种群与进化
The process of speciation, where an ancestral species divides in two or more new species, involves several geographic, environmental and genetic components that interact in a complex way. Understanding all these elements at once is…
Scientific studies in many areas of biology routinely employ evolutionary analyses based on the probabilistic inference of phylogenetic trees from molecular sequence data. Evolutionary processes that act at the molecular level are highly…
A deterministic nonlinear ordinary differential equation model for mosquito dynamics in which the mosquitoes can quest for blood either within a human population or within non-human/vertebrate populations is derived and studied. The model…
Changing temperature, precipitation regimes, and sea level rise, often associated with climate change, cause salinity intrusion into groundwater and surface water, affecting aquatic ecosystems. This study investigates the impacts of…
Zoonotic disease transmission between animals and humans is a growing risk and the agricultural context acts as a likely point of transition, with individual heterogeneity acting as an important contributor. Thus, understanding the dynamics…
The evolutionary relationships between species are typically represented in the biological literature by rooted phylogenetic trees. However, a tree fails to capture ancestral reticulate processes, such as the formation of hybrid species or…
The emergence or adaptation of pathogens may lead to epidemics, highlighting the need for a thorough understanding of pathogen evolution. The tradeoff hypothesis suggests that virulence evolves to reach an optimal transmission intensity…
Chromosomal rearrangements, particularly those mediated by transposable elements (TEs), can drive adaptive evolution by creating chimeric genes, inducing de novo gene formation, or altering gene expression. Here, we investigate…
In recent years, biodiversity measures have gained prominence as essential tools for ecological and environmental assessments, particularly in the context of increasingly complex and large-scale datasets. We provide a comprehensive review…
We study an almost periodic version of a metapopulation model developed by Tilman \textit{et.al} and Nee \textit{et.al} in the nineties, which generalizes the classical Levins approach by considering several species in competition affected…
The ecosystem considered in this study is the outcome of a lengthy sequence of historical and ecological events. Patagonia's indigenous fauna comprises survivors of five significant extinction events, with the notable presence of the puma…
The bacterium Xylella fastidiosa (Xf) is mainly transmitted by the spittlebug, Philaenus spumarius, in Europe, where it has caused significant economic damage to olive and almond trees. Understanding the factors that determine disease…
This book brings new mathematical rigour to the ongoing vigorous debate on how to quantify biological diversity. The question "what is diversity?" has surprising mathematical depth, and breadth too: this book involves parts of mathematics…
Chromosomal inversions are structural mutations resulting in the reversal of the gene order along the corresponding genomic region. Due to their influence on recombination patterns, they can have a major influence on genetic variation and…
Wolbachia is a naturally occurring bacterium that can infect Aedes mosquitoes and reduce the transmission of mosquito-borne diseases, including dengue fever, Zika, and chikungunya. Field trials have been conducted worldwide to suppress…
The importation and subsequent establishment of novel pathogenic strains in a population is subject to a large degree of uncertainty due to the stochastic nature of the disease dynamics. Mathematical models need to take this stochasticity…
We used a spatially explicit agent-based model of SARS-CoV-2 transmission combined with spatially fine-grained COVID-19 observation data from Public Health Scotland to investigate the initial rise of the Omicron (BA.1) variant of concern.…
The seasonal human influenza virus undergoes rapid evolution, leading to significant changes in circulating viral strains from year to year. These changes are typically driven by adaptive mutations, particularly in the antigenic epitopes,…
Cancer is most commonly viewed as resulting from somatic mutations enhancing proliferation and invasion. Some hypotheses further propose that these new capacities reveal a breakdown of multicellularity allowing cancer cells to escape…
Despite having triggered devastating pandemics in the past, our ability to quantitatively assess the emergence potential of individual strains of animal influenza viruses remains limited. This study introduces Emergenet, a tool to infer a…