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The periodic transference of nucleotide strings in bacterial and archaeal complete genomes is investigated by using the metric representation and the recurrence plot method. The generated periodic correlation structures exhibit four kinds…

基因组学 · 定量生物学 2013-03-01 Zuo-Bing Wu

In the absence of synaptic coupling, two or more neural oscillators may become synchronized by virtue of the statistical correlations in their noisy input streams. Recent work has shown that the degree of correlation transfer from input…

动力系统 · 数学 2015-03-17 Aushra Abouzeid , Bard Ermentrout

Over the brief time intervals available for processing retinal output, roughly 50 to 300 msec, the number of extra spikes generated by individual ganglion cells can be quite variable. Here, computer-generated spike trains were used to…

神经元与认知 · 定量生物学 2007-09-14 Garrett T. Kenyon

This paper introduces a new family of reconstruction codes which is motivated by applications in DNA data storage and sequencing. In such applications, DNA strands are sequenced by reading some subset of their substrings. While previous…

信息论 · 计算机科学 2022-05-10 Yonatan Yehezkeally , Daniella Bar-Lev , Sagi Marcovich , Eitan Yaakobi

During evolution of microorganisms genomes underwork have different changes in their lengths, gene orders, and gene contents. Investigating these structural rearrangements helps to understand how genomes have been modified over time. Some…

基因组学 · 定量生物学 2017-06-27 Huda Al-Nayyef , Christophe Guyeux , Marie Petitjean , Didier Hocquet , Jacques M. Bahi

Macroscopic oscillations of different brain regions show multiple phase relationships that are persistent across time and have been implicated routing information. Various cellular level mechanisms influence the network dynamics and…

神经元与认知 · 定量生物学 2019-06-19 Gregory Dumont , Boris Gutkin

Genomes evolve as modules. In prokaryotes (and some eukaryotes), genetic material can be transferred between species and integrated into the genome via homologous or illegitimate recombination. There is little reason to imagine that the…

基因组学 · 定量生物学 2008-01-29 Cheong Xin Chan , Robert G. Beiko , Aaron E. Darling , Mark A. Ragan

This paper studies the problem of encoding messages into sequences which can be uniquely recovered from some noisy observations about their substrings. The observed reads comprise consecutive substrings with some given minimum overlap. This…

信息论 · 计算机科学 2023-12-11 Hengjia Wei , Moshe Schwartz , Gennian Ge

Neuronal dynamics are fundamentally constrained by the underlying structural network architecture, yet much of the details of this synaptic connectivity are still unknown even in neuronal cultures in vitro. Here we extend a previous…

神经元与认知 · 定量生物学 2017-02-08 Javier G. Orlandi , Olav Stetter , Jordi Soriano , Theo Geisel , Demian Battaglia

The analysis of correlations of amino acid occurrences in globular proteins has led to the development of statistical tools that can identify native contacts -- portions of the chains that come to close distance in folded structural…

生物大分子 · 定量生物学 2014-07-28 Rocío Espada , R. Gonzalo Parra , Thierry Mora , Aleksandra M. Walczak , Diego Ferreiro

Using transfer matrices up to next-nearest-neighbour (NNN) interactions, we examine the structural correlations of quasi-one-dimensional systems of hard disks confined by two parallel lines and hard spheres confined in cylinders.…

软凝聚态物质 · 物理学 2022-05-03 Yi Hu , Lin Fu , Patrick Charbonneau

K-core percolation is a fundamental dynamical process in complex networks with applications that span numerous real-world systems. Earlier studies focus primarily on random networks without spatial constraints and reveal intriguing…

物理与社会 · 物理学 2024-07-12 Leyang Xue , Shengling Gao , Lazaros K. Gallos , Orr Levy , Bnaya Gross , Zengru Di , Shlomo Havlin

Motivation: DNA data is transcribed into single-stranded RNA, which folds into specific molecular structures. In this paper we pose the question to what extent sequence- and structure-information correlate. We view this correlation as…

组合数学 · 数学 2016-08-23 Christopher Barrett , Fenix W. Huang , Christian M. Reidys

Genetic sequences are known to possess non-trivial composition together with symmetries in the frequencies of their components. Recently, it has been shown that symmetry and structure are hierarchically intertwined in DNA, suggesting a…

基因组学 · 定量生物学 2020-09-28 Giampaolo Cristadoro , Mirko Degli Esposti , Eduardo G. Altmann

De novo genome assembly, i.e., rebuilding the sequence of an unknown genome from redundant and erroneous short sequences, is a key but computationally intensive step in many genomics pipelines. The exponential growth of genomic data is…

分布式、并行与集群计算 · 计算机科学 2022-07-12 Giulia Guidi , Gabriel Raulet , Daniel Rokhsar , Leonid Oliker , Katherine Yelick , Aydin Buluc

Nuclear pore complexes (NPCs) mediate the exchange of materials between the nucleoplasm and cytoplasm, playing a key role in the separation of nucleic acids and proteins into their required compartments. The static structure of the NPC is…

生物大分子 · 定量生物学 2023-04-07 David Cowburn , Michael Rout

We study a minimal model for genome evolution whose elementary processes are single site mutation, duplication and deletion of sequence regions and insertion of random segments. These processes are found to generate long-range correlations…

基因组学 · 定量生物学 2007-05-23 Philipp W. Messer , Peter F. Arndt , Michael Lässig

This paper introduces a new family of reconstruction codes which is motivated by applications in DNA data storage and sequencing. In such applications, DNA strands are sequenced by reading some subset of their substrings. While previous…

信息论 · 计算机科学 2023-04-21 Yonatan Yehezkeally , Daniella Bar-Lev , Sagi Marcovich , Eitan Yaakobi

Network remodeling, or adaptation, in the presence of periodically driven forcings has hereto remained largely unexplored, despite the fact that a broad class of biological transport networks, e.g. animal vasculature, depends on periodic…

适应与自组织系统 · 物理学 2026-01-01 Purba Chatterjee , Eleni Katifori

Biologists have long sought a way to explain how statistical properties of genetic sequences emerged and are maintained through evolution. On the one hand, non-random structures at different scales indicate a complex genome organisation. On…

定量方法 · 定量生物学 2018-11-01 Giampaolo Cristadoro , Mirko Degli Esposti , Eduardo G. Altmann
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