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There has been a substantial amount of research on the relationship between hippocampal neurogenesis and behaviour over the past fifteen years, but the causal role that new neurons have on cognitive and affective behavioural tasks is still…

神经元与认知 · 定量生物学 2014-11-11 Stanley E. Lazic

The aim of this study was to estimate the number of new cells and neurons added to the dentate gyrus across the lifespan, and to compare the rate of age-associated decline in neurogenesis across species. Data from mice (Mus musculus), rats…

神经元与认知 · 定量生物学 2011-05-05 Stanley E. Lazic

Individual neurons often produce highly variable responses over nominally identical trials, reflecting a mixture of intrinsic "noise" and systematic changes in the animal's cognitive and behavioral state. Disentangling these sources of…

神经元与认知 · 定量生物学 2021-11-08 Alex H. Williams , Scott W. Linderman

Adult neurogenesis has long been documented in the vertebrate brain, and recently even in humans. Although it has been conjectured for many years that its functional role is related to the renewing of memories, no clear mechanism as to how…

无序系统与神经网络 · 物理学 2007-05-23 Guillermo A. Cecchi , Leopoldo T. Petreanu , Arturo Alvarez-Buylla , Marcelo O. Magnasco

Recent advancements in measurement techniques have resulted in an increasing amount of data on neural activities recorded in parallel, revealing largely heterogeneous correlation patterns across neurons. Yet, the mechanistic origin of this…

无序系统与神经网络 · 物理学 2024-04-26 Moritz Layer , Moritz Helias , David Dahmen

This review examines the evidence in the literature for physiological co-modulation during human-animal interaction. The aim of this work is to identify studies that assessed co-modulation via simultaneous measurement of physiological…

神经元与认知 · 定量生物学 2025-10-14 G. Bargigli , L. Frassineti , A. Lanata' , P. Baragli , C. Scopa , A. Vignoli

Plasticity is one of the most important properties of the nervous system, which enables animals to adjust their behavior to the ever-changing external environment. Changes in synaptic efficacy between neurons constitute one of the major…

神经元与认知 · 定量生物学 2018-01-23 Taishi Iwasaki , Hideitsu Hino , Masami Tatsuno , Shotaro Akaho , Noboru Murata

Experimental results in recent years have shown that adult neurogenesis is a significant phenomenon in the mammalian brain. Little is known, however, about the functional role played by the generation and destruction of neurons in the…

神经元与认知 · 定量生物学 2009-11-10 Guillermo A. Cecchi , Marcelo O. Magnasco

Many systems neuroscientists want to understand neurons in terms of mediation; we want to understand how neurons are involved in the causal chain from stimulus to behavior. Unfortunately, most tools are inappropriate for that while our…

神经元与认知 · 定量生物学 2020-09-04 Ilenna Simone Jones , Konrad Paul Kording

Interactive intelligent agents are being integrated across society. Despite achieving human-like capabilities, humans' responses to these agents remain poorly understood, with research fragmented across disciplines. We conducted a first…

人机交互 · 计算机科学 2026-05-07 Jianan Zhou , Fleur Corbett , Joori Byun , Talya Porat , Nejra van Zalk

Perceptions and actions, thoughts and memories result from coordinated activity in hundreds or even thousands of neurons in the brain. It is an old dream of the physics community to provide a statistical mechanics description for these and…

无序系统与神经网络 · 物理学 2024-09-04 Leenoy Meshulam , William Bialek

How accurately can behavioral scientists predict behavior? To answer this question, we analyzed data from five studies in which 640 professional behavioral scientists predicted the results of one or more behavioral science experiments. We…

综合经济学 · 经济学 2022-08-03 Dillon Bowen

For the last decade, convolutional neural networks (CNNs) have vastly superseded their predecessors in nearly all vision tasks in artificial intelligence, including object recognition. However, despite abundant advancements, they continue…

计算机视觉与模式识别 · 计算机科学 2023-02-09 Brandon RichardWebster , Justin Dulay , Anthony DiFalco , Elisabetta Caldesi , Walter J. Scheirer

We consider signal transaction in a simple neuronal model featuring intrinsic noise. The presence of noise limits the precision of neural responses and impacts the quality of neural signal transduction. We assess the signal transduction…

生物物理 · 物理学 2015-03-17 Michael J. Barber , Manfred L. Ristig

Rapid anthropogenic environmental changes, including those due to habitat contamination, degradation, and climate change, have far-reaching effects on biological systems that may outpace animals' adaptive responses (Radchuk et al., 2019).…

神经元与认知 · 定量生物学 2022-10-17 Angie Michaiel , Amy Bernard

In many systems we can describe emergent macroscopic behaviors, quantitatively, using models that are much simpler than the underlying microscopic interactions; we understand the success of this simplification through the renormalization…

生物物理 · 物理学 2019-01-01 Leenoy Meshulam , Jeffrey L. Gauthier , Carlos D. Brody , David W. Tank , William Bialek

Humans and animals exhibit a range of interesting behaviors in dynamic environments, and it is unclear how our brains actively reformat this dense sensory information to enable these behaviors. Experimental neuroscience is undergoing a…

神经元与认知 · 定量生物学 2023-11-07 Aran Nayebi

Behaviour change lies at the heart of many observable collective phenomena such as the transmission and control of infectious diseases, adoption of public health policies, and migration of animals to new habitats. Representing the process…

定量方法 · 定量生物学 2025-09-03 Roben Delos Reyes , Hugo Lyons Keenan , Cameron Zachreson

A primary difficulty with unsupervised discovery of structure in large data sets is a lack of quantitative evaluation criteria. In this work, we propose and investigate several metrics for evaluating and comparing generative models of…

机器学习 · 计算机科学 2020-07-27 Daniel Jiwoong Im , Iljung Kwak , Kristin Branson

In many psychophysical detection and discrimination tasks human performance is thought to be limited by internal or inner noise when neuronal activity is converted into an overt behavioural response. It is unclear, however, to what extent…

神经元与认知 · 定量生物学 2024-12-03 Jesus Malo , Jose Juan Esteve-Taboada , Guillermo Aguilar , Marianne Maertens , Felix A. Wichmann
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