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Estimating the required dose in radiotherapy is of crucial importance since the administrated dose should be sufficient to eradicate the tumor and at the same time should inflict minimal damage on normal cells. The probability that a given…

定量方法 · 定量生物学 2013-12-31 Andrew Dhawan , Kamran Kaveh , Mohammad Kohandel , Siv Sivaloganathan

Due to its precision and limited side effects, the particle therapy of cancer is gaining popularity. The number of patients treated with protons and light ions reached 150,000 worldwide. There are currently more than 80 facilities, which…

加速器物理 · 物理学 2020-10-01 Mariusz Sapinski

A novel radio guided surgery (RGS) technique for cerebral tumors using $\beta^{-}$ radiation is being developed. Checking the availability of a radio-tracer that can deliver a $\beta^{-}$ emitter to the tumor is a fundamental step in the…

Nuclear physics offers us a powerful tool: using nuclear resonance absorption lines to infer the physical conditions in astrophysical settings which are otherwise difficult to deduce. Present-day technology provides an increase in…

天体物理仪器与方法 · 物理学 2009-02-23 J. Greiner , S. E. Boggs , G. DiCocco , K. T. Freese , N. Gehrels , D. H. Hartmann , A. Iyudin , G. Kanbach , A. A. Zdziarski

Radiation damage effects represent one of the limits for technologies to be used in harsh radiation environments as space, radiotherapy treatment, high-energy phisics colliders. Different technologies have known tolerances to different…

仪器与探测器 · 物理学 2023-07-19 S. Fiore

Purpose: A radio-guided surgery technique with beta- -emitting radio-tracers was suggested to overcome the effect of the large penetration of gamma radiation. The feasibility studies in the case of brain tumors and abdominal neuro-endocrine…

A network of nanomachines (NMs) can be used to build a target detection system for a variety of promising applications. They have the potential to detect toxic chemicals, infectious bacteria, and biomarkers of dangerous diseases such as…

信息论 · 计算机科学 2024-01-10 Nithin V. Sabu , Abhishek K. Gupta

Dismantling nuclear power plants entails the production of a large amount of contaminated (or potentially contaminated) material whose disposal is of crucial importance. Most of the end products have to be stored in special repositories but…

数据分析、统计与概率 · 物理学 2021-07-07 Michele Pastena , Bastian Weinhorst , Günter Kanisch , Edgar Perez Lezama , Johannes Ratdke , Tim Thomas

Radiotherapy is an integral part of treatment for many patients with breast cancer. However, side effects can occur, Example fibrosis or erythema. If patients at higher risks of radiation induced side effects could be identified before…

医学物理 · 物理学 2024-09-04 Deborah E. M. Akuoko , Eliana Vasquez Osorio , Marcel Van Herk , Marianne Aznar

The air dose rate in an environment contaminated with 134Cs and 137Cs depends on the amount, depth profile and horizontal distribution of these contaminants within the ground. This paper introduces and verifies a tool that models these…

Radio-isotopes produced via proton induced reaction holds special significance regarding nuclear medicine, astrophysical p-process, theragnostic and diagnostic processes. $^{76}$Br, $^{80m}$Br and $^{61}$Cu are positron emitter and they are…

核理论 · 物理学 2022-07-20 Sourav Mondal , A. Gandhi , Rebecca Pachuau

Radiotherapy with heavy ions, in particular, 12C beams, is one of the most advanced forms of cancer treatment. Sharp dose gradients and high biological effectiveness in the target region make them an ideal tool to treat deep-seated and…

The background induced by the high penetration power of the gamma radiation is the main limiting factor of the current Radio-guided surgery (RGS). To partially mitigate it, a RGS with beta+ emitting radio-tracers has been suggested in…

While the use of combination therapy is increasing in prevalence for cancer treatment, it is often difficult to predict the exact interactions between different treatment forms, and their synergistic/antagonistic effects on patient health…

最优化与控制 · 数学 2021-01-29 Jayanth Pratap

In this study the technical risk analysis that was conducted using fault trees.With respect to the scenarios in Bangladesh, there is still no concrete proposal about a permanent disposal method, so this analysis is based on the propositions…

物理与社会 · 物理学 2018-10-09 Sabikun Nahar Sadia , Md. Iqbal Hosan , Md. Jafor Dewan , Saikat Ahmed

Nuclear radiation, which refers to the energy emitted from atomic nuclei during decay, poses significant risks to human health and environmental safety. Recently, advancements in monitoring technology have facilitated the effective…

机器学习 · 计算机科学 2025-05-29 Tengfei Lyu , Jindong Han , Hao Liu

We present measurements of radioactive contamination in the high-resistivity silicon charge-coupled devices (CCDs) used by the DAMIC experiment to search for dark matter particles. Novel analysis methods, which exploit the unique spatial…

We employ a multi-scale mechanistic approach to investigate radiation induced cell toxicities and deactivation mechanisms as a function of linear energy transfer in hadron therapy. Our theoretical model consists of a system of Markov chains…

医学物理 · 物理学 2019-05-01 Ramin Abolfath , Yusuf Helo , Lawrence Bronk , Alejandro Carabe , David Grosshans , Radhe Mohan

The radiotherapy of malignant diseases has reached much progress during the past decade. Thus, intensity modulated radiation therapy (IMRT) and VMAT (Rapidarc) now belong to the standard modalities of tumor treatment with high energy…

医学物理 · 物理学 2016-11-15 W. Ulmer , A. Carabe-Fernandez

Laser acceleration promises innovation in particle beam therapy of cancer where an ultra-compact accelerator system for cancer beam therapy can become affordable to a broad range of patients. This is not feasible without the introduction of…