其他定量生物学
The proton-magnetic reaction is commonly used in MRI machines with a strong magnetic field of over 1 T, while this study hypothesized that the electron magnetic reaction of hydrogen could affect the hydrogen bonds of double-stranded DNA…
Virtual patients and digital patients/twins are two similar concepts gaining increasing attention in health care with goals to accelerate drug development and improve patients' survival, but with their own limitations. Although methods have…
Computing in the life sciences has undergone a transformative evolution, from early computational models in the 1950s to the applications of artificial intelligence (AI) and machine learning (ML) seen today. This paper highlights key…
In this manuscript we will present a brief overview of the comorbidity concept. We will start by laying its foundations and its definitions and then describing the role that machine learning can hold in mining and defining it. The purpose…
On December 15, 2023, The National Academies of Sciences, Engineering and Medicine (NASEM) released a report entitled: Foundational Research Gaps and Future Directions for Digital Twins. The ostensible purpose of this report was to bring…
This study proposes an innovative approach to analyze spatial patterns of behavior by integrating information in weighted Voronoi diagrams. The objective of the research is to analyze the temporal distribution of an experimental subject in…
The year 2023 marked a significant surge in the exploration of applying large language model (LLM) chatbots, notably ChatGPT, across various disciplines. We surveyed the applications of ChatGPT in bioinformatics and biomedical informatics…
Assembly Theory (AT) was developed to help distinguish living from non-living systems. The theory is simple as it posits that the amount of selection or Assembly is a function of the number of complex objects where their complexity can be…
Single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to analyze gene expression at the resolution of individual cells, providing unprecedented insights into cellular heterogeneity and complex biological systems. This paper…
One of the most effective ways to treat liver cancer is to perform precise liver resection surgery, the key step of which includes precise digital image segmentation of the liver and its tumor. However, traditional liver parenchymal…
Individual human recognition is important for species that live in close proximity to humans. Numerous studies on domesticated species and urban-adapted birds have highlighted this ability. One such species which is heavily reliant on…
Biodiversity data are substantially increasing, spurred by technological advances and community (citizen) science initiatives. To integrate data is, likewise, becoming more commonplace. Open science promotes open sharing and data usage.…
Non-coding RNA are functional molecules that are not translated into proteins. Their function comes as important regulators of biological function. Because they are not translated, they need not be as stable as other types of RNA. The TKF91…
We examine a series of articles on honeybee odometry and navigation published between 1996 and 2010, and find inconsistencies in results, duplicated figures, indications of data manipulation, and incorrect calculations. This suggests that…
Diabetes is a chronic condition, considered one of the civilization diseases, that is characterized by sustained high blood sugar levels. There is no doubt that more and more people is going to suffer from diabetes, hence it is crucial to…
Heterogeneous, interconnected, systems-level, molecular data have become increasingly available and key in precision medicine. We need to utilize them to better stratify patients into risk groups, discover new biomarkers and targets,…
The aqueous extract of Salix spp contains many compounds which may act as root-promoting agents in cuttings. S. alba is a deciduous tree containing variable phytochemicals which are variable throughout the year. So, in this study, one- and…
Arbovirus is a vital, life-threatening disease worldwide and continues to be a significant problem while the world is dealing with the major coronavirus (COVID-19) pandemic. Vectors, mostly mosquitoes and ticks, transmit this disease.…
One of the most fundamental rules in metabolic ecology is the allometric equation, which is a power-law scaling that describes the connection between body measurements and body size. The biological dynamics of this essentially empirical…
Many sexually mature women experience premenstrual syndrome (PMS) or premenstrual dysphoric mood disorder (PMDD). Current approaches for managing PMS and PMDD rely on daily mental condition recording, which many discontinue due to its…