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We consider applying Bayesian Variable Selection Regression, or BVSR, to genome-wide association studies and similar large-scale regression problems. Currently, typical genome-wide association studies measure hundreds of thousands, or…

应用统计 · 统计学 2011-10-28 Yongtao Guan , Matthew Stephens

We consider the problem of sparse signal recovery from noisy measurements. Many of frequently used recovery methods rely on some sort of tuning depending on either noise or signal parameters. If no estimates for either of them are…

信息论 · 计算机科学 2020-10-20 Hendrik Bernd Petersen , Peter Jung

In this paper we present a linear programming solution for sign pattern recovery of a sparse signal from noisy random projections of the signal. We consider two types of noise models, input noise, where noise enters before the random…

信息论 · 计算机科学 2015-03-13 V. Saligrama , M. Zhao

Large-scale replication studies like the Reproducibility Project: Psychology (RP:P) provide invaluable systematic data on scientific replicability, but most analyses and interpretations of the data fail to agree on the definition of…

统计方法学 · 统计学 2022-03-08 Kenneth Hung , William Fithian

The estimation of causal treatment effects from observational data is a fundamental problem in causal inference. To avoid bias, the effect estimator must control for all confounders. Hence practitioners often collect data for as many…

机器学习 · 统计学 2020-11-05 Kristjan Greenewald , Dmitriy Katz-Rogozhnikov , Karthik Shanmugam

We present a statistical framework to benchmark the performance of reconstruction algorithms for linear inverse problems, in particular, neural-network-based methods that require large quantities of training data. We generate synthetic…

信号处理 · 电气工程与系统科学 2023-07-05 Pakshal Bohra , Pol del Aguila Pla , Jean-François Giovannelli , Michael Unser

As a popular tool for producing meaningful and interpretable models, large-scale sparse learning works efficiently when the underlying structures are indeed or close to sparse. However, naively applying the existing regularization methods…

统计方法学 · 统计学 2017-10-10 Zemin Zheng , Jinchi Lv , Wei Lin

We propose a class of greedy algorithms for weighted sparse recovery by considering new loss function-based generalizations of Orthogonal Matching Pursuit (OMP). Given a (regularized) loss function, the proposed algorithms alternate the…

信息论 · 计算机科学 2025-02-18 Sina Mohammad-Taheri , Simone Brugiapaglia

Propensity Score Matching (PSM) is an useful method to reduce the impact ofTreatment - Selection Bias in the estimation of causal effects in observational studies. After matching, the PSM significantly reduces the sample under…

统计方法学 · 统计学 2019-02-01 Daniel García Iglesias

For the vast majority of genome wide association studies (GWAS) published so far, statistical analysis was performed by testing markers individually. In this article we present some elementary statistical considerations which clearly show…

应用统计 · 统计学 2010-10-04 Florian Frommlet , Felix Ruhaltinger , Piotr Twarog , Malgorzata Bogdan

Automated model discovery of partial differential equations (PDEs) usually considers a single experiment or dataset to infer the underlying governing equations. In practice, experiments have inherent natural variability in parameters,…

机器学习 · 统计学 2021-11-25 Georges Tod , Gert-Jan Both , Remy Kusters

Compressed sensing has a wide range of applications that include error correction, imaging, radar and many more. Given a sparse signal in a high dimensional space, one wishes to reconstruct that signal accurately and efficiently from a…

数值分析 · 数学 2009-05-28 Deanna Needell

We study a generalized framework for structured sparsity. It extends the well-known methods of Lasso and Group Lasso by incorporating additional constraints on the variables as part of a convex optimization problem. This framework provides…

机器学习 · 计算机科学 2011-06-28 Andreas Argyriou , Luca Baldassarre , Jean Morales , Massimiliano Pontil

High-dimensional learning problems, where the number of features exceeds the sample size, often require sparse regularization for effective prediction and variable selection. While established for fully supervised data, these techniques…

机器学习 · 计算机科学 2026-01-01 The Tien Mai , Mai Anh Nguyen , Trung Nghia Nguyen

Many imaging science tasks can be modeled as a discrete linear inverse problem. Solving linear inverse problems is often challenging, with ill-conditioned operators and potentially non-unique solutions. Embedding prior knowledge, such as…

数值分析 · 数学 2023-12-07 Elizabeth Newman , Jack Michael Solomon , Matthias Chung

Parsimony in signal representation is a topic of active research. Sparse signal processing and representation is the outcome of this line of research which has many applications in information processing and has shown significant…

计算机视觉与模式识别 · 计算机科学 2018-05-15 Hojjat Seyed Mousavi

Rapid development of sparse sampling methodology offers dramatic increase in power and efficiency of magnetic resonance techniques in medicine, chemistry, molecular structural biology, and other fields. We suggest to use available yet…

化学物理 · 物理学 2014-01-28 Maxim Mayzel , Krzysztof Kazimierczuk , Vladislav Yu. Orekhov

Sparse estimation methods are aimed at using or obtaining parsimonious representations of data or models. They were first dedicated to linear variable selection but numerous extensions have now emerged such as structured sparsity or kernel…

机器学习 · 计算机科学 2011-11-24 Francis Bach , Rodolphe Jenatton , Julien Mairal , Guillaume Obozinski

In this paper, association results from genome-wide association studies (GWAS) are combined with a deep learning framework to test the predictive capacity of statistically significant single nucleotide polymorphism (SNPs) associated with…

计算机与社会 · 计算机科学 2018-08-27 Casimiro Adays Curbelo Montañez , Paul Fergus , Almudena Curbelo Montañez , Carl Chalmers

Sparse recovery in linear systems underpins applications from signal processing to high-dimensional regression. Sparse Bayesian Learning, grounded in the principle of automatic relevance determination (ARD), offers a practical Bayesian…