, or family trees, are typically constructed by an expensive process of examining genealogical records to determine which pairs of individuals are parent and child. New methods to automate this process take as input genetic…

数据结构与算法 · 计算机科学 2011-10-19 Bonnie Kirkpatrick , Yakir Reshef , Hilary Finucane , Haitao Jiang , Binhai Zhu , Richard M. Karp

In this paper we investigate an extremal problem on binary phylogenetic trees. Given two such trees $T_1$ and $T_2$, both with leaf-set ${1,2,...,n}$, we are interested in the size of the largest subset $S \subseteq {1,2,...,n}$ of leaves…

组合数学 · 数学 2013-02-21 Daniel M. Martin , Bhalchandra D. Thatte

Phylogenetic trees are simple models of evolutionary processes. They describe conditionally independent divergent evolution of taxa from common ancestors. Phylogenetic trees commonly do not have enough flexibility to adequately model all…

种群与进化 · 定量生物学 2025-11-11 Jonathan D. Mitchell , Barbara R. Holland

Phylogenetic networks are a flexible model of evolution that can represent reticulate evolution and handle complex data. Tree-based networks, which are phylogenetic networks that have a spanning tree with the same root and leaf-set as the…

组合数学 · 数学 2023-05-25 Takatora Suzuki , Han Guo , Momoko Hayamizu

For a given graph $G$, a depth-first search (DFS) tree $T$ of $G$ is an $r$-rooted spanning tree such that every edge of $G$ is either an edge of $T$ or is between a \textit{descendant} and an \textit{ancestor} in $T$. A graph $G$ together…

数据结构与算法 · 计算机科学 2023-07-21 Emmanuel Sam , Benjamin Bergougnoux , Petr A. Golovach , Nello Blaser