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Cross-linked filament bundles, such as in cilia and flagella, are ubiquitous in biology. They are considered in textbooks as simple filaments with larger stiffness. Recent observations of flagellar counterbend, however, show that induction…

生物物理 · 物理学 2017-03-14 Rachel Coy , Hermes Gadelha

We elucidate the elastic behavior of a wormlike chain in 3D under compression and provide exact solutions for the experimentally accessible force-extension relation in terms of generalized spheroidal wave functions. In striking contrast to…

软凝聚态物质 · 物理学 2019-11-11 Christina Kurzthaler

By exploring a recent model [Palmeri, J., M. Manghi, and N. Destainville. 2007. Phys. Rev. Lett. 99:088103] where DNA bending elasticity, described by the wormlike chain model, is coupled to base-pair denaturation, we demonstrate that small…

统计力学 · 物理学 2010-06-22 Nicolas Destainville , Manoel Manghi , John Palmeri

A weak fluctuating magnetic field embedded into a turbulent conducting medium grows exponentially while its characteristic scale decays. In the ISM and protogalactic plasmas, the magnetic Pr is very large, so a broad spectrum of growing…

天体物理学 · 物理学 2008-11-26 Alexander Schekochihin , Steven Cowley , Jason Maron , Leonid Malyshkin

It has become clear in recent years that the simple uniform wormlike chain model needs to be modified in order to account for more complex behavior which has been observed experimentally in some important biopolymers. For example, the large…

软凝聚态物质 · 物理学 2017-11-01 Panayotis Benetatos

The dynamics of filaments in flow are central to understanding a wide range of biological and soft-matter systems, yet their behavior under time-dependent forcing remains poorly understood. Here, we investigate the long-time dynamics of…

软凝聚态物质 · 物理学 2026-01-05 Francesco Bonacci , Brato Chakrabarti , Olivia du Roure , Anke Lindner , David Saintillan

DNA cyclization is a powerful technique to gain insight into the nature of DNA bending. The worm-like chain model provides a good description of small to moderate bending fluctuations, but some experiments on strongly-bent shorter molecules…

生物大分子 · 定量生物学 2021-12-03 Ryan M. Harrison , Flavio Romano , Thomas E. Ouldridge , Ard A. Louis , Jonathan P. K. Doye

We study the elastic response of a worm-like polymer chain with reversible kink-like structural defects. This is a generic model for (a) the double-stranded DNA with sharp bends induced by binding of certain proteins, and (b) effects of…

软凝聚态物质 · 物理学 2009-11-10 Yuri O. Popov , Alexei V. Tkachenko

We describe quantitatively a RNA molecule under the influence of an external force exerted at its two ends as in a typical single-molecule experiment. Our calculation incorporates the interactions between nucleotides by using the…

软凝聚态物质 · 物理学 2009-11-07 Ulrich Gerland , Ralf Bundschuh , Terence Hwa

A functional integral formalism is used to derive the extension of a stiff chain subject to an external force. The force versus extension curves are calculated using a meanfield approach in which the hard constraint $u^2(s)=1$ is replaced…

凝聚态物理 · 物理学 2009-10-28 B. -Y. Ha , D. Thirumalai

Exploiting the "natural" frame of space curves, we formulate an intrinsic dynamics of twisted elastic filaments in viscous fluids. A pair of coupled nonlinear equations describing the temporal evolution of the filament's complex curvature…

软凝聚态物质 · 物理学 2009-10-31 Raymond E. Goldstein , Thomas R. Powers , Chris H. Wiggins

The folding transition of biopolymers from the coil to compact structures has attracted wide research interest in the past and is well studied in polymer physics. Recent seminal works on DNA in confined devices have shown that these long…

软凝聚态物质 · 物理学 2023-08-09 Keerthi Radhakrishnan , Sunil P. Singh

We study theoretically the entropic elasticity of a semi-flexible polymer, such as DNA, confined to two dimensions. Using the worm-like-chain model we obtain an exact analytical expression for the partition function of the polymer pulled at…

软凝聚态物质 · 物理学 2009-11-11 Ashok Prasad , Yuko Hori , Jane' Kondev

We propose a formalism for deriving force-elongation and elongation-force relations for flexible chain molecules from analytical expressions for their radial distribution function, which provides insight into the factors controlling the…

软凝聚态物质 · 物理学 2021-02-03 Ralf Everaers , Nils B. Becker , Angelo Rosa

We present a statistical mechanical study of stiff polymers, motivated by experiments on actin filaments and the considerable current interest in polymer networks. We obtain simple, approximate analytical forms for the force-extension…

软凝聚态物质 · 物理学 2009-11-13 Abhijit Ghosh , Joseph Samuel , Supurna Sinha

We develop a novel biased Monte-Carlo simulation technique to measure the force-extension curves and the distribution function of the extension of fluctuating filaments stretched by external force. The method is applicable for arbitrary…

软凝聚态物质 · 物理学 2007-05-23 David A. Kessler , Yitzhak Rabin

We present a novel buckling instability relevant to membrane budding in eukaryotic cells. In this mechanism, curved filaments bind to a lipid bilayer without changing its intrinsic curvature. As more and more filaments adsorb, newly added…

生物物理 · 物理学 2009-07-16 Martin Lenz , Daniel J. G. Crow , Jean-François Joanny

Granular chain packings exhibit a striking emergent strain-stiffening behavior despite the individual looseness of the constitutive chains. Using indentation experiments on such assemblies, we measure an exponential increase in the…

软凝聚态物质 · 物理学 2018-04-02 Denis Dumont , Maurine Houze , Paul Rambach , Thomas Salez , Sylvain Patinet , Pascal Damman

Many of the cell membrane vital functions are achieved by the self-organization of the proteins and biopolymers embedded in it. The protein dynamics are in part determined by its drag. A large number of these proteins can polymerize to form…

流体动力学 · 物理学 2023-09-13 Wenzheng Shi , Moslem Moradi , Ehssan Nazockdast

Aiming at the mechanical properties of cross-linked biopolymers, we set up and analyze a model of two weakly bending wormlike chains subjected to a tensile force, with regularly spaced inter-chain bonds (cross-links) represented by harmonic…

生物物理 · 物理学 2014-06-24 Alice von der Heydt , Daniel Wilkin , Panayotis Benetatos , Annette Zippelius