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We consider a stochastic Hodgkin-Huxley model driven by a periodic signal as model for the membrane potential of a pyramidal neuron. The associated five dimensional diffusion process is a time inhomogeneous highly degenerate diffusion for…

概率论 · 数学 2012-07-03 Reinhard Höpfner , Eva Löcherbach , Michèle Thieullen

The stochastic Hodgkin-Huxley neurons considered in this paper replace time-constant deterministic input $a dt$ of the classical deterministic model by increments $\vartheta dt + dX_t$ of a stochastic process: $X$ is Ornstein-Uhlenbeck with…

概率论 · 数学 2023-06-22 Reinhard Höpfner

In this paper, we analyze the use of the Ornstein-Uhlenbeck process to model dynamical systems subjected to bounded noisy perturbations. In order to discuss the main characteristics of this new approach we consider some basic models in…

We discuss estimation problems where a polynomial is observed under Ornstein Uhlenbeck noise over a long time interval. We prove local asymptotic normality (LAN) and specify asymptotically efficient estimators. We apply this to the…

概率论 · 数学 2020-03-31 Reinhard Höpfner

We consider a classical space-clamped Hodgkin-Huxley model neuron stimulated by synaptic excitation and inhibition with conductances represented by Ornstein-Uhlenbeck processes. Using numerical solutions of the stochastic model system…

神经元与认知 · 定量生物学 2016-04-19 Henry C. Tuckwell , Susanne Ditlevsen

We formulate simple criteria for positive Harris recurrence of strongly degenerate stochastic differential equations with smooth coefficients when the drift depends on time and space and is periodic in the time argument. There is no time…

概率论 · 数学 2016-04-11 R. Höpfner , E. Löcherbach , M. Thieullen

We prove some efficient inference results concerning estimation of a Ornstein-Uhlenbeck regression model, which is driven by a non-Gaussian stable Levy process and where the output process is observed at high-frequency over a fixed time…

统计理论 · 数学 2023-01-18 Hiroki Masuda

In recent years, many difficulties appeared when taking into account the inherent stochastic behavior of neurons and voltage-dependent ion channels in Hodgking-Huxley type models. In particular, an open problem for a stochastic model of…

动力系统 · 数学 2012-09-21 Jacky Cresson , Bénédicte Puig , Stefanie Sonner

We propose a new approach to constructing a neural network for predicting expectations of stochastic differential equations. The proposed method does not need data sets of inputs and outputs; instead, the information obtained from the…

机器学习 · 计算机科学 2023-09-13 Naoki Sugishita , Jun Ohkubo

The Hodgkin and Huxley (H-H) model is a nonlinear system of four equations that describes how action potentials in neurons are initiated and propagated, and represents a major advance in the understanding of nerve cells. However, some of…

数值分析 · 数学 2019-03-26 Jemy A. Mandujano Valle , Alexandre L. Madureira

In this paper we study the existence of densities for strongly degenerate stochastic differential equations (SDEs) whose coefficients depend on time and are not globally Lipschitz. In these models neither local ellipticity nor the strong…

概率论 · 数学 2014-10-02 Reinhard Höpfner , E. Löcherbach , M. Thieullen

We consider a fractional Ornstein-Uhlenbeck process involving a stochastic forcing term in the drift, as a solution of a linear stochastic differential equation driven by a fractional Brownian motion. For such process we specify mean and…

概率论 · 数学 2020-09-25 Giacomo Ascione , Yuliya Mishura , Enrica Pirozzi

The Hodgkin-Huxley (HH) model is the currently accepted formalism of neuronal excitability. However, the HH model does not capture a number of biophysical behaviors associated with action potentials or propagating nerve impulses. Physical…

神经元与认知 · 定量生物学 2015-06-17 Jerel Mueller , William J. Tyler

Noise aids the encoding of continuous signals into pulse sequences by way of stochastic resonance and endows the encoding device with a preferred frequency. We study encoding by a threshold device based on the Ornstein-Uhlenbeck process,…

生物物理 · 物理学 2007-05-23 Hans E. Plesser , Theo Geisel

The model studied in this paper is a stochastic extension of the so-called neuron model introduced by Hodgkin and Huxley. In the sense of rough paths, the model is perturbed by a multiplicative noise driven by a fractional Brownian motion,…

概率论 · 数学 2019-10-15 Laure Coutin , Jean-Marc Guglielmi , Nicolas Marie

We combine earlier investigations of linear systems with L\'{e}vy fluctuations [Physica {\bf 113A}, 203, (1982)] with recent discussions of L\'{e}vy flights in external force fields [Phys.Rev. {\bf E 59},2736, (1999)]. We give a complete…

chao-dyn · 物理学 2015-06-24 Piotr Garbaczewski , Robert Olkiewicz

We consider a multidimensional time-homogeneous dynamical system and add a randomly perturbed time-dependent deterministic signal to some of its components, giving rise to a high-dimensional system of stochastic differential equations,…

概率论 · 数学 2019-08-02 Simon Holbach

In this work, we study the class of stochastic process that generalizes the Ornstein-Uhlenbeck processes, hereafter called by \emph{Generalized Ornstein-Uhlenbeck Type Process} and denoted by GOU type process. We consider them driven by the…

统计理论 · 数学 2021-08-17 J. Stein , S. R. C. Lopes , A. V. Medino

Learning is a fundamental property of intelligent systems, observed across biological organisms and engineered systems. While modern intelligent systems typically rely on gradient descent for learning, the need for exact gradients and…

机器学习 · 计算机科学 2024-12-10 Jesus Garcia Fernandez , Nasir Ahmad , Marcel van Gerven

In the paper we consider the problem of estimating parameters entering the drift of a fractional Ornstein-Uhlenbeck type process in the non-ergodic case, when the underlying stochastic integral is of Young type. We consider the sampling…

概率论 · 数学 2019-03-20 Radomyra Shevchenko , Jeannette H. C. Woerner
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