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Accurate predictions of pollutant concentrations at new locations are often of interest in air pollution studies on fine particulate matters (PM$_{2.5}$), in which data is usually not measured at all study locations. PM$_{2.5}$ is also a…

应用统计 · 统计学 2020-05-19 Phuong T. Vu , Timothy V. Larson , Adam A. Szpiro

We study semiparametric factor models in high-dimensional panels where the factor loadings consist of a nonparametric component explained by observed covariates and an idiosyncratic component capturing unobserved heterogeneity. A key…

统计方法学 · 统计学 2025-12-09 Sijie Zheng

Matrix factor model has been growing popular in scientific fields such as econometrics, which serves as a two-way dimension reduction tool for matrix sequences. In this article, we for the first time propose the matrix elliptical factor…

统计方法学 · 统计学 2022-03-29 ZeYu Li , Yong He , Xinbing Kong , Xinsheng Zhang

Many studies of neural activity in behaving animals aim to discover interpretable low-dimensional structure in large-scale neural population recordings. One approach to this problem is demixed principal component analysis (dPCA), a…

神经元与认知 · 定量生物学 2019-12-11 Kenneth W. Latimer

Principal Component Analysis is a key technique for reducing the complexity of high-dimensional data while preserving its fundamental data structure, ensuring models remain stable and interpretable. This is achieved by transforming the…

统计方法学 · 统计学 2025-03-25 Nuwan Weeraratne , Lyn Hunt , Jason Kurz

Modal analysis techniques are used to identify patterns and develop reduced-order models in a variety of fluid applications. However, experimentally acquired flow fields may be corrupted with incorrect and missing entries, which may degrade…

This paper proposes a probabilistic neural network developed on the basis of time-series discriminant component analysis (TSDCA) that can be used to classify high-dimensional time-series patterns. TSDCA involves the compression of…

机器学习 · 计算机科学 2019-11-15 Hideaki Hayashi , Taro Shibanoki , Keisuke Shima , Yuichi Kurita , Toshio Tsuji

In areas of application, including actuarial science and demography, it is increasingly common to consider a time series of curves; an example of this is age-specific mortality rates observed over a period of years. Given that age can be…

应用统计 · 统计学 2020-09-29 Han Lin Shang

Over the years, Principal Component Analysis (PCA) has served as the baseline approach for dimensionality reduction in gene expression data analysis. It primary objective is to identify a subset of disease-causing genes from a vast pool of…

代数拓扑 · 数学 2023-06-13 Sean Cottrell , Rui Wang , Guowei Wei

High-dimensional multivariate longitudinal data, which arise when many outcome variables are measured repeatedly over time, are becoming increasingly common in social, behavioral and health sciences. We propose a latent variable model for…

统计方法学 · 统计学 2025-12-09 Sze Ming Lee , Yunxiao Chen , Tony Sit

We propose generalized conditional functional principal components analysis (GC-FPCA) for the joint modeling of the fixed and random effects of non-Gaussian functional outcomes. The method scales up to very large functional data sets by…

统计方法学 · 统计学 2024-11-18 Yu Lu , Xinkai Zhou , Erjia Cui , Dustin Rogers , Ciprian M. Crainiceanu , Julia Wrobel , Andrew Leroux

Modern population genetics studies typically involve genome-wide genotyping of individuals from a diverse network of ancestries. An important, unsolved problem is how to formulate and estimate probabilistic models of observed genotypes that…

种群与进化 · 定量生物学 2017-01-10 Wei Hao , Minsun Song , John D. Storey

Dynamic event prediction, using joint modeling of survival time and longitudinal variables, is extremely useful in personalized medicine. However, the estimation of joint models including many longitudinal markers is still a computational…

统计方法学 · 统计学 2024-12-13 Reza Hashemi , Taban Baghfalaki , Viviane Philipps , Helene Jacqmin-Gadda

We present a dynamical model of lipoprotein metabolism derived by combining a cascading process in the blood stream and cellular level regulatory dynamics. We analyse the existence and stability of equilibria and show that this…

定量方法 · 定量生物学 2007-05-23 Elias August , Kim H. Parker , Mauricio Barahona

Principal component analysis (PCA) for binary data, known as logistic PCA, has become a popular alternative to dimensionality reduction of binary data. It is motivated as an extension of ordinary PCA by means of a matrix factorization, akin…

机器学习 · 统计学 2020-09-08 Andrew J. Landgraf , Yoonkyung Lee

Longitudinal omics data (LOD) analysis is essential for understanding the dynamics of biological processes and disease progression over time. This review explores various statistical and computational approaches for analyzing such data,…

统计方法学 · 统计学 2025-06-16 Ali R. Taheriyoun , Allen Ross , Abolfazl Safikhani , Damoon Soudbakhsh , Ali Rahnavard

A key question in clinical practice is accurate prediction of patient prognosis. To this end, nowadays, physicians have at their disposal a variety of tests and biomarkers to aid them in optimizing medical care. These tests are often…

For very large datasets, random projections (RP) have become the tool of choice for dimensionality reduction. This is due to the computational complexity of principal component analysis. However, the recent development of randomized…

机器学习 · 统计学 2019-01-04 Michael Wojnowicz , Di Zhang , Glenn Chisholm , Xuan Zhao , Matt Wolff

Principal component analysis (PCA) is arguably the most widely used approach for large-dimensional factor analysis. While it is effective when the factors are sufficiently strong, it can be inconsistent when the factors are weak and/or the…

统计方法学 · 统计学 2025-08-22 Zhongyuan Lyu , Ming Yuan

Dimensionality reduction on Riemannian manifolds is challenging due to the complex nonlinear data structures. While probabilistic principal geodesic analysis~(PPGA) has been proposed to generalize conventional principal component analysis…

机器学习 · 计算机科学 2019-09-06 Youshan Zhang , Jiarui Xing , Miaomiao Zhang