医学物理
Chronic Obstructive Pulmonary Disease (COPD) is a progressive lung disease characterized by airflow limitation. This study develops a systems engineering framework for representing important mechanistic details of COPD in a model of the…
The varied radiological applications of tissue equivalent (TE) materials encompass quality checks, diagnostic imaging and dose evaluations. Nevertheless, the availability of compounds representative of paediatric patient tissues for…
Cerebral aneurysm progression is a result of a complex interplay of the biomechanical and clinical risk factors that drive aneurysmal growth and rupture. Subjects with multiple aneurysms are unique cases wherein clinical risk factors are…
Estimating magnetic susceptibility using MRI depends on inverting a forward relationship between the susceptibility and measured Larmor frequency. However, an often-overlooked constraint in susceptibility fitting is that the Larmor…
Since decades, many techniques have been developed for curing cancer. Here, an effort has been made to cure tumor by inserting a cryoprobe into the target region which is connected to a cryogenic mechanism. This technique is presently used…
Dose verification based on proton-induced positron emitters is a promising quality assurance tool and may leverage the strength of artificial intelligence. To move a step closer towards practical application, the sensitivity analysis of two…
This Special Report summarizes the 2022 AAPM Grand Challenge on Deep-Learning spectral Computed Tomography (DL-spectral CT) image reconstruction. The purpose of the challenge is to develop the most accurate image reconstruction algorithm…
Ultrafast imaging modes, such as coherent plane-wave compounding (CPWC), capture a large field of view in a single pulse-echo measurement using parallel receive focusing. The number of foci or, equivalently, the number of volume elements…
Magnesium (Mg) and its alloys have attracted considerable attention owing to their excellent biodegradable properties and biocompatibility. Novel Mg-Sn-Ge ternary Mg alloys were developed as potential biodegradable materials for orthopedic…
FLASH is a new treatment modality that requires optimization of dose, dose rate, and LET. Here we validate these three quantities under FLASH conditions, which includes the quantum uncertainty in the time-dependent instantaneous dose rate…
The advanced imaging and delivery techniques in proton therapy allow conformal high-dose irradiation of the target volume with high accuracy using pencil beam scanning or beam shaping apertures. These irradiation methods increasingly…
Particle therapy is an established method to treat deep-seated tumours using accelerator-produced ion beams. For treatment planning, the precise knowledge of the relative stopping power (RSP) within the patient is vital. Conversion errors…
Adaptive Radiotherapy (ART) is an emerging technique for treating cancer patients which facilitates higher delivery accuracy and has the potential to reduce toxicity. However, ART is also resource-intensive, requiring extra human and…
Purpose: Target delineation for radiation therapy is a time-consuming and complex task. Autocontouring gross tumor volumes (GTVs) has been shown to increase efficiency. However, there is limited literature on post-operative target…
In the first step, a pre-trained model (YOLO) was used to detect all suspicious nod-ules. The YOLO model was re-trained using 397 CT images to detect the entire nodule in CT images. To maximize the sensitivity of the model, a confidence…
Quantitative image reconstruction in dual-energy computed tomography (CT) remains a topic of active research. We read with interest ``DIRECT-Net: A unified mutual-domain material decomposition network for quantitative dual-energy CT…
The access to activity of subcortical structures offers unique opportunity for building intention dependent brain-computer interfaces, renders abundant options for exploring a broad range of cognitive phenomena in the realm of affective…
The field of cardiac electrophysiology tries to abstract, describe and finally model the electrical characteristics of a heartbeat. With recent advances in cardiac electrophysiology, models have become more powerful and descriptive as ever.…
Purpose: To develop and validate a phantom for diagnostic ultrasound (US) scanners by embedding targets in gel wax to determine the image uniformity, lateral and axial resolution, and diameter of a stainless-steel disc. Materials and…
Iterative least-squares MR reconstructions typically use the Conjugate Gradient algorithm, despite known numerical issues. This paper demonstrates that the more recent LSMR algorithm has favourable numerical properties, and is to be…