相关论文: Developing a new biophysical tool to combine magne…

Control over the quantum states of individual molecules is crucial in the quest to harness their rich internal structure and dipolar interactions for applications in quantum science. In this paper, we develop a toolbox of techniques for the…

Optical tweezers, which are powerful tools for trapping and manipulating particles, have been widely used in many areas. However, their potential wells are typically symmetrical, which limit their capability of optical trapping and…

Recent technological advances in cutting-edge ultrasensitive fluorescence microscopy have allowed single-molecule imaging experiments in living cells across all three domains of life to become commonplace. Single-molecule live-cell data is…

This work presents the first optical trapping experimental demonstration of micro-particles with Frozen Waves. Frozen Waves are an efficient method to model longitudinally the intensity of non-diffracting beams obtained by superposing…

It is common to introduce optical tweezers using either geometric optics for large particles or the Rayleigh approximation for very small particles. These approaches are successful at conveying the key ideas behind optical tweezers in their…

Optical tweezers has emerged as a powerful tool in manipulating microscopic particles and in measuring weak forces of the order of a pico-Newton. As a result, it has found wide applications ranging from material science to biology.…

Bacterial biofilms underlie many persistent infections, posing major hurdles in antibiotic treatment. Here, we design and demonstrate tug-of-war optical tweezers that can facilitate assessment of cell-cell adhesion - a key contributing…

Optical tweezers are an invaluable tool for non-contact trapping and micro-manipulation, but their ability to facilitate high-throughput volumetric microrheology of biological samples for mechanobiology research is limited by the precise…

Single-molecule microscopy has become an indispensable tool for biochemical analysis. The capability of characterizing distinct properties of individual molecules without averaging has provided us with a different perspective for the…

Optical tweezers have been widely used for optical manipulation of various particles. At present, there are different type of optical tweezers. Among them, holographic optical tweezers have attracted growing attention as a powerful tools…

We present a novel approach to precisely synthesize arbitrary polarization states of light with a high modulation bandwidth. Our approach consists of superimposing two laser light fields with the same wavelength, but with opposite circular…

Mode-locked lasers, which produce ultrashort pulses in the picosecond and femtosecond range, have enabled some of the most precise measurements. However, despite significant recent progress, resolving the temporal behavior of their short…

Recently, computational sampling methods have been implemented to spatially characterize terahertz (THz) fields. Previous methods usually rely on either specialized THz devices such as THz spatial light modulators, or complicated systems…

We demonstrate single-shot imaging and narrow-line cooling of individual alkaline earth atoms in optical tweezers; specifically, strontium-88 atoms trapped in $515.2~\text{nm}$ light. We achieve high-fidelity single-atom-resolved imaging by…

DNA-interacting proteins have roles multiple processes, many operating as molecular machines which undergo dynamic metastable transitions to bring about their biological function. To fully understand this molecular heterogeneity, DNA and…

Advances in laser and optoelectronic technologies brought the general concept of optomechanical manipulation to the level of standard biophysical tools, paving ways towards controlled experiments and measurements of tiny mechanical forces.…

Fluorescence lifetime imaging microscopy (FLIM) is an important technique to understand the chemical micro-environment in cells and tissues since it provides additional contrast compared to conventional fluorescence imaging. When two…

This study formally adapts the time-domain linear sampling method (TLSM) for ultrasonic imaging of stationary and evolving fractures in safety-critical components. The TLSM indicator is then applied to the laboratory test data of [22, 18]…

Ultrasound Localization Microscopy (ULM) enables imaging of vascular structures in the micrometer range by accumulating contrast agent particle locations over time. Precise and efficient target localization accuracy remains an active…

We report a new coherent imaging technique, termed ptychographic structured modulation (PSM), for quantitative super-resolution microscopy. In this technique, we place a thin diffuser (i.e., a scattering lens) in between the sample and the…