医学物理
Intraoperative optical imaging is essential for surgical precision and patient safety, but current systems present anatomical and fluorescence information separately, causing delays and increasing cognitive load. A unified system for…
Minibeam and microbeam radiation therapy promise improved treatment outcomes through reduced normal tissue toxicity at better tumor control rates. The lack of suitable compact radiation sources limits the clinical application of minibeams…
We propose a noninvasive and dispersive framework for estimating the spatially nonuniform conductivity of brain tumors using MR images. The method consists of two components: (i) voxel-wise assignment of tumor conductivity based on…
This work presents a systematic design of a metasurface-based microwave hyperthermia system, leveraging the time-reversal technique to achieve precise focusing of electromagnetic energy at deep-seated brain tumors. The manuscript includes…
Computational cardiovascular models are promising tools for clinical decision support, particularly in complex conditions, such as intraoperative hypotension (IOH). IOH arises from different mechanisms, making treatment selection…
Purpose: The expansion of radiopharmaceutical therapy (RPT) development demands scalable preclinical dosimetry methods. While PET and SPECT remain the gold standards, their low throughput and high cost limit large-cohort studies. Cherenkov…
Passive resonators have been widely used in MRI to manipulate RF field distributions. However, optimizing these structures using full-wave electromagnetic simulations is computationally prohibitive, particularly for large passive resonator…
Background: The emergence and growth of fusion technology enables investigative studies into its applications beyond typical power production facilities. This study seeks to determine the viability of medical isotope production with the…
Purpose: Artificial intelligence (AI) techniques have been extensively utilized for diagnosing and prognosis of several diseases in recent years. This study identifies, appraises and synthesizes published studies on the use of AI for the…
The COVID-19 pandemic has placed unprecedented strain on healthcare systems and remains a global health concern, especially with the emergence of new variants. Although real-time polymerase chain reaction (RT-PCR) is considered the gold…
Radioactive ion beams (RIB) are a key focus of current research in nuclear physics. Already long ago it was proposed that they could have applications in cancer therapy. In fact, while charged particle therapy is potentially the most…
Magnetic resonance imaging (MRI) is the gold standard imaging modality for numerous diagnostic tasks, yet its usefulness is tempered due to its high cost and infrastructural requirements. Low-cost very-low-field portable scanners offer new…
Magnetic Resonance Elastography (MRE) noninvasively maps brain biomechanics and is highly sensitive to alterations associated with aging and neurodegenerative disease. Most implementations use a single frequency or a narrow frequency band,…
A major challenge in diagnosing and treating cancer is the infiltrative growth of tumors into surrounding tissues. This microscopic spread of the disease is invisible on most diagnostic imaging modalities and can often only be detected…
In this work, the effect of the measurement position on measurements of $H_\text{p}(3)$ of a new active eye lens dosemeter prototype based on the Dosepix detector is examined. A comparison between measuring directly in front of the eye and…
Temporary plastic film barriers are widely used to separate occupied rooms from exterior renovation zones, yet their effect on indoor particulate exposure is poorly quantified. We monitored PM$_{2.5}$ in a Tampa, Florida, apartment for 48…
This study evaluated whether AutoSense Sky OS, an automatic classifier used in pediatric Advanced Bionics cochlear implants (CIs), improves speech intelligibility from the front without significantly impairing spatial awareness (i.e., sound…
Purpose: To develop and validate a framework for rapid, accurate, and reproducible whole-brain, multi-pool chemical exchange saturation transfer (CEST) imaging at 3T, addressing challenges of long acquisition times and confounding factors.…
The propagation of minibeams of protons and $^{12}$C in a water phantom was modelled with Geant4 v10.3, and the survival probabilities of human salivary gland cells representing healthy and tumour tissues of normal radiosensitivity were…
Portable, low-field Magnetic Resonance Imaging (MRI) scanners are increasingly being deployed in clinical settings. However, key barriers to their widespread use include low signal-to-noise ratio (SNR), generally low image quality, and long…