相关论文: Reconstructing Roma history from genome-wide data
Gene gains and losses have shaped the gene repertoire of species since the universal last common ancestor to species today. Genes in extant species were gained at different historical times via de novo creation of new genes, duplication of…
Italian is a Romance language that has its roots in Vulgar Latin. The birth of the modern Italian started in Tuscany around the 14th century, and it is mainly attributed to the works of Dante Alighieri, Francesco Petrarca and Giovanni…
Nicholls and Gray (2008) describe a phylogenetic model for trait data. They use their model to estimate branching times on Indo-European language trees from lexical data. Alekseyenko et al. (2008) extended the model and give applications in…
The methodological issues and statistical complexities of analyzing university students with migrant backgrounds is explored, focusing on Italian data from the University of Milano-Bicocca. With the increasing size of migrant populations…
An integrated and widespread road system, like the one built during the Roman Empire in Italy, plays an important role today in facilitating the construction of new infrastructure. This paper investigates the historical path of Roman roads…
The Genographic Project is an international effort using genetic data to chart human migratory history. The project is non-profit and non-medical, and through its Legacy Fund supports locally led efforts to preserve indigenous and…
Mendez et al. recently report the identification of a Y chromosome lineage from an African American that is an outgroup to all other known Y haplotypes, and report a time to most recent common ancestor, TMRCA, for human Y lineages that is…
Computational approaches to historical linguistics have been proposed since half a century. Within the last decade, this line of research has received a major boost, owing both to the transfer of ideas and software from computational…
Human populations have a complex history of introgression and of changing population size. Human genetic variation has been affected by both these processes, so that inference of past population size depends upon the pattern of gene flow…
Biological cells replicate their genomes in a well-planned manner. The DNA replication program of an organism determines the timing at which different genomic regions are replicated, with fundamental consequences for cell homeostasis and…
The birth of new genes is an important motor of evolutionary innovation. Whereas many new genes arise by gene duplication, others originate at genomic regions that do not contain any gene or gene copy. Some of these newly expressed genes…
Human history leaves fingerprints in human languages. Little is known over language evolution and its study is of great importance. Here, we construct a simple stochastic model and compare its results to statistical data of real languages.…
Horseshoe crabs are marine arthropods with a fossil record extending back approximately 450 million years. They exhibit remarkable morphological stability over their long evolutionary history, retaining a number of ancestral arthropod…
Myopia, or nearsightedness, is the most common eye disorder, resulting primarily from excess elongation of the eye. The etiology of myopia, although known to be complex, is poorly understood. Here we report the largest ever genome-wide…
Spoken language datasets are vital for advancing linguistic research, Natural Language Processing, and speech technology. However, resources dedicated to Italian, a linguistically rich and diverse Romance language, remain underexplored…
Large scale databases are available that contain homologous gene families constructed from hundreds of complete genome sequences from across the three domains of Life. Here we discuss approches of increasing complexity aimed at extracting…
A common sample descriptor in human genomics studies is that of 'genetic ancestry group', with terms such as 'European genetic ancestry' or 'East Asian genetic ancestry' frequently used in publications to describe the genetics of groups of…
The Human Genome Project (HGP) provides researchers with the data of nearly all human genes and the challenge to use this information for elucidating the etiology of common disorders. A secondary Darwinian method was applied to HGP and…
Many Mendelian randomization (MR) papers have been conducted only in people of European ancestry, limiting transportability of results to the global population. Expanding MR to diverse ancestry groups is essential to ensure equitable…
We linked names and contact information to publicly available profiles in the Personal Genome Project. These profiles contain medical and genomic information, including details about medications, procedures and diseases, and demographic…