医学物理
Herein we report the first in-human transcranial imaging of brain function using photoacoustic computed tomography. Functional responses to benchmark motor tasks were imaged on both the skull-less and the skull-intact hemispheres of a…
Optical-resolution photoacoustic microscopy has been validated as a high-resolution and high-sensitivity imaging modality for angiographic studies in the past decades. Quantitative vascular analysis reveals critical information of…
T2-Shuffling reconstructs multiple sharp T2-weighted images from a single volumetric fast spin-echo (3D-FSE) scan. Wave-CAIPI is a parallel imaging technique that achieves good reconstruction at high accelerations through additional…
Tumor segmentation in oncological PET is challenging, a major reason being the partial-volume effects that arise due to low system resolution and finite voxel size. The latter results in tissue-fraction effects, i.e. voxels contain a…
Primordial radionuclides such as uranium (U-238), thorium (Th-232), and potassium (K-40) and their progenies contained in coal can be a source of concern to the environment in a thermal coal-powered plant. In this study, the average…
Background and purpose: The relative biological effectiveness (RBE) varies along the treatment field. However, in clinical practice, a constant RBE of 1.1 is assumed, which can result in undesirable side effects. This study provides an…
High impedance RF coils, such as self-decoupled coils, reduce the electromagnetic coupling between the coil elements and eliminates the use of complex decoupling technologies. Although the high impedance design promises excellent decoupling…
Microstrip lines are being used in MR applications due to their unique properties, such as reduced radiation loss, high-frequency capability, and reduced perturbation of sample loading to the RF coil compared to conventional coils. Here, we…
Arterial pulse waves contain clinically useful information: their intensity varies with cardiac performance, their speed (pulse wave velocity; PWV) depends on arterial stiffness and their reflection is affected by conduit artery tone. Here…
Purpose: Real time monitoring of dynamic magnetic fields has recently become a commercially available option for measuring MRI k-space trajectories and magnetic fields induced by eddy currents in real time. However, for accurate image…
Combining the unmatched soft-tissue imaging capabilities of magnetic resonance imaging (MRI) with high precision robotics has the potential to improve the accuracy, precision, and safety of a wide range of image-guided medical procedures.…
The electrical property (EP) of human tissues is a quantitative biomarker that facilitates early diagnosis of cancerous tissues. Magnetic resonance electrical properties tomography (MREPT) is an imaging modality that reconstructs EPs by the…
Accurate estimates of left ventricle elastances based on non-invasive measurements are required for clinical decision-making during treatment of valvular diseases. The present study proposes a parameter discovery approach based on a lumped…
Magnetic Particle Imaging (MPI) is a novel and versatile imaging modality developing towards human application. When up-scaling to human size, the sensitivity of the systems naturally drops as the coil sensitivity depends on the bore…
Real-time monitoring of the gastrointestinal tract in a safe and comfortable manner is valuable for the diagnosis and therapy of many diseases. Within this realm, our review captures the trends in ingestible capsule systems with a focus on…
The following paper describes a method for three-dimensional (3D) reconstruction of multi-material objects based on propagation-based X-ray phase-contrast tomography (PB-CT) with phase retrieval using the homogenous form of the…
The inclusion of small amounts of copper is often reported to enhance the mechanical and biointegrative performance of bioceramics towards tissue engineering applications. In this work, 3D scaffolds were additively manufactured by…
Cone-beam CT (CBCT) is installed in the treatment room to facilitate online clinical applications, including image guidance in radiation and surgery. Half-fan and short-can are the commonly used modes in clinical applications to expand the…
Magnetoencephalography (MEG) is a noninvasive method for measuring magnetic flux signals caused by brain activity using sensor arrays located on or above the scalp. A common strategy for monitoring brain activity is to place sensors on a…
Complete time of flight (TOF) sinograms of state-of-the-art TOF PET scanners have a large memory footprint. Currently, they contain ~4e9 data bins which amount to ~17GB in 32bit floating point precision. Using iterative algorithms to…