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A protein undergoes conformational dynamics with multiple time scales, which results in fluctuating enzyme activities. Recent studies in single molecule enzymology have observe this "age-old" dynamic disorder phenomenon directly. However,…

生物大分子 · 定量生物学 2009-11-10 Zhanghan Wu , Vlad Elgart , Hong Qian , Jianhua Xing

Hyperuniformity, whereby the static structure factor (or density correlator) obeys $S(q)\sim q^{\varsigma}$ with $\varsigma> 0$, emerges at criticality in systems having multiple absorbing states, such as periodically sheared suspensions.…

统计力学 · 物理学 2023-10-27 Xiao Ma , Johannes Pausch , Michael E. Cates

By embedding inert tracer particles (TPs) in a growing multicellular spheroid the local stresses on the cancer cells (CCs) can be measured. In order for this technique to be effective the unknown effect of the dynamics of the TPs on the CCs…

生物物理 · 物理学 2020-10-20 Himadri S. Samanta , Sumit Sinha , D. Thirumalai

Activation/deactivation by inelastic collisions have been extensively studied at unimolecular reactions in gas phase where they are crucial for equilibration. As equilibration means an increase of entropy, the mechanism can also be…

统计力学 · 物理学 2011-12-12 Jürgen Schlitter

In this paper we study a two-dimensional directed self-avoiding walk model of a random copolymer in a random emulsion. The copolymer is a random concatenation of monomers of two types, $A$ and $B$, each occurring with density 1/2. The…

概率论 · 数学 2009-11-13 Frank den Hollander , Nicolas Pétrélis

Reversible electropermeabilization, commonly referred to as electroporation, is a transient increase in cell membrane permeability induced by short, high-voltage electric pulses. We present a stochastically perturbed version of a…

偏微分方程分析 · 数学 2026-04-14 Tobias Gebäck , Oleksandr Misiats , Ioanna Motschan-Armen , Irina Pettersson

Active solids consist of elastically coupled out-of-equilibrium units performing work. They are central to autonomous processes, such as locomotion, self-oscillations and rectification, in biological systems,designer materials and robotics.…

软凝聚态物质 · 物理学 2025-01-17 P. Baconnier , D. Shohat , C. Hernandèz , C. Coulais , V. Démery , G. Düring , O. Dauchot

In this paper we propose a nonlinear elasticity model of macromolecular conformational change (deformation) induced by electrostatic forces generated by an implicit solvation model. The Poisson-Boltzmann equation for the electrostatic…

偏微分方程分析 · 数学 2010-01-12 Yongcheng Zhou , Michael Holst , James Andrew McCammon

Electron-positron interactions have been utilized in various fields of science. Here we develop time-dependent multi-component density functional theory to study the coupled electron-positron dynamics from first principles. We prove that…

化学物理 · 物理学 2018-10-03 Yasumitsu Suzuki , Satoshi Hagiwara , Kazuyuki Watanabe

We review the depinning and nonequilibrium phases of collectively interacting particle systems driven over random or periodic substrates. This type of system is relevant to vortices in type-II superconductors, sliding charge density waves,…

超导电性 · 物理学 2017-12-06 C. Reichhardt , C. J. Olson Reichhardt

Protein phosphorylation cycles are important mechanisms of the post translational modification of a protein and as such an integral part of intracellular signaling and control. We consider the sequential phosphorylation and…

分子网络 · 定量生物学 2019-11-06 Carsten Conradi , Elisenda Feliu , Maya Mincheva

We analyze a class of cell-bulk coupled PDE-ODE models, motivated by quorum and diffusion sensing phenomena in microbial systems, that characterize communication between localized spatially segregated dynamically active signaling…

斑图形成与孤子 · 物理学 2020-07-20 Sarafa A. Iyaniwura , Michael J. Ward

Eukaryotic cells possess a sensible chemical compass allowing them to orient toward sources of soluble chemicals. The extracellular chemical signal triggers separation of the cell membrane into two domains populated by different…

统计力学 · 物理学 2009-11-13 A. Gamba , I. Kolokolov , V. Lebedev , G. Ortenzi

The contact process is a stochastic process which exhibits a continuous, absorbing-state phase transition in the Directed Percolation (DP) universality class. In this work, we consider a contact process with a bias in conjunction with an…

统计力学 · 物理学 2013-05-20 A. Costa , R. A. Blythe , M. R. Evans

Understanding the (de)mixing behavior of multicomponent lipid bilayers is an important step towards unraveling the nature of spatial composition heterogeneities in cellular membranes and their role in biological function. We use…

软凝聚态物质 · 物理学 2018-05-17 Shushan He , Lutz Maibaum

We present a systematic theory of chemically active emulsions in the hydrodynamic limit by constructing a thermodynamically consistent framework in which the equilibrium is broken by chemo-stating of fuel molecules. For ternary solutions…

软凝聚态物质 · 物理学 2026-04-21 Efe Ilker , Kathrin Laxhuber , Jean-Francois Joanny , Frank Jülicher

Dynamic facilitation theory assumes short-ranged dynamic constraints to be the essential feature of supercooled liquids and draws much of its conclusions from the study of kinetically constrained models. While deceptively simple, these…

材料科学 · 物理学 2012-06-12 Thomas Speck , David Chandler

Near equilibrium, the symmetric part of the time-integrated steady-state covariance, i.e., the time integral of correlation functions, is governed by the fluctuation-dissipation theorem, while the antisymmetric part vanishes due to Onsager…

统计力学 · 物理学 2026-03-10 Timur Aslyamov , Massimiliano Esposito

Starting from a general classical model of many interacting particles we present a well defined step by step procedure to derive the continuum-mechanics equations of nonlinear elasticity theory with fluctuations which describe the…

统计力学 · 物理学 2022-06-02 Rudolf Haussmann

Boundary time crystals (BTC's) are non-equilibrium phases of matter occurring in quantum systems in contact to an environment, for which a macroscopic fraction of the many body system breaks time translation symmetry. We study BTC's in…

统计力学 · 物理学 2021-05-24 Luis Fernando dos Prazeres , Leonardo da Silva Souza , Fernando Iemini