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We develop an general formalism of single enzyme kinetics in two dimension where substrates diffuse stochastically on a square lattice in presence of disorder. The dynamics of the model could be decoupled effectively to two stochastic…

化学物理 · 物理学 2009-01-20 Mahashweta Basu , P. K. Mohanty

The Quasi Steady-State (QSS) model of long-term dynamics relies on the idea of time-scale decomposition. Assuming that the fast variables are infinitely fast and are stable in the long-term, the QSS model replaces the differential equations…

系统与控制 · 计算机科学 2013-10-02 Xiaozhe Wang , Hsiao-Dong Chiang

In this paper, we develop a method for obtaining the approximate solution for the evolution of single-step transformations under non-isothermal conditions. We have applied it to many reaction models and obtained very simple analytical…

材料科学 · 物理学 2008-11-11 Jordi Farjas , Pere Roura

The first experimental demonstration of an adaptive quantum state estimation (AQSE) is reported. The strong consistency and asymptotic efficiency of AQSE have been mathematically proven [ A. Fujiwara J. Phys. A 39 12489 (2006)]. In this…

Mathematical analysis of mass action models of large complex chemical systems is typically only possible if the models are reduced. The most common reduction technique is based on quasi-steady state assumptions. To increase the accuracy of…

动力系统 · 数学 2014-11-04 Tomáš Vejchodský , Radek Erban , Philip K. Maini

We present a model of an ATP-fueled molecular machine which push a polymer through a pore channel. The machine acts between two levels (working-waiting), and the working one remains active for a fixed time giving a constant force. The…

软凝聚态物质 · 物理学 2012-02-24 Alessandro Fiasconaro , Juan José Mazo , Fernando Falo

We consider the application of Kramers theory to the microscopic calculation of rates of conformational transitions of macromolecules. The main difficulty in such an approach is to locate the transition state in a huge configuration space.…

生物大分子 · 定量生物学 2008-09-02 Marcello Sega , Pietro Faccioli , Francesco Pederiva , Henri Orland

Quasicentroid molecular dynamics (QCMD) is a path-integral method for approximating nuclear quantum effects in dynamics simulations, which has given promising results for gas- and condensed-phase water. Here, by simulating the infrared…

Finding optimal reaction coordinates and predicting accurate kinetic rates for activated processes are two of the foremost challenges of molecular simulations. We introduce an algorithm that tackles the two problems at once: starting from a…

统计力学 · 物理学 2023-10-30 Line Mouaffac , Karen Palacio-Rodriguez , Fabio Pietrucci

Previous studies have primarily focused on the nonequilibrium thermodynamics of chemical reaction networks (CRNs) occurring in closed systems. In contrast, CRNs in open systems exhibit much richer nonequilibrium phenomena due to sustained…

化学物理 · 物理学 2025-04-14 Xinyu Zhang , Haiyang Jia , Liangrong Peng , Liu Hong

Results are presented for the quench dynamics of a clean and interacting electron system, where the quench involves varying the strength of the attractive interaction along arbitrary quench trajectories. The initial state before the quench…

超导电性 · 物理学 2019-09-04 Yonah Lemonik , Aditi Mitra

The concept of entropy and the correct application of the Second Law of thermodynamics are essential in order to understand the reason why quantum error correction is thermodynamically possible and no violation of the Second Law occurs…

量子物理 · 物理学 2015-06-16 Carlo Cafaro , Peter van Loock

The chemical birth-death process, whose chemical master equation (CME) is exactly solvable, is a paradigmatic toy problem often used to get intuition for how stochasticity affects chemical kinetics. In a certain limit, it can be…

定量方法 · 定量生物学 2019-10-22 John J. Vastola

The statistical problem of the distribution of $s$ quanta of equal energy $\epsilon_0$ and total energy $E$ among $N$ distinguishable particles is resolved using the conventional theory based on Boltzmann's principle of equal probabilities…

量子物理 · 物理学 2021-11-18 Michalis Psimopoulos , Emilie Dafflon

Particle-based simulations are an essential tool for the study of biochemical systems for scales between molecular/Brownian dynamics and the reaction-diffusion master equation. These simulations utilise proximity-based reaction conditions…

生物物理 · 物理学 2025-08-18 Taylor Kearney , Mark B. Flegg

Applying probabilistic techniques we study regularity properties of quantum master equations (QMEs) in the Lindblad form with unbounded coefficients; a density operator is regular if, roughly speaking, it describes a quantum state with…

概率论 · 数学 2013-07-09 Carlos M. Mora

The quantum relative entropy is a fundamental quantity in quantum information science, characterizing the distinguishability between two quantum states. However, this quantity is not additive in general for correlated quantum states,…

量子物理 · 物理学 2025-06-05 Kun Fang , Hamza Fawzi , Omar Fawzi

Models invoking the chemical master equation are used in many areas of science, and, hence, their simulation is of interest to many researchers. The complexity of the problems at hand often requires considerable computational power, so a…

生物物理 · 物理学 2016-03-02 Fabian Spill , Philip K. Maini , Helen Byrne

Antisymmetrized molecular dynamics (AMD) with quantum branching processes is reformulated so that it can be applicable to the collisions of heavy nuclei such as Au + Au multifragmentation reactions. The quantum branching process due to the…

核理论 · 物理学 2009-10-31 Akira Ono

We study networks of biochemical reactions modelled by continuous-time Markov processes. Such networks typically contain many molecular species and reactions and are hard to study analytically as well as by simulation. Particularly, we are…

分子网络 · 定量生物学 2018-05-22 Daniele Cappelletti , Carsten Wiuf