医学物理
Measurement of intramuscular oxygen could play a key role in the early diagnosis of acute compartment syndrome, a common condition occurring after severe trauma leading to ischemia and long-term consequences including rhabdomyolysis, limb…
Background: While increasing the ventilation rate is an important measure to remove inhalable virus-laden respiratory particles and lower the risk of infection, direct validation in schools with population-based studies is far from…
A standard dose of radioactive tracer must be delivered into the patients body to obtain high-quality Positron Emission Tomography (PET) images for diagnostic purposes, which raises the risk of radiation harm. A reduced tracer dose, on the…
We enable the estimation of the per-axon axial diffusivity from single encoding, strongly diffusion-weighted, pulsed gradient spin echo data. Additionally, we improve the estimation of the per-axon radial diffusivity compared to estimates…
Organized by Working Group 6 "Computational Dosimetry" of the European Radiation Dosimetry Group (EURADOS), a group of intercomparison exercises was conducted in which participants were asked to solve predefined problems in computational…
Anisotropic X-ray Dark-field Tomography (AXDT) is a recently developed imaging modality that enables the visualization of oriented microstructures using lab-based X-ray grating interferometer setups. While there are very promising…
CEST suffers from two main problems long acquisitin times or restricted coverage as well as incoherent protocol settings. In this paper we give suggestions on how to optimise your protocol settings fro CEST and present one setting for APT…
We consider an optimal flow control problem in a patient-specific coronary artery bypass graft with the aim of matching the blood flow velocity with given measurements as the Reynolds number varies in a physiological range. Blood flow is…
Advanced ultrasound computed tomography techniques like full-waveform inversion are mathematically challenging and orders of magnitude more computationally expensive than conventional ultrasound imaging methods. This computational and…
Attenuation and scatter correction (AC) is crucial for quantitative Positron Emission Tomography (PET) imaging. Recently, direct application of AC in the image domain using deep learning approaches has been proposed for the hybrid PET/MR…
Purpose: Diffusion MRI (dMRI) suffers from eddy currents induced by strong diffusion gradients, which introduce artefacts that can impair subsequent diffusion metric analysis. Existing retrospective correction techniques that correct for…
Quantitative susceptibility mapping (QSM) is a MRI technique that estimates tissue magnetic susceptibility. The generation of QSM requires solving a challenging ill-posed field-to-source inversion problem. Recently, several deep learning…
Proton therapy systems without a gantry can be more compact and less expensive in terms of capital cost, and therefore more available to a larger patient population. Would the advances in pencil beam scanning and robotics make gantry-less…
Background and Objective: Recent experimental studies using ultra-high dose rate radiation therapy (FLASH-RT) have shown improved normal tissue sparing and comparable tumor control compared to conventional dose rate RT. Pencil beam scanning…
Background. Absorbed radiation dose to the mandible is an important risk factor in the development of mandibular osteoradionecrosis (ORN) in head and neck cancer (HNC) patients treated with radiotherapy (RT). The prediction of mandibular…
In this paper, a simple theoretical model of excitation of action potentials of multiple motor pools by stimulating current pulses over the lumbosacral regions of the spinal cord is presented. The present model is consistent with known…
Ultrasound computed tomography (USCT) is an emerging imaging modality for breast imaging that can produce quantitative images that depict the acoustic properties of tissues. Computer-simulation studies, also known as virtual imaging trials,…
We test the feasibility of calculating proton stopping power (SP) from a set of virtual monochromatic (VM) CT images, created with Monte Carlo-generated CT scans, using a dual-energy CT-to-SP procedure. The Monte Carlo CT simulations, with…
For minimally invasive endovascular surgery, the localization of catheters and guidewires inside the human body is essential. Electromagnetic (EM) tracking is one technology that allows localizing such surgical instruments. For localizing…
The high cost and low image quality traditionally associated with proton computed tomography (pCT) have prevented it from seeing significant use in clinical settings. A cheap, compact, high-density scintillating glass detector capable of…