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The continued integration of technology into all aspects of society stresses the need to identify and understand the risk associated with assimilating new technologies. This necessity is heightened when technology is used for medical…

密码学与安全 · 计算机科学 2017-09-18 Patrick Luckett , J Todd McDonald , William Bradley Glisson

Realistic nuclear reaction cross-section models are an essential ingredient of reliable heavy-ion transport codes. Such codes are used for risk evaluation of manned space exploration missions as well as for ion-beam therapy dose…

核理论 · 物理学 2021-10-27 F Luoni , F Horst , CA Reidel , A Quarz , L Bagnale , L Sihver , U Weber , RB Norman , W de Wet , M Giraudo , G Santin , J Norbury , M Durante

The linear-quadratic (LQ) model to describe the survival of irradiated cells may be the most frequently used biomathematical model in radiotherapy. There has been an intense debate on the mechanistic origin of the LQ model. An interesting…

医学物理 · 物理学 2021-05-31 Sara Neira , Araceli Gago-Arias , Jacobo Guiu-Souto , Juan Pardo-Montero

The only military application in which depleted-uranium (DU) alloys out-perform present-day tungsten alloys is long-rod penetration into a main battle-tank's armor. However, this advantage is only on the order of 10%, and it disappears when…

物理与社会 · 物理学 2007-05-23 Andre Gsponer

Soon after launch, the Advanced CCD Imaging Spectrometer (ACIS), one of the focal plane instruments on the Chandra X-ray Observatory, suffered radiation damage from exposure to soft protons during passages through the Earth's radiation…

天体物理学 · 物理学 2009-11-11 C. E. Grant , M. W. Bautz , S. M. Kissel , B. LaMarr , G. Y. Prigozhin

Beams of radioactive heavy ions allow researchers to study rare and unstable atomic nuclei, shedding light into the internal structure of exotic nuclei and on how chemical elements are formed in stars. However, the extraction and transport…

加速器物理 · 物理学 2025-06-25 Sergio Lopez-Caceres , Daniel Santiago-Gonzalez

Grade II gliomas are slowly growing primary brain tumors that affect mostly young patients and become fatal after a few years. Current clinical handling includes surgery as first line treatment. Cytotoxic therapies (radiotherapy RT or…

定量方法 · 定量生物学 2014-07-09 Victor M. Perez-Garcia

We propose a mathematical model for estimating biological damage caused by low-dose irradiation. We understand that the Linear Non Threshold (LNT) hypothesis is realized only in the case of no recovery effects. In order to treat the…

生物物理 · 物理学 2012-10-08 Yuichiro Manabe , Kento Ichikawa , Masako Bando

It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with…

等离子体物理 · 物理学 2014-05-13 K. W. D. Ledingham , P. R. Bolton , N. Shikazono , C-M. Ma

The goal of radiation therapy for cancer is to deliver prescribed radiation dose to the tumor while minimizing dose to the surrounding healthy tissues. To evaluate treatment plans, the dose distribution to healthy organs is commonly…

统计方法学 · 统计学 2024-05-24 Thai-Son Tang , Zhihui Liu , Ali Hosni , John Kim , Olli Saarela

Geant4 software is used to study 10 MeV photon beams and 100 MeV proton beams. Conclusions are drawn as to the advantages and disadvantages of each therapy, with some additional commentary on the secondary effects of radiation damage in…

医学物理 · 物理学 2020-06-24 Austin A. Morris

Carbon-ion radiotherapy provides high dose conformity for lung cancer, but its benefit is limited by two sources of uncertainties: interplay between scanned beam delivery and tumor motion, and dose modulation from heterogeneous lung tissue.…

医学物理 · 物理学 2026-02-18 Maria Chiara Martire , Lennart Volz , Marco Durante , Christian Graeff

We calculate the relative abundance of the radioactive isotopes Iodine-131 and Cesium-137 produced by nuclear fission in reactors and compare it with data taken at the troubled Fukushima Dai-ichi nuclear power plant. The ratio of…

核理论 · 物理学 2012-01-03 T. Matsui

Teleoperated robots are playing an increasingly important role in military actions and medical services. In the future, remotely operated surgical robots will likely be used in more scenarios such as battlefields and emergency response. But…

机器人学 · 计算机科学 2015-05-13 Tamara Bonaci , Jeffrey Herron , Tariq Yusuf , Junjie Yan , Tadayoshi Kohno , Howard Jay Chizeck

The radiological doses and hazard indices of natural radionuclides $^{238}$U,$^{232}$Th and $^{40} $K in soil samples from Kerbala city were evaluated using gamma-ray spectroscopy system using NaI(Tl) ${"1.5\times 2"}$ detector in…

仪器与探测器 · 物理学 2015-12-01 Mohammed Abdulhussain Al-Kaabi , Ahmed Al-Shimary

As technology advances towards more connected and digital environments, medical devices are becoming increasingly connected to hospital networks and to the Internet, which exposes them, and thus the patients using them, to new cybersecurity…

密码学与安全 · 计算机科学 2020-02-18 Tom Mahler , Yuval Elovici , Yuval Shahar

In this paper we consider an optimal control problem arising from a chemotherapeutic drug treatment for tumor cells in a living tissue. The mathematical model for the interaction of chemotherapeutic drug and the normal, tumor and immune…

偏微分方程分析 · 数学 2022-12-13 Hong-Ming Yin

We investigate the possibility of usage of the parametric X-ray radiation (PXR) for the selective therapy of superficial sulfur-containing tumor tissues. In these tissues, the concentration of sulfur atoms is significantly higher than in…

生物物理 · 物理学 2025-10-07 N. Q. San , O. D. Skoromnik , A. U. Leonau , V. Q. Nha , I. D. Feranchuk

Photon-induced nuclear excitation (i.e. photo-excitation) can be used for production of nuclear isomers, which have potential applications in astrophysics, energy storing, and medical diagnosis and treatment. This paper presents a…

核实验 · 物理学 2020-12-18 Wan-ting Pan , Hao-yang Lan , Zhi-guo Ma , Zhi-chao Zhu , Wen Luo

In radiation therapy tumor size, and thus also volume, has a significant impact on the local control of tumors. Moreover, tumor volume is a significant prognostic factor for modelling and predicting therapeutic outcomes in cancer treatment.…

医学物理 · 物理学 2023-03-21 Stephan Radonic , Jürgen Besserer , Jessica Kneubühl , Valeria Meier , Uwe Schneider
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