种群与进化
Modeling fish growth is an important research topic in ecological and fishery sciences because body weight statistics directly affect the total biomass of fish in a habitat, which in turn affects their population dynamics. Many models of…
We derive a single-cell level understanding of metabolism in an isogenic cyanobacterial population by integrating secondary ion mass spectrometry (SIMS) derived multi-isotope uptake measurements of Synechocystis sp. PCC6803 with a…
Understanding the relationship between a populations probability of extinction and its carrying capacity frames conservation status assessments and guides efforts to understand and mitigate the ongoing biodiversity crisis. Despite this, our…
Metapopulation models are commonly used in ecology, evolution, and epidemiology. These models usually entail homogeneity assumptions within patches and study networks of migration between patches to generate insights into conservation of…
We construct and analyze structured replicator dynamics of the Snowdrift game. In our model, the offspring is put in juvenile compartments and then mature and join adult compartments with strategy-dependent rates. This is augmented by death…
Antibiotic resistance (AR) is one of the greatest public health challenges worldwide. Processes that allow the reduction of AR predictor of hospital wastewater has become crucial process that contributes to the protection of public health…
Populations can become spatially organised through chemotaxis autoattraction, wherein population members release their own chemoattractant. Standard models of this process usually assume phenotypic homogeneity, but recent studies have shed…
The storage effect is a general explanation for ecological coexistence, wherein different species specialize on different states of a fluctuating environment, e.g., hot vs. cold years. Despite the storage effect's prominence in theoretical…
Rapidly evolving viruses use antigenic drift as a key mechanism to evade host immunity and persist in real populations. While traditional models of antigenic drift and epidemic spread rely on low-dimensional antigenic spaces, genomic…
Evolutionary dynamics are shaped by a variety of fundamental, generic drivers, including spatial structure, ecology, and selection pressure. These drivers impact the trajectory of evolution, and have been hypothesized to influence…
Density dependence is important in the ecology and evolution of microbial and cancer cells. Typically, we can only measure net growth rates, but the underlying density-dependent mechanisms that give rise to the observed dynamics can…
Multiscale mathematical models of hepatitis C infection have been instrumental in our understanding of direct acting antivirals. These models include the mechanisms driving intracellular viral production and explicitly model the…
This article investigates stochastic epidemic models with partial information and addresses the estimation of current values of not directly observable states. The latter is also called nowcasting and related to the so-called "dark figure"…
Genomes contain the mutational footprint of an organism's evolutionary history, shaped by diverse forces including ecological factors, selective pressures, and life history traits. The sequentially Markovian coalescent (SMC) is a versatile…
From tumour invasion to cell sorting and animal territoriality, many biological systems rely on nonlocal interactions that drive complex spatial organisation. Partial differential equations (PDEs) with nonlocal advection are increasingly…
Evolvability is defined as the ability of a population to generate heritable variation to facilitate its adaptation to new environments or selection pressures. In this article, we consider evolvability as a phenotypic trait subject to…
HIV pre-exposure Prophylaxis (PrEP) has become essential for global HIV control, but its implementation coincides with rising bacterial STI rates among men who have sex with men (MSM). While risk-compensation behavioral changes like reduced…
Antimicrobial resistance is a threat to public health with millions of deaths linked to drug resistant infections every year. To mitigate resistance, common strategies that are used are combination therapies and therapy switching. However,…
We investigate sub-leading orders of the classic SEIR-model using contact matrices from modeling of the Omicron and Delta variants of COVID-19 in Denmark. The goal of this is to illustrate when the growth rate, and by extension the…
We examine the impact of the maintenance cost of social links on cooperative behavior in the Prisoner's Dilemma game on the Barab\'asi-Albert scale-free network with a pairwise stochastic imitation. We show by means of Monte Carlo…