相关论文: Statistical analysis on detecting recombination si…
We have used whole genome paired-end Illumina sequence data to identify tandem duplications in 20 isofemale lines of D. yakuba, and 20 isofemale lines of D. simulans and performed genome wide validation with PacBio long molecule sequencing.…
We propose a model to explain the reduced bimolecular recombination rate found in state-of-the-art bulk heterojunction solar cells. When compared to the Langevin recombination, the experimentally observed rate is one to four orders of…
The various possibilities for the progenitors of gamma-ray bursts (GRBs) manifest in differing observable properties. Through deep spectroscopic and high-resolution imaging observations of some GRB hosts, I demonstrate that well-localized…
Gamma-ray binaries are thought to be composed of a young pulsar in orbit around a massive O or Be star, with their gamma-ray emission powered by pulsar spindown. The number of such systems in our Galaxy is not known. We aim to estimate the…
The aim of the study is to analyze viruses using parameters obtained from distributions of nucleotide sequences in the viral RNA. Seeking for the input data homogeneity, we analyze single-stranded RNA viruses only. Two approaches are used…
In the classical $\beta$-ensembles of random matrix theory, setting $\beta = 2 \alpha/N$ and taking the $N \to \infty$ limit gives a statistical state depending on $\alpha$. Using the loop equations for the classical $\beta$-ensembles, we…
An important aspect of many botnets is their capability to generate pseudorandom domain names using Domain Generation Algorithms (DGAs). A cyber criminal can register such domains to establish periodically changing rendezvous points with…
In the current work, we study the eigenvalue distribution results of a class of non-normal matrix-sequences which may be viewed as a low rank perturbation, depending on a parameter $\beta>1$, of the basic Toeplitz matrix-sequence…
We propose a scar model to reproduce how double-strand breaks occur in the telomeric DNA damaged by the effect of the $\beta$-decay of tritium to helium. In this scar model, the two hydrogens bonded to the 5$^\prime$ carbon connecting the…
The dynamics of recombination in genetics leads to an interesting nonlinear differential equation, which has a natural generalization to a measure valued version. The latter can be solved explicitly under rather general circumstances. It…
The target theory is the most classical hypothesis explaining radiation-induced cell death, the physical or biological nature of the "target" remains ambiguous. This study hypothesizes that the distribution of DNA double-strand breaks…
When estimating a phylogeny from a multiple sequence alignment, researchers often assume the absence of recombination. However, if recombination is present, then tree estimation and all downstream analyses will be impacted, because…
We have analyzed the relations between the mutational pressure, recombination and selection pressure in the bit-string model with sexual reproduction. For specific sets of these parameters we have found three phase transitions with one…
We review experimental and theoretical efforts aimed at a detailed understanding of the recombination of electrons with highly-charged tungsten ions characterised by an open 4f sub-shell. Highly-charged tungsten occurs as a plasma…
Let $\beta$ be any permutation on $n$ symbols and let $c(k, \beta)$ be the number of permutations that $k$-commute with $\beta$. The cycle type of a permutation $\beta$ is a vector $(c_1, \dots, c_n)$ such that $\beta$ has exactly $c_i$…
Intracellular transport of DNA carriers is a fundamental step of gene delivery. We present here a theoretical approach to study generically a single virus or DNA particle trafficking in a cell cytoplasm. Cellular trafficking has been…
With the booming of next generation sequencing technology and its implementation in clinical practice and life science research, the need for faster and more efficient data analysis methods becomes pressing in the field of sequencing. Here…
The base pair fluctuations and helix untwisting are examined for a circular molecule. A realistic mesoscopic model including twisting degrees of freedom and bending of the molecular axis is proposed. The computational method, based on path…
Genetic mutations are footprints of tumour growth. While mutation data in bulk samples has been used to infer evolutionary parameters hard to measure in vivo, the advent of single-cell data has led to strong interest in the mutational…
In studying encounters between binaries and single stars, one is interested in three classes of events: exchanges of stars, hardening of the original binary by a third star, and the production of merged objects. We present a means for…