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Persistence and permanence are properties of dynamical systems that describe the long-term behavior of the solutions, and in particular specify whether positive solutions approach the boundary of the positive orthant. Mass-action systems…

动力系统 · 数学 2011-03-03 Gheorghe Craciun , Fedor Nazarov , Casian Pantea

The persistence conjecture is a long-standing open problem in chemical reaction network theory. It concerns the behavior of solutions to coupled ODE systems that arise from applying mass-action kinetics to a network of chemical reactions.…

动力系统 · 数学 2014-10-07 Abhishek Deshpande , Manoj Gopalkrishnan

Systems of differential equations with polynomial right-hand sides are very common in applications. In particular, when restricted to the positive orthant, they appear naturally (according to the law of mass-action kinetics) in ecology,…

动力系统 · 数学 2023-03-06 Gheorghe Craciun , Abhishek Deshpande , Jiaxin Jin

In this paper we show that the dynamics of a class of kinetic compartmental models with bounded capacities, monotone reaction rates and a strongly connected interconnection structure is persistent. The result is based on the chemical…

动力系统 · 数学 2022-01-25 G. Szederkenyi , B. Acs , Gy. Liptak , M. A. Vaghy

This paper concerns the long-term behavior of population systems, and in particular of chemical reaction systems, modeled by deterministic mass-action kinetics. We approach two important open problems in the field of Chemical Reaction…

动力系统 · 数学 2012-03-21 Casian Pantea

A natural condition on the structure of the underlying chemical reaction network, namely weak reversibility, is shown to guarantee the existence of an equilibrium (steady state) in each positive stoichiometric compatibility class for the…

定量方法 · 定量生物学 2011-11-14 Jian Deng , Christopher Jones , Martin Feinberg , Adrian Nachman

Homeostasis occurs in a biological system when a chosen output variable remains approximately constant despite changes in an input variable. In this work we specifically focus on biological systems which may be represented as chemical…

定量方法 · 定量生物学 2024-07-19 Jiaxin Jin , Grzegorz A. Rempala

We show that weakly reversible mass-action systems can have a continuum of positive steady states, coming from the zeroes of a multivariate polynomial. Moreover, the same is true of systems whose underlying reaction network is reversible…

分子网络 · 定量生物学 2022-09-14 Balázs Boros , Gheorghe Craciun , Polly Y. Yu

We establish that mass conserving single terminal-linkage networks of chemical reactions admit positive steady states regardless of network deficiency and the choice of reaction rate constants. This result holds for closed systems without…

分子网络 · 定量生物学 2015-03-19 Santiago Akle , Onkar Dalal , Ronan M. T. Fleming , Michael Saunders , Nicole Taheri , Yinyu Ye

With the increasing complexity of time-delayed systems, the diversification of boundary types of chemical reaction systems poses a challenge for persistence analysis. This paper focuses on delayed complex balanced mass action systems…

动力系统 · 数学 2023-03-29 Xiaoyu Zhang , Chuanhou Gao , Denis Dochain

The notion of a part of phase space containing desired (or allowed) states of a dynamical system is important in a wide range of complex systems research. It has been called the safe operating space, the viability kernel or the sunny…

适应与自组织系统 · 物理学 2016-07-15 Frank Hellmann , Paul Schultz , Carsten Grabow , Jobst Heitzig , Jürgen Kurths

Persistency is the property, for differential equations in $\R^n$, that solutions starting in the positive orthant do not approach the boundary. For chemical reactions and population models, this translates into the non-extinction property:…

分子网络 · 定量生物学 2007-05-23 David Angeli , Patrick De Leenheer , Eduardo Sontag

We study semi-dynamical systems associated to delay differential equations. We give a simple criteria to obtain weak and strong persistence and provide sufficient conditions to guarantee uniform persistence. Moreover, we show the existence…

经典分析与常微分方程 · 数学 2020-02-04 Pablo Amster , Melanie Bondorevsky

We consider the Nernst-Planck-Stokes system on a bounded domain of $\mathbb{R}^d$, $d=2,3$ with general nonequilibrium Dirichlet boundary conditions for the ionic concentrations. It is well known that, in a wide range of cases, equilibrium…

偏微分方程分析 · 数学 2025-01-09 Fizay-Noah Lee

Living systems are forced away from thermodynamic equilibrium by exchange of mass and energy with their environment. In order to model a biochemical reaction network in a non-equilibrium state one requires a mathematical formulation to…

分子网络 · 定量生物学 2012-02-21 Ronan M. T. Fleming , Ines Thiele

The Deficiency-One Theorem states that there exists a unique positive steady state in each positive stoichiometric class for weakly reversible deficiency-one mass action systems with one linkage class (regardless of the values of the rate…

动力系统 · 数学 2022-09-14 Balázs Boros

We give a new proof of the fact that each weakly reversible mass-action system with a single linkage class is permanent.

动力系统 · 数学 2022-09-14 Balázs Boros , Josef Hofbauer

Persistence is an important characteristic of many complex systems in nature, related to how long the system remains at a certain state before changing to a different one. The study of complex systems' persistence involves different…

We consider two non-interacting systems embedded in a heat bath. If they remain dynamically independent, physical inconsistencies are avoided only if the single-system reduced dynamics is completely positive also beyond the weak-coupling…

量子物理 · 物理学 2015-06-26 F. Benatti , R. Floreanini

A class of distributed systems with a cyclic interconnection structure is considered. These systems arise in several biochemical applications and they can undergo diffusion driven instability which leads to a formation of spatially…

最优化与控制 · 数学 2007-05-23 M. R. Jovanovic , M. Arcak , E. D. Sontag
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