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Recently, there have been efforts towards understanding the sampling behaviour of event-triggered control (ETC), for obtaining metrics on its sampling performance and predicting its sampling patterns. Finite-state abstractions, capturing…

系统与控制 · 电气工程与系统科学 2022-06-09 Giannis Delimpaltadakis , Luca Laurenti , Manuel Mazo

Neuronal spiking exhibits an exquisite combination of modulation and robustness properties, rarely matched in artificial systems. We exploit the particular interconnection structure of conductance based models to investigate this remarkable…

神经元与认知 · 定量生物学 2013-11-12 Guillaume Drion , Alessio Franci , Vincent Seutin , Rodolphe Sepulchre

We consider a stochastic version of an excitable system based on the Morris-Lecar model of a neuron, in which the noise originates from stochastic Sodium and Potassium ion channels opening and closing. One can analyze neural excitability in…

神经元与认知 · 定量生物学 2015-06-15 Jay M. Newby , Paul C. Bressloff , James P. Keener

The voltage-conductance kinetic equation for integrate and fire neurons has been used in neurosciences since a decade and describes the probability density of neurons in a network. It is used when slow conductance receptors are activated…

偏微分方程分析 · 数学 2013-10-11 Benoit Perthame , Delphine Salort

Cortical neurons include many sub-cellular processes, operating at multiple timescales, which may affect their response to stimulation through non-linear and stochastic interaction with ion channels and ionic concentrations. Since new…

神经元与认知 · 定量生物学 2014-05-01 Daniel Soudry , Ron Meir

High-resolution tunneling electron spin transport properties (longitudinal spin current (LSC) and spin transfer torque (STT) maps) of topologically distinct real-space magnetic skyrmionic textures are reported by employing a 3D-WKB combined…

材料科学 · 物理学 2020-10-27 Krisztián Palotás , Levente Rózsa , Eszter Simon , László Szunyogh

Mammalian brain is a complex organ that contains billions of neurons. These neurons form various neural circuits that control the perception, cognition, emotion and behavior. Developing in vivo neuronal labeling and imaging techniques is…

神经元与认知 · 定量生物学 2022-11-15 Shana Li , Xiang Xu , Canjun Li , Ziyan Xu , Qiong Ye , Yan Zhang , Chunlei Cang , Jie Wen

We consider exploratory methods for the discovery of cortical functional connectivity. Typically, data for the i-th subject (i=1...NS) is represented as an NVxNT matrix Xi, corresponding to brain activity sampled at NT moments in time from…

统计方法学 · 统计学 2011-03-17 Roberto D. Pascual-Marqui , Rolando J. Biscay-Lirio

Synaptic integration is a prominent aspect of neuronal information processing. The detailed mechanisms that modulate synaptic inputs determine the computational properties of any given neuron. We study a simple model for the summation of…

神经元与认知 · 定量生物学 2021-07-15 Adrian Joseph Alva , Harjinder Singh

Probabilistic inference offers a principled framework for understanding both behaviour and cortical computation. However, two basic and ubiquitous properties of cortical responses seem difficult to reconcile with probabilistic inference:…

神经元与认知 · 定量生物学 2017-01-03 Laurence Aitchison , Máté Lengyel

With our ability to record more neurons simultaneously, making sense of these data is a challenge. Functional connectivity is one popular way to study the relationship between multiple neural signals. Correlation-based methods are a set of…

神经元与认知 · 定量生物学 2017-06-09 Tiger W. Lin , Anup Das , Giri P. Krishnan , Maxim Bazhenov , Terrence J. Sejnowski

Characterizing the brain dynamics during different cortical states can reveal valuable information about its patterns across various cognitive processes. In particular, studying the differences between awake and sleep stages can shed light…

This article presents a mini-review about the progress in inferring monosynaptic connections from spike trains of multiple neurons over the past twenty years. First, we explain a variety of meanings of ``neuronal connectivity'' in different…

神经元与认知 · 定量生物学 2024-03-19 Ryota Kobayashi , Shigeru Shinomoto

Humans and other animals behave as if we perform fast Bayesian inference underlying decisions and movement control given uncertain sense data. Here we show that a biophysically realistic model of the subthreshold membrane potential of a…

神经元与认知 · 定量生物学 2014-06-20 Michael G. Paulin , Andre van Schaik

Quantification of information content and its temporal variation in intracellular calcium spike trains in neurons helps one understand functions such as memory, learning, and cognition. Such quantification could also reveal pathological…

信号处理 · 电气工程与系统科学 2021-02-02 Sathish Ande , Srinivas Avasarala , Jayanth R Regatti , Neha Pandey , Sarpras Swain , Ajith Karunarathne , Lopamudra Giri , Soumya Jana

We consider a model of interacting neurons where the membrane potentials of the neurons are described by a multidimensional piecewise deterministic Markov process (PDMP) with values in ${\mathbb R}^N, $ where $ N$ is the number of neurons…

统计理论 · 数学 2016-10-04 Pierre Hodara , Nathalie Krell , Eva Löcherbach

One of the central problems in neuroscience is reconstructing synaptic connectivity in neural circuits. Synapses onto a neuron can be probed by sequentially stimulating potentially pre-synaptic neurons while monitoring the membrane voltage…

神经元与认知 · 定量生物学 2012-10-05 Tao Hu , Dmitri B. Chklovskii

Functional magnetic resonance imaging (fMRI) enables indirect detection of brain activity changes via the blood-oxygen-level-dependent (BOLD) signal. Conventional analysis methods mainly rely on the real-valued magnitude of these signals.…

统计方法学 · 统计学 2023-10-31 Zhengxin Wang , Daniel B. Rowe , Xinyi Li , D. Andrew Brown

We have used the method of generating functional in imaginary time to derive the current-voltage characteristics of a tunnel junction with arbitrary tunneling conductance, connected in series with an external impedance and a voltage source.…

介观与纳米尺度物理 · 物理学 2009-10-31 X. H. Wang , K. A. Chao

Brain function results from communication between neurons connected by complex synaptic networks. Synapses are themselves highly complex and diverse signaling machines, containing protein products of hundreds of different genes, some in…