种群与进化
Teachers hold a prominent place in modern societies, particularly where education is compulsory and widely institutionalized. This ubiquity obscures an underlying question: why do societies designate certain individuals exclusively for the…
This work investigates the benefits of implementing a systematic approach to social isolation policies during epidemics. We develop a mixed integer data-driven model predictive control (MPC) scheme based on an SIHRD model which is…
While cancer has traditionally been considered a genetic disease, mounting evidence indicates an important role for non-genetic (epigenetic) mechanisms. Common anti-cancer drugs have recently been observed to induce the adoption of…
The built environment provides an excellent setting for interdisciplinary research on the dynamics of microbial communities. The system is simplified compared to many natural settings, and to some extent the entire environment can be…
Investigations of infectious disease outbreaks often focus on identifying place- and context-dependent factors responsible for emergence and spread, resulting in phenomenological narratives ill-suited to developing generalizable predictive…
In the last decade, some algebraic tools have been successfully applied to phylogenetic reconstruction. These tools are mainly based on the knowledge of equations describing algebraic varieties associated to phylogenetic trees evolving…
In this paper, we study a stochastic susceptible-infected-susceptible (SIS) epidemic model that includes an additional immigration process. In the presence of multiplicative noise, generated by environmental perturbations, the model…
The universal genetic code presents a fundamental paradox in molecular biology. Recent advances in synthetic biology have demonstrated that the code is remarkably flexible--organisms can survive with 61 codons instead of 64, natural…
In this paper, we study the significance of ecological interactions and separation of birth and death dynamics in stochastic heterogeneous populations via general birth-death processes. Interactions can manifest through the birth dynamics,…
Sustainability has been defined as meeting the needs of the present without compromising the ability of future generations to meet their own needs. But what are the needs of the present? And are they met? From the poor performance of the…
Many biological systems regulate phenotypic heterogeneity as a fitness-maximising strategy in uncertain and dynamic environments. Analysis of such strategies is typically confined both to a discrete set of environmental conditions, and to a…
In the context of population dynamics, identifying effective model features, such as fecundity and mortality rates, is generally a complex and computationally intensive process, especially when the dynamics are heterogeneous across the…
1. Although environmental variability is expected to play a more prominent role under climate change, current demographic models that ignore the differential environmental histories of cohorts across generations are unlikely to accurately…
Researchers puzzle over questions as to how rare species survive extinction, and why a significant proportion of microbial taxa are dormant. Computational simulation modeling by a genetic algorithm provides some answers. First, a…
Ecological communities are composed of species interactions that respond to environmental fluctuations. Despite increasing evidence of temporal variation in these interactions, most theoretical frameworks remain rooted in static…
Unlike many physical nonequilibrium systems, in biological systems, the coupling to external energy sources is not a fixed parameter but adaptively controlled by the system itself. We do not have theoretical frameworks that allow for such…
Integrated population models (IPMs) are a promising approach to test ecological theories and assess wildlife populations in dynamic and uncertain conditions. By combining multiple data sources into a unified model, they enable the…
We present an asymptotic analysis of a stochastic two-compartmental cell division system with regulatory mechanisms inspired by Getto et al. (2013). The hematopoietic system is modeled as a two-compartment system, where the first…
The human niche represents the intersection of biological, ecological, cultural, and technological processes that have co-evolved to shape human adaptation and societal complexity. This paper explores the human niche through the lens of…
Tuberculosis (TB) continues to pose a major public health challenge, particularly in high-burden regions such as Ethiopia, necessitating a more profound understanding of its transmission dynamics. In this study, we developed an SVEITRS…