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This paper aims to develop practical applications of the model for the highly technical measure-valued populations developed by the authors in \cite{FanEtal20}. We consider the problem of estimation of parameters in the general age and…

统计理论 · 数学 2025-06-30 Jie Yen Fan , Kais Hamza , Fima C. Klebaner , Ziwen Zhong

The interplay between space and evolution is an important issue in population dynamics, that is in particular crucial in the emergence of polymorphism and spatial patterns. Recently, biological studies suggest that invasion and evolution…

概率论 · 数学 2016-08-16 Nicolas Champagnat , Sylvie Méléard

In a stochastic volatility framework, we find a general pricing equation for the class of payoffs depending on the terminal value of a market asset and its final quadratic variation. This allows a pricing tool for European-style claims…

证券定价 · 定量金融 2012-06-12 Lorenzo Torricelli

Fractal behavior and long-range dependence have been observed in an astonishing number of physical systems. Either phenomenon has been modeled by self-similar random functions, thereby implying a linear relationship between fractal…

数据分析、统计与概率 · 物理学 2015-06-26 Tilmann Gneiting , Martin Schlather

The paper considers a particular family of set--valued stochastic processes modeling birth--and--growth processes. The proposed setting allows us to investigate the nucleation and the growth processes. A decomposition theorem is established…

应用统计 · 统计学 2011-09-29 Giacomo Aletti , Enea G. Bongiorno , Vincenzo Capasso

The study of stochastic variational principles involves the problem of constructing fixed-endpoint and adapted variations of semimartingales. We provide a detailed construction of variations of semimartingales that are not only fixed at…

数学物理 · 物理学 2025-09-11 Archishman Saha

The goal of the present paper is to explore the long-time behavior of the growth-fragmentation equation formulated in the case of equal mitosis and variability in growth rate, under fairly general assumptions on the coefficients. The first…

偏微分方程分析 · 数学 2025-03-10 Anaïs Rat , Magali Tournus

We consider the evolution of populations under the joint action of mutation and differential reproduction, or selection. The population is modelled as a finite-type Markov branching process in continuous time, and the associated…

种群与进化 · 定量生物学 2009-02-23 Ellen Baake , Hans-Otto Georgii

Motivated by tumor growth and spatial population genetics, we study the interplay between evolutionary and spatial dynamics at the surfaces of three-dimensional, spherical range expansions. We consider range expansion radii that grow with…

种群与进化 · 定量生物学 2015-06-02 Maxim O. Lavrentovich , David R. Nelson

A Profile Mixture Model is a model of protein evolution, describing sequence data in which sites are assumed to follow many related substitution processes on a single evolutionary tree. The processes depend in part on different amino acid…

种群与进化 · 定量生物学 2020-07-07 Samaneh Yourdkhani , Elizabeth S. Allman , John A. Rhodes

We analyze an interacting particle system with a Markov evolution of birth-and-death type. We have shown that a local competition mechanism (realized via a density dependent mortality) leads to a globally regular behavior of the population…

数学物理 · 物理学 2015-01-27 Dmitri Finkelshtein , Yuri Kondratiev , Oleksandr Kutoviy

The conditional survival function of a time-to-event outcome subject to censoring and truncation is a common target of estimation in survival analysis. This parameter may be of scientific interest and also often appears as a nuisance in…

统计方法学 · 统计学 2024-08-20 Charles J. Wolock , Peter B. Gilbert , Noah Simon , Marco Carone

This article presents a comprehensive study of the continuous McKendrick model, which serves as a foundational framework in population dynamics and epidemiology. The model is formulated through partial differential equations that describe…

种群与进化 · 定量生物学 2026-01-23 Dragos-Patru Covei

We study time continuous branching processes with exponentially distributed lifetimes, with two types of cells that proliferate according to binary fission. A range of possible system dynamics are considered, each of which is characterized…

概率论 · 数学 2022-04-27 Nam H Nguyen , Marek Kimmel

Random-matrix theory is applied to transition-rate matrices in the Pauli master equation. We study the distribution and correlations of eigenvalues, which govern the dynamics of complex stochastic systems. Both the cases of identical and of…

统计力学 · 物理学 2013-05-29 Carsten Timm

The recent interest in human dynamics has led researchers to investigate the stochastic processes that explain human behaviour in different contexts. Here we propose a generative model to capture the essential dynamics of survival analysis,…

物理与社会 · 物理学 2015-06-18 Trevor Fenner , Mark Levene , George Loizou

Modern biomedicine is challenged to predict the effects of genetic variation. Systematic functional assays of point mutants of proteins have provided valuable empirical information, but vast regions of sequence space remain unexplored.…

生物大分子 · 定量生物学 2017-01-18 Thomas A. Hopf , John B. Ingraham , Frank J. Poelwijk , Michael Springer , Chris Sander , Debora S. Marks

The stochastic growth-fragmentation model describes the temporal evolution of a structured cell population through a discrete-time and continuous-state Markov chain. The simulations of this stochastic process and its invariant measure are…

数值分析 · 数学 2025-05-20 Dawei Wu , Zhennan Zhou

We investigate the scaling properties of products of the exponential of birth--death processes with certain given marginal discrete distributions and covariance structures. The conditions on the mean, variance and covariance functions of…

统计理论 · 数学 2009-06-15 Vo V. Anh , Nikolai N. Leonenko , Narn-Rueih Shieh

We study the mathematical properties of a general model of cell division structured with several internal variables. We begin with a simpler and specific model with two variables, we solve the eigenvalue problem with strong or weak…

偏微分方程分析 · 数学 2008-10-08 Marie Doumic Jauffret