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We consider voltage-driving DNA translocation through a nanopore in the present study. By assuming the DNA is coaxial with the cylindrical nanopore, a hydrodynamic model for determining effective force on a single DNA molecule in a nanopore…

软凝聚态物质 · 物理学 2013-06-19 Wen-Yue Tang , Guo-Hui Hu

Measurements of electron transfer rates as well as of charge transport characteristics in DNA produced a number of seemingly contradictory results, ranging from insulating behaviour to the suggestion that DNA is an efficient medium for…

软凝聚态物质 · 物理学 2007-05-23 R. Bulla , R. Gutierrez , G. Cuniberti

Electronic properties of DNA are believed to play a crucial role in many phenomena in living organisms, for example the location of DNA lesions by base excision repair (BER) glycosylases and the regulation of tumor-suppressor genes such as…

其他定量生物学 · 定量生物学 2012-02-21 Chi-Tin Shih , Stephen A. Wells , Ching-Ling Hsu , Yun-Yin Cheng , Rudolf A. Römer

Modeling charge transport in DNA is essential to understand and control the electrical properties and develop DNA-based nanoelectronics. DNA is a fluctuating molecule that exists in a solvent environment, which makes the electron…

生物物理 · 物理学 2023-10-05 Hashem Mohammad , M. P. Anantram

The high linear charge density of 20-base-pair oligomers of DNA is shown to lead to a striking non-monotonic dependence of the long-time self-diffusion on the concentration of the DNA in low-salt conditions. This generic non-monotonic…

软凝聚态物质 · 物理学 2009-11-13 M. G. McPhie , G. Naegele

We develop an analytical theory that accounts for the image and surface charge interactions between a charged dielectric membrane and a DNA molecule translocating through the membrane. Translocation events through neutral carbon-based…

软凝聚态物质 · 物理学 2016-08-03 Sahin Buyukdagli , T. Ala-Nissila

In this paper we consider dipole-mediated correlations between DNA and enzymes in the context of their water environment. Such correlations emerge from electric dipole-dipole interactions between aromatic ring structures in DNA and in…

生物物理 · 物理学 2017-02-06 P. Kurian , A. Capolupo , T. J. A. Craddock , G. Vitiello

The rapid progress in the field of molecular electronics has led to an increasing interest on DNA oligomers as possible components of electronic circuits at the nanoscale. For this, however, an understanding of charge transfer and transport…

软凝聚态物质 · 物理学 2007-05-23 R. Gutierrez , G. Cuniberti

The control over DNA elongation in nanofluidic devices holds great potential for large-scale genomic analysis. So far, the manipulation of DNA in nanochannels has been mostly carried out with electrophoresis and seldom with hydrodynamics,…

The fluidic behavior of water at the micro/nano scale is studied by using of single DNA molecules as a model system. Stable curved DNA patterns with spans about one micron were generated by using of water flows, and observed by Atomic Force…

生物物理 · 物理学 2007-05-23 Yi Zhang , Huabing Li , Xiaoling Lei , Junhong Lv , Xiaobai Ai , Hu Jun , Shiyi Chen , Fang Haiping

Due to its polyionic character the DNA double helix is stable and biologically active only in salty aqueous media where its charge is compensated by solvent counterions. Monovalent metal ions are ubiquitous in DNA environment and they are…

生物物理 · 物理学 2007-05-23 Alexey K. Mazur

We have investigated the conduction over a wide range of temperature of $\lambda$ DNA molecules deposited across slits etched through a few nanometers thick platinum film. The slits are insulating before DNA deposition but contain metallic…

介观与纳米尺度物理 · 物理学 2015-05-20 A. D. Chepelianskii , D. Klinov , A. Kasumov , S. Guéron , O. Pietrement , S. Lyonnais , H. Bouchiat

The dielectrophoresis method for trapping and attaching nanoscale double-stranded DNA between nanoelectrodes was developed. The method gives a high yield of trapping single or a few molecules only which enables transport measurements at the…

软凝聚态物质 · 物理学 2007-05-23 S. Tuukkanen , A. Kuzyk , J. J. Toppari , V. P. Hytonen , T. Ihalainen , P. Torma

The structure of DNA Binding Proteins enables a strong interaction with their specific target site on DNA. However, recent single molecule experiment reported that proteins can diffuse on DNA. This suggests that the interactions between…

生物大分子 · 定量生物学 2015-05-13 Vincent Dahirel , Fabien Paillusson , Marie Jardat , Maria Barbi , Jean-Marc Victor

We investigate the impact of dielectric boundary forces on the translocation process of charged rigid DNA segments through solid neutral nanopores. We assess the electrostatic contribution to the translocation free energy barrier of a model…

软凝聚态物质 · 物理学 2010-02-16 Stefan Kesselheim , Marcello Sega , Christian Holm

Positions of protons in DNA hydrogen bonds are fundamental for the fidelity of the replication process. Because the hydrogen bond is partially covalent the electronic structure of DNA plays an important role in the replication process.…

强关联电子 · 物理学 2007-05-23 Chun-Min Chang , A. H. Castro Neto , A. R. Bishop

Dynamic structuring of water is a key player in a large class of processes underlying biochemical and technological developments today, the latter often involving electric fields. However, the anisotropic coupling between the water…

软凝聚态物质 · 物理学 2019-05-29 Andreas Baer , Zoran Miličević , David M. Smith , Ana-Sunčana Smith

Flow-driven rotary motors drive functional processes in human society such as windmills and water wheels. Although examples of such rotary motors also feature prominently in cell biology, their synthetic construction at the nanoscale has…

The chirality-induced spin selectivity (CISS), demonstrated in diverse chiral molecules by numerous experimental and theoretical groups, has been attracting extensive and ongoing interest in recent years. As the secondary structure of DNA,…

介观与纳米尺度物理 · 物理学 2020-11-11 Pei-Jia Hu , Si-Xian Wang , Xiao-Hui Gao , Yan-Yang Zhang , Tie-Feng Fang , Ai-Min Guo , Qing-Feng Sun

In the field of DNA nanotechnology, it is common wisdom that charge transport occurs through the {\pi} stacked bases of double-stranded DNA. However, recent experimental findings by Zhuravel et. al. [Nat. Nanotech. 15, 836 (2020)] suggest…

介观与纳米尺度物理 · 物理学 2024-12-31 Sourav Kundu , Siddhartha Lal