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Over the last years, increasing evidence has fuelled the hypothesis that Autism Spectrum Disorder (ASD) is a condition of altered brain functional connectivity. The great majority of these empirical studies rely on functional magnetic…

神经元与认知 · 定量生物学 2010-08-02 Pablo Barttfeld , Bruno Wicker , Sebastián Cukier , Silvana Navarta , Sergio Lew , Mariano Sigman

Today the human brain can be modeled as a graph where nodes represent different regions and links stand for statistical interactions between their activities as recorded by different neuroimaging techniques. Empirical studies have lead to…

神经元与认知 · 定量生物学 2017-11-01 J. H. Martínez , J. M. Buldú , D. Papo , F. De Vico Fallani , M. Chavez

We investigate interaction networks that we derive from multivariate time series with methods frequently employed in diverse scientific fields such as biology, quantitative finance, physics, earth and climate sciences, and the…

数据分析、统计与概率 · 物理学 2012-01-10 Stephan Bialonski , Martin Wendler , Klaus Lehnertz

The neuromagnetic activity (magnetoencephalogram, MEG) from healthy human brain and from an epileptic patient against chromatic flickering stimuli has been earlier analyzed on the basis of a memory functions formalism (MFF). Information…

医学物理 · 物理学 2010-06-29 O. Yu. Panischev , S. A. Demin , J. Bhattacharya

We construct embedded functional connectivity networks (FCN) from benchmark resting-state functional magnetic resonance imaging (rsfMRI) data acquired from patients with schizophrenia and healthy controls based on linear and nonlinear…

神经元与认知 · 定量生物学 2023-03-24 Ioannis Gallos , Evangelos Galaris , Constantinos Siettos

In recent years, network analyses have been used to evaluate brain reorganization following stroke. However, many studies have often focused on single topological scales, leading to an incomplete model of how focal brain lesions affect…

The brain's structural and functional systems, protein-protein interaction, and gene networks are examples of biological systems that share some features of complex networks, such as highly connected nodes, modularity, and small-world…

Typical brain networks consist of many peripheral regions and a few highly central ones, i.e. hubs, playing key functional roles in cerebral inter-regional interactions. Studies have shown that networks, obtained from the analysis of…

神经元与认知 · 定量生物学 2016-07-19 Manlio De Domenico , Shuntaro Sasai , Alex Arenas

A brain wide association study (BWAS) based on the logistic regression was first developed and applied to a large population of epilepsy patients (168) and healthy controls (136). It was found that the most significant links associated with…

医学物理 · 物理学 2012-09-26 Wei Cheng , Xuejuan Zhang , Ge Tian , Jianfeng Feng , Zhengge Wang , Zhiqiang Zhang , GuangMing Lu

Functional connectivity (FC) studies have demonstrated the overarching value of studying the brain and its disorders through the undirected weighted graph of fMRI correlation matrix. Most of the work with the FC, however, depends on the way…

神经元与认知 · 定量生物学 2021-12-09 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis

Spectral networks derived from multivariate time series data arise in many domains, from brain science to Earth science. Often, it is of interest to study how these networks change under different conditions. For instance, to better…

统计方法学 · 统计学 2025-07-22 Michael Hellstern , Byol Kim , Zaid Harchaoui , Ali Shojaie

We assess electrical brain dynamics before, during, and after one-hundred human epileptic seizures with different anatomical onset locations by statistical and spectral properties of functionally defined networks. We observe a concave-like…

神经元与认知 · 定量生物学 2013-11-25 Kaspar A. Schindler , Stephan Bialonski , Marie-Therese Horstmann , Christian E. Elger , Klaus Lehnertz

The study's objective is to explore the distinctions in the functional brain network connectivity between Alzheimer's Disease (AD) patients and normal controls using Functional Magnetic Resonance Imaging (fMRI). The study included 590…

神经元与认知 · 定量生物学 2023-05-17 Yongcheng Yao

One notable method for recording brainwaves to identify neurological problems is electroencephalography (hereafter EEG). A trained neuro physician can learn more about how the brain functions through the use of EEGs. However conventionally,…

神经元与认知 · 定量生物学 2024-02-26 Hari Prasad SV

Deep reinforcement learning (DRL) algorithms have the potential to provide new insights into psychiatric disorders. Here we create a DRL model of schizophrenia: a complex psychotic disorder characterized by anhedonia, avoidance, temporal…

神经元与认知 · 定量生物学 2025-10-30 Xena Al-Hejji , Santina Duarte , Jose Guillermo Gomez Castro , Edgar Bermudez Contreras , Eric Chalmers

The human neocortex is functionally organised at its highest level along a continuous sensory-to-association (AS) hierarchy. This study characterises the AS hierarchy of patients with schizophrenia in a comparison with controls. Using a…

神经元与认知 · 定量生物学 2025-11-06 Subati Abulikemu , Puria Radmard , Michail Mamalakis , John Suckling

Functional connectivity (FC) has been widely used to study brain network interactions underlying the emerging cognition and behavior of an individual. FC is usually defined as the correlation or partial correlation between brain regions.…

应用统计 · 统计学 2020-10-27 Gemeng Zhang , Aiying Zhang , Biao Cai , Zhuozhuo Tu , Vince D. Calhoun , Yu-Ping Wang

In spite of years of research, the mechanisms that underlie the development of schizophrenia, as well as its relapse, symptomatology, and treatment, continue to be a mystery. The absence of appropriate analytic tools to deal with the…

计算机视觉与模式识别 · 计算机科学 2022-10-12 Vigneshwaran Shankaran , Bhaskaran V

We explore how to study dynamical interactions between brain regions using functional multilayer networks whose layers represent the different frequency bands at which a brain operates. Specifically, we investigate the consequences of…

神经元与认知 · 定量生物学 2017-09-15 Javier M. Buldú , Mason A. Porter

Epilepsy is a network disease. The epileptic network usually involves spatially distributed brain regions. In this context, noninvasive M/EEG source connectivity is an emerging technique to identify functional brain networks at cortical…

神经元与认知 · 定量生物学 2016-08-18 Mahmoud Hassan , Isabelle Merlet , Ahmad Mheich , Aya Kabbara , Arnaud Biraben , Anca Nica , Fabrice Wendling