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We describe a visual computing approach to radiation therapy (RT) planning, based on spatial similarity within a patient cohort. In radiotherapy for head and neck cancer treatment, dosage to organs at risk surrounding a tumor is a large…

A first comprehensive study is presented on radioactivity concentrations and dose rates in 87 commonly used materials, manufactured or imported in Cyprus, for building purposes. The natural radioactivity of K-40, Th-232, U-238 and Ra-226 is…

医学物理 · 物理学 2011-02-23 F. Michael , H. Tsertos , Y. Parpottas

Oncolytic virotherapy is an experimental cancer treatment that uses genetically engineered viruses to target and kill cancer cells. One major limitation of this treatment is that virus particles are rapidly cleared by the immune system,…

细胞行为 · 定量生物学 2019-12-02 Adrianne L. Jenner , Chae-Ok Yun , Peter S. Kim , Adelle C. F. Coster

We develop a multiphysics-based model to predict the response of localized tumors to combined-hyperthermia-radiotherapy (CHR) treatment. This procedure combines hyperthermia (tumor heating) with standard radiotherapy to improve efficacy of…

组织与器官 · 定量生物学 2019-07-05 Japan K. Patel , Richard Vasques , Barry D. Ganapol

The paper presents many facets of medical imaging investigations radiological risks. The total volume of prescribed medical investigations proves a serious lack in monitoring and tracking of the cumulative radiation doses in many health…

医学物理 · 物理学 2015-11-09 Lidia Dobrescu , Gheorghe-Cristian Rădulescu

A fundamental model of tumor growth in the presence of cytotoxic chemotherapeutic agents is formulated. The model allows to study the role of the Norton-Simon hypothesis in the context of dose-dense chemotherapy. Dose-dense protocols aim at…

Distant metastases (DM) refer to the dissemination of tumors, usually, beyond the organ where the tumor originated. They are the leading cause of death in patients with soft-tissue sarcomas (STSs). Positron emission tomography-computed…

图像与视频处理 · 电气工程与系统科学 2021-12-22 Yige Peng , Lei Bi , Ashnil Kumar , Michael Fulham , Dagan Feng , Jinman Kim

The highly energetic electrons in a transmission electron microscope (TEM) can alter or even completely destroy the structure of samples before sufficient information can be obtained. This is especially problematic in the case of zeolites,…

材料科学 · 物理学 2021-05-05 Abner Velazco , Daen Jannis , Armand Béché , Johan Verbeeck

Mapping radioactive contamination using aerial survey measurements is an area under active investigation today. The radiometric aerial survey technique has been extensively applied following reactor accidents and also would provide a key…

数据分析、统计与概率 · 物理学 2020-01-13 Laurel E. Sinclair , Richard Fortin

Charged Particle Therapy is a technique for cancer treatment that exploits hadron beams, mostly protons and carbons. A critical issue is the monitoring of the dose released by the beam to the tumor and to the surrounding tissues. We present…

Radioactive decay of unstable atomic nuclei leads to liberation of nuclear binding energy in the forms of gamma-ray photons and secondary particles (electrons, positrons); their energy then energises surrounding matter. Unstable nuclei are…

高能天体物理现象 · 物理学 2023-04-05 Roland Diehl

In the 21st century, new and alternative non-radioactive methods for cancer treatment have been developed. One of this is magnetic hyperthermia (MH), which is based on the ability of magnetic nanoparticles (MNP) to transduce electromagnetic…

医学物理 · 物理学 2020-07-28 Christian Calvache , Jenny Mera-Córdoba , Diego F. Coral

Low grade gliomas (LGGs) are a group of primary brain tumors usually encountered in young patient populations. These tumors represent a difficult challenge because many patients survive a decade or more and may be at a higher risk for…

Despite all the advances achieved in the field of tumor-biology research, in most cases conventional therapies including chemotherapy are still the leading choices. The main disadvantage of these treatments, in addition to the low…

Purpose of review: Artificial intelligence (AI) has become popular in medical applications, specifically as a clinical support tool for computer-aided diagnosis. These tools are typically employed on medical data (i.e., image, molecular…

机器学习 · 计算机科学 2022-06-08 Ahmad Chaddad , Yousef Katib , Lama Hassan

Sparse static detector networks in urban environments can be used in efforts to detect illicit radioactive sources, such as stolen nuclear material or radioactive "dirty bombs". We use detailed simulations to evaluate multiple…

仪器与探测器 · 物理学 2025-02-13 E. Rofors , N. Abgrall , M. S. Bandstra , R. J. Cooper , D. Hellfeld , T. H. Y. Joshi , V. Negut , B. J. Quiter , M. Salathe

In carbon-therapy, the interaction of the incoming beam with human tissues may lead to the production of a large amount of nuclear fragments and secondary light particles. An accurate estimation of the biological dose deposited into the…

核实验 · 物理学 2014-06-02 J. Dudouet , D. Cussol , D. Durand , M. Labalme

Delineating and planning with respect to regions suspected to contain microscopic tumor cells is an inherently uncertain task in radiotherapy. The recently proposed \textit{clinical target distribution} (CTD) is an alternative to the…

医学物理 · 物理学 2023-04-26 Ivar Bengtsson , Anders Forsgren , Albin Fredriksson

Around half of all cancer patients, world-wide, will receive some form of radiotherapy (RT) as part of their treatment. And yet, despite the rapid advance of high-throughput screening to identify successful chemotherapy drug candidates,…

医学物理 · 物理学 2023-04-07 Wojciech Ozimek , Rafał Banaś , Paweł Gora , Simon D. Angus , Monika J. Piotrowska

Stereotactic body radiation therapy (SBRT) refers to focusing high-energy rays in three-dimensional space on the tumor lesion area, reducing the dose received by surrounding normal tissues, which can effectively improve the local control…

医学物理 · 物理学 2024-02-27 Yanqi Zong , Zhengrong Cui , Luqi Lin , Sihao Wang , Yizhi Chen