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Functional MRI (fMRI) is a powerful technique that has allowed us to characterize visual cortex responses to stimuli, yet such experiments are by nature constructed based on a priori hypotheses, limited to the set of images presented to the…

Computational modeling is becoming a widely used methodology in modern neuroscience. However, as the complexity of the phenomena under study increases, the analysis of the results emerging from the simulations concomitantly becomes more…

神经元与认知 · 定量生物学 2020-03-16 Sergio E. Galindo , Pablo Toharia , Oscar D. Robles , Eduardo Ros , Luis Pastor , Jesús A. Garrido

Sequential neuronal activity underlies a wide range of processes in the brain. Neuroscientific evidence for neuronal sequences has been reported in domains as diverse as perception, motor control, speech, spatial navigation and memory.…

适应与自组织系统 · 物理学 2020-04-03 Sascha Frölich , Dimitrije Marković , Stefan J. Kiebel

Single neurons in neural networks are often interpretable in that they represent individual, intuitively meaningful features. However, many neurons exhibit $\textit{mixed selectivity}$, i.e., they represent multiple unrelated features. A…

机器学习 · 统计学 2023-10-19 David Klindt , Sophia Sanborn , Francisco Acosta , Frédéric Poitevin , Nina Miolane

Integration between biology and information science benefits both fields. Many related models have been proposed, such as computational visual cognition models, computational motor control models, integrations of both and so on. In general,…

计算机视觉与模式识别 · 计算机科学 2016-03-28 Peijie Yin , Hong Qiao , Wei Wu , Lu Qi , YinLin Li , Shanlin Zhong , Bo Zhang

A popular theory of perceptual processing holds that the brain learns both a generative model of the world and a paired recognition model using variational Bayesian inference. Most hypotheses of how the brain might learn these models assume…

神经元与认知 · 定量生物学 2021-06-01 Ari S. Benjamin , Konrad P. Kording

For three decades statistical mechanics has been providing a framework to analyse neural networks. However, the theoretically tractable models, e.g., perceptrons, random features models and kernel machines, or multi-index models and…

机器学习 · 统计学 2025-06-02 Jean Barbier , Francesco Camilli , Minh-Toan Nguyen , Mauro Pastore , Rudy Skerk

Biological data sets are often high-dimensional, noisy, and governed by complex interactions among sparse signals. This poses major challenges for interpretability and reliable feature selection. Tasks such as identifying motif interactions…

统计方法学 · 统计学 2025-11-20 Marta S. Lemanczyk , Lucas Kock , Johanna Schlimme , Nadja Klein , Bernhard Y. Renard

Various brain functions that are necessary to maintain life activities materialize through the interaction of countless neurons. Therefore, it is important to analyze functional neuronal network. To elucidate the mechanism of brain…

神经元与认知 · 定量生物学 2023-06-29 Shun Kimura , Koujin Takeda

Selection bias arises when the probability that an observation enters a dataset depends on variables related to the quantities of interest, leading to systematic distortions in estimation and uncertainty quantification. For example, in…

We present a new approach to the electromagnetic inverse problem that explicitly addresses the ambiguity associated with its ill-posed character. Rather than calculating a single ``best'' solution according to some criterion, our approach…

神经元与认知 · 定量生物学 2007-05-23 David M. Schmidt , John S. George , C. C. Wood

Recently, interest has grown in exploring the hypothesis that neural activity conveys information through precise spiking motifs. To investigate this phenomenon, various algorithms have been proposed to detect such motifs in Single Unit…

神经元与认知 · 定量生物学 2023-09-27 Laurent U Perrinet

Identifying stimulus-driven neural activity patterns is critical for studying the neural basis of cognition. This can be particularly challenging in intracranial datasets, where electrode locations typically vary across patients. This…

神经元与认知 · 定量生物学 2022-02-07 Jeremy R. Manning

Feedforward neural networks (FNNs) can be viewed as non-linear regression models, where covariates enter the model through a combination of weighted summations and non-linear functions. Although these models have some similarities to the…

统计方法学 · 统计学 2024-05-02 Andrew McInerney , Kevin Burke

Tactile afferents such as (RA), and Pacinian (PC) afferents that respond to external stimuli enable complicated actions such as grasping, stroking and identifying an object. To understand the tactile sensation induced by these actions…

机器人学 · 计算机科学 2022-08-02 Hiroki Ishizuka , Shoki Kitaguchi , Masashi Nakatani , Hidenori Yoshimura , Fusao Shimokawa

Over the last few decades, psychologists have developed sophisticated formal models of human categorization using simple artificial stimuli. In this paper, we use modern machine learning methods to extend this work into the realm of…

计算机视觉与模式识别 · 计算机科学 2017-11-15 Ruairidh M. Battleday , Joshua C. Peterson , Thomas L. Griffiths

Neural network models comprising elements which have exclusively excitatory or inhibitory synapses are capable of a wide range of dynamic behavior, including chaos. In this paper, a simple excitatory-inhibitory neural pair, which forms the…

无序系统与神经网络 · 物理学 2009-10-31 Sitabhra Sinha , Jayanta Basak

Longitudinal item response data are common in social science, educational science, and psychology, among other disciplines. Studying the time-varying relationships between items is crucial for educational assessment or designing marketing…

统计方法学 · 统计学 2021-10-26 Jaewoo Park , Yeseul Jeon , Minsuk Shin , Minjeong Jeon , Ick Hoon Jin

To gain insight into the neural events responsible for visual perception of static and dynamic optical patterns, we study how neural activation spreads in arrays of inhibition-stabilized neural networks with nearest-neighbor coupling. The…

神经元与认知 · 定量生物学 2016-09-02 Sergey Savel'ev , Sergei Gepshtein

Understanding the relation between cortical neuronal network structure and neuronal activity is a fundamental unresolved question in neuroscience, with implications to our understanding of the mechanism by which neuronal networks evolve…