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Subtle alterations in brain network topology often evade detection by traditional statistical methods. To address this limitation, we introduce a Bayesian inference framework for topological comparison of brain networks that…

统计方法学 · 统计学 2025-11-06 Xukun Zhu , Michael W Lutz , Tananun Songdechakraiwut

Structural and functional neuroimaging modalities provide complementary windows into brain organization: structural imaging characterizes neural tissue anatomy and microstructure, while functional imaging captures dynamic patterns of neural…

统计方法学 · 统计学 2026-03-24 Sakul Mahat , Sharmistha Guha , Jessica Bernard

Patterns of brain activity are associated with different brain processes and can be used to identify different brain states and make behavioral predictions. However, the relevant features are not readily apparent and accessible. To mine…

Brain decoding involves the determination of a subject's cognitive state or an associated stimulus from functional neuroimaging data measuring brain activity. In this setting the cognitive state is typically characterized by an element of a…

机器学习 · 统计学 2015-04-14 Nicole Croteau , Farouk S. Nathoo , Jiguo Cao , Ryan Budney

Bayesian models of behavior have provided computational level explanations in a range of psychophysical tasks. One fundamental experimental paradigm is the production or reproduction task, in which subjects are instructed to generate an…

机器学习 · 计算机科学 2022-01-03 Nils Neupärtl , Constantin A. Rothkopf

Mechanistic models of single-neuron dynamics have been extensively studied in computational neuroscience. However, identifying which models can quantitatively reproduce empirically measured data has been challenging. We propose to overcome…

We propose a method that would allow for a rigorous statistical analysis of neural responses to natural stimuli, which are non-Gaussian and exhibit strong correlations. We have in mind a model in which neurons are selective for a small…

生物物理 · 物理学 2007-05-23 Tatyana Sharpee , Nicole C. Rust , William Bialek

Brains learn to represent information from a large set of stimuli, typically by weak supervision. Unsupervised learning is therefore a natural approach for exploring the design of biological neural networks and their computations.…

神经元与认知 · 定量生物学 2025-10-17 Roy Urbach , Elad Schneidman

Advances in large-scale neural recordings have expanded our ability to describe the activity of distributed brain circuits. However, understanding how neural population dynamics differ across regions and behavioral contexts remains…

Deducing the structure of neural circuits is one of the central problems of modern neuroscience. Recently-introduced calcium fluorescent imaging methods permit experimentalists to observe network activity in large populations of neurons,…

应用统计 · 统计学 2011-07-22 Yuriy Mishchencko , Joshua T. Vogelstein , Liam Paninski

Promising results have driven a recent surge of interest in continuous optimization methods for Bayesian network structure learning from observational data. However, there are theoretical limitations on the identifiability of underlying…

This thesis delves into the world of non-invasive electrophysiological brain signals like electroencephalography (EEG) and magnetoencephalography (MEG), focusing on modelling and decoding such data. The research aims to investigate what…

信号处理 · 电气工程与系统科学 2025-10-30 Richard Csaky

Quantitative modeling of human brain activity based on language representations has been actively studied in systems neuroscience. However, previous studies examined word-level representation, and little is known about whether we could…

计算机视觉与模式识别 · 计算机科学 2018-02-08 Eri Matsuo , Ichiro Kobayashi , Shinji Nishimoto , Satoshi Nishida , Hideki Asoh

Brain function is organized in coordinated modes of spatio-temporal activity (functional networks) exhibiting an intrinsic baseline structure with variations under different experimental conditions. Existing approaches for uncovering such…

统计方法学 · 统计学 2019-02-13 Joshua Lukemire , Suprateek Kundu , Giuseppe Pagnoni , Ying Guo

How does the brain know what is out there and what is not? Living organisms cannot rely solely on sensory signals for perception because they are noisy and ambiguous. To transform sensory signals into stable percepts, the brain uses its…

神经元与认知 · 定量生物学 2025-11-27 Alejandro Tabas , Heike Sönnichsen , Sandeep Kaur , Marco Meixner , Katharina von Kriegstein

Brain decoding is a field of computational neuroscience that uses measurable brain activity to infer mental states or internal representations of perceptual inputs. Therefore, we propose a novel approach to brain decoding that also relies…

计算机视觉与模式识别 · 计算机科学 2023-03-23 Matteo Ferrante , Tommaso Boccato , Nicola Toschi

Detecting shared neural activity from functional magnetic resonance imaging (fMRI) across individuals exposed to the same stimulus can reveal synchronous brain responses, functional roles of regions, and potential clinical biomarkers.…

应用统计 · 统计学 2026-04-24 Spencer Wadsworth , Nabin Koirala , Nicole Landi , Ofer Harel

Neurons can display highly variable dynamics. While such variability presumably supports the wide range of behaviors generated by the organism, their gene expressions are relatively stable in the adult brain. This suggests that neuronal…

神经元与认知 · 定量生物学 2023-11-07 Lu Mi , Trung Le , Tianxing He , Eli Shlizerman , Uygar Sümbül

Humans leverage compositionality to efficiently learn new concepts, understanding how familiar parts can combine together to form novel objects. In contrast, popular computer vision models struggle to make the same types of inferences,…

计算机视觉与模式识别 · 计算机科学 2023-06-01 Yanli Zhou , Reuben Feinman , Brenden M. Lake

Decoding visual stimuli from neural responses recorded by functional Magnetic Resonance Imaging (fMRI) presents an intriguing intersection between cognitive neuroscience and machine learning, promising advancements in understanding human…

计算机视觉与模式识别 · 计算机科学 2023-12-29 Jingyuan Sun , Mingxiao Li , Zijiao Chen , Yunhao Zhang , Shaonan Wang , Marie-Francine Moens