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In many applications of survival data analysis, the individuals are treated in different medical centres or belong to different clusters defined by geographical or administrative regions. The analysis of such data requires accounting for…

统计方法学 · 统计学 2022-05-03 Rubio , F. J. , Drikvandi , R

Deep-learning techniques, particularly the transformer model, have shown great potential in enhancing the prediction performance of longitudinal health records. While previous methods have mainly focused on fixed-time risk prediction,…

机器学习 · 计算机科学 2024-05-03 Moshe Zisser , Dvir Aran

This article analyzes the problem of estimating the time until an event occurs, also known as survival modeling. We observe through substantial experiments on large real-world datasets and use-cases that populations are largely…

机器学习 · 计算机科学 2019-05-13 David Hubbard , Benoit Rostykus , Yves Raimond , Tony Jebara

Tree methods (recursive partitioning) are a popular class of nonparametric methods for analyzing data. One extension of the basic tree methodology is the survival tree, which applies recursive partitioning to censored survival data. There…

统计方法学 · 统计学 2017-03-01 Wei Fu , Jeffrey S. Simonoff

Lung cancer is a major cause of cancer-related deaths, and early diagnosis and treatment are crucial for improving patients' survival outcomes. In this paper, we propose to employ convolutional neural networks to model the non-linear…

图像与视频处理 · 电气工程与系统科学 2024-08-20 Xiawei Wang , James Sharpnack , Thomas C. M. Lee

Background: Accurate survival time estimates aid end-of-life medical decision-making. Objectives: Develop an interpretable survival model for elderly residential aged care residents using advanced machine learning. Setting: A major…

机器学习 · 计算机科学 2023-12-11 Teo Susnjak , Elise Griffin

The tumor microenvironment (TME) has emerged as a promising source of prognostic biomarkers. To fully leverage its potential, analysis methods must capture complex interactions between different cell types. We propose HiGINE -- a…

计算机视觉与模式识别 · 计算机科学 2025-12-10 Olle Edgren Schüllerqvist , Jens Baumann , Joakim Lindblad , Love Nordling , Artur Mezheyeuski , Patrick Micke , Nataša Sladoje

Colorectal liver metastases (CLM) significantly impact colon cancer patients, influencing survival based on systemic chemotherapy response. Traditional methods like tumor grading scores (e.g., tumor regression grade - TRG) for prognosis…

The reproduction number of deterministic models is an essential quantity to predict whether an epidemic will spread or die out. Thresholds for disease extinction contribute crucial knowledge on disease control, elimination, and mitigation…

种群与进化 · 定量生物学 2013-08-08 Ling Xue , Caterina Scoglio

Accurate survival prediction is crucial for development of precision cancer medicine, creating the need for new sources of prognostic information. Recently, there has been significant interest in exploiting routinely collected clinical and…

机器学习 · 计算机科学 2021-03-23 Sejin Kim , Michal Kazmierski , Benjamin Haibe-Kains

The existing life table method needs to calculate the age-specific mortality first, not only has too many and complicated calculation steps, but also introduces the multiple approximation to bring error. This paper redefines the probability…

其他定量生物学 · 定量生物学 2020-04-21 Weidong Huang

When oncologists estimate cancer patient survival, they rely on multimodal data. Even though some multimodal deep learning methods have been proposed in the literature, the majority rely on having two or more independent networks that share…

图像与视频处理 · 电气工程与系统科学 2022-09-13 Numan Saeed , Ikboljon Sobirov , Roba Al Majzoub , Mohammad Yaqub

Patient monitoring is vital in all stages of care. We here report the development and validation of ICU length of stay and mortality prediction models. The models will be used in an intelligent ICU patient monitoring module of an…

机器学习 · 计算机科学 2021-05-11 Khalid Alghatani , Nariman Ammar , Abdelmounaam Rezgui , Arash Shaban-Nejad

Decision trees and random forest remain highly competitive for classification on medium-sized, standard datasets due to their robustness, minimal preprocessing requirements, and interpretability. However, a single tree suffers from high…

机器学习 · 统计学 2025-12-02 Cencheng Shen , Yuexiao Dong , Carey E. Priebe

Epidemiologic studies and clinical trials with a survival outcome are often challenged by immortal time (IMT), a period of follow-up during which the survival outcome cannot occur because of the observed later treatment initiation. It has…

应用统计 · 统计学 2022-02-08 Jiping Wang , Peter Peduzzi , Michael Wininger , Shuangge Ma

We propose a flexible joint longitudinal-survival framework to examine the association between longitudinally collected biomarkers and a time-to-event endpoint. More specifically, we use our method for analyzing the survival outcome of…

应用统计 · 统计学 2018-07-09 Sepehr Akhavan Masouleh , Tracy Holsclaw , Babak Shahbaba , Daniel L. Gillen

The rates of escape and reversion in response to selection pressure arising from the host immune system, notably the cytotoxic T-lymphocyte (CTL) response, are key factors determining the evolution of HIV. Existing methods for estimating…

种群与进化 · 定量生物学 2013-02-12 Duncan Palmer , John Frater , Rodney Philips , Angela McLean , Gil McVean

Accurate survival prediction in Non-Small Cell Lung Cancer (NSCLC) requires integrating clinical, radiological, and histopathological data. Multimodal Deep Learning (MDL) can improve precision prognosis, but small cohorts and missing…

We introduce random survival forests, a random forests method for the analysis of right-censored survival data. New survival splitting rules for growing survival trees are introduced, as is a new missing data algorithm for imputing missing…

应用统计 · 统计学 2008-11-12 Hemant Ishwaran , Udaya B. Kogalur , Eugene H. Blackstone , Michael S. Lauer

Longitudinal imaging studies are essential to understanding the neural development of neuropsychiatric disorders, substance use disorders, and the normal brain. The main objective of this paper is to develop a two-stage adjusted…

应用统计 · 统计学 2011-08-12 Xiaoyan Shi , Joseph G. Ibrahim , Jeffrey Lieberman , Martin Styner , Yimei Li , Hongtu Zhu