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A theoretical study is presented to quantitatively analyze the transport experiment through individual DNA molecules reported recently by Porath {\it et al.} [Nature {\bf 403}, 635 (2000)]. A variety of valuable quantities are identified by…

介观与纳米尺度物理 · 物理学 2009-11-07 Xin-Qi Li , YiJing Yan

Superconductivity occurs in electrochemically doped molybdenum dichalcogenides samples thicker than four layers. While the critical temperature (Tc) strongly depends on the field effect geometry (single or double gate) and on the sample…

超导电性 · 物理学 2022-11-28 Giovanni Marini , Matteo Calandra

Plectonemes are intertwined helically looped domains which form when a DNA molecule is supercoiled, i.e. over- or under-wounded. They are ubiquitous in cellular DNA and their physical properties have attracted significant interest both from…

软凝聚态物质 · 物理学 2022-09-14 Enrico Skoruppa , Enrico Carlon

DNA torsion dynamics is essential in the transcription process; simple models for it have been proposed by several authors, in particular Yakushevich (Y model). These are strongly related to models of DNA separation dynamics such as the one…

生物大分子 · 定量生物学 2009-11-13 Mariano Cadoni , Roberto De Leo , Sergio Demelio , Giuseppe Gaeta

We propose that semiflexible polymers in poor solvent collapse in two stages. The first stage is the well known formation of a dense toroidal aggregate. However, if the solvent is sufficiently poor, the condensate will undergo a second…

软凝聚态物质 · 物理学 2009-11-10 Igor M. Kulic , Denis Andrienko , Markus Deserno

Modeling charge transport in DNA is essential to understand and control the electrical properties and develop DNA-based nanoelectronics. DNA is a fluctuating molecule that exists in a solvent environment, which makes the electron…

生物物理 · 物理学 2023-10-05 Hashem Mohammad , M. P. Anantram

This paper introduces the use of cable dynamics models as a means to explore the mechanics of DNA on long-length scales. It is on these length scales that DNA forms twisted and curved three-dimensional shapes known as supercoils and loops.…

生物物理 · 物理学 2007-05-23 Sachin Goyal , Todd Lillian , Noel C. Perkins , Edgar Meyhofer

We study the static and dynamical properties of DNA in the vicinity of its melting transition, i.e. the separation of the two strands upon heating. The investigation is based on a simple mechanical model which includes the helicoidal…

统计力学 · 物理学 2007-06-19 Maria Barbi , Stefano Lepri , Michel Peyrard , Nikos Theodorakopoulos

Recently the physical characterization of a number of biological processes has proven indispensable for a full understanding of natural phenomena. One such example is the mechanical properties of transcription, which have been shown to have…

亚细胞过程 · 定量生物学 2017-07-05 Stuart A. Sevier , Herbert Levine

We report studies of the equilibrium and the dynamics of a general set of lattice models which capture the essence of the force-induced or mechanical DNA unzipping transition. Besides yielding the whole equilibrium phase diagram in the…

软凝聚态物质 · 物理学 2009-11-07 D. Marenduzzo , S. M. Bhattacharjee , A. Maritan , E. Orlandini , F. Seno

Single molecule experiments on B-DNA stretching have revealed one or two structural transitions, when increasing the external force. They are characterized by a sudden increase of DNA contour length and a decrease of the bending rigidity.…

软凝聚态物质 · 物理学 2012-10-25 Manoel Manghi , Nicolas Destainville , John Palmeri

Motivated by recent experiments, we develop a model for DNA toroids under external tension. We find that tori are the equilibrium states for our model up to a critical tension, above which they become only metstable. Above this tension, we…

生物物理 · 物理学 2013-05-29 C. Battle , B. van den Broek , M. C. Noom , J. van Mameren , G. J. L. Wuite , F. C. MacKintosh

To study the elastic properties of rod-like DNA nanostructures, we perform long simulations of these structure using the oxDNA coarse-grained model. By analysing the fluctuations in these trajectories we obtain estimates of the bend and…

We study the effects of the shear force on the rupture mechanism on a double stranded DNA. Motivated by recent experiments, we perform the atomistic simulations with explicit solvent to obtain the distributions of extension in hydrogen and…

软凝聚态物质 · 物理学 2015-06-17 S. Nath , T. Modi , R. K. Mishra , D. Giri , B. P. Mandal , S. Kumar

Transmission of electrons across a rectangular barrier of IV-VI semiconductor compounds is considered. Conduction electrons arrive at the barrier and are reflected or transmitted through it depending on the relative values of the barrier…

介观与纳米尺度物理 · 物理学 2021-05-26 P. Pfeffer , W. Zawadzki , K. Dybko

The macroscopic curvature of double helical DNA induced by regularly repeated adenine tracts is well-known but still puzzling. Its physical origin remains controversial even though it is perhaps the best-documented sequence modulation of…

生物物理 · 物理学 2007-05-23 Alexey K. Mazur , Dimitri E. Kamashev

A theoretical model which takes into account the structural distortion of double-crossover DNA tiles has been studied to investigate its effect on lattice formation sizes. It has been found that a single vector appropriately describes the…

介观与纳米尺度物理 · 物理学 2011-05-12 Seungjae Kim , Junghoon Kim , Pengfei Qian , Jihoon Shin , Rashid Amin , Sang Jung Ahn , Thomas H. LaBean , Moon Ki Kim , Sung Ha Park

In this work we numerically calculate the electric current through three kinds of DNA sequences (telomeric, \lambda-DNA, and p53-DNA) described by different heuristic models. A bias voltage is applied between two zig-zag edged graphene…

介观与纳米尺度物理 · 物理学 2012-10-02 Carlos J. Páez , Peter A. Schulz , Neil Wilson , Rudolf A. Römer

The Tethered Particle Motion (TPM) technique informs about conformational changes of DNA molecules, e.g. upon looping or interaction with proteins, by tracking the Brownian motion of a particle probe tethered to a surface by a single DNA…

The binding of proteins onto DNA contributes to the shaping and packaging of genome as well as to the expression of specific genetic messages. With a view to understanding the interplay between the presence of proteins and the deformation…

生物物理 · 物理学 2014-05-30 Nicolas Clauvelin , Wilma K. Olson
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