医学物理
Finite element analysis (FEA) can be used to evaluate applied interface pressures and internal tissue strains for computational prosthetic socket design. This type of framework requires realistic patient-specific limb geometry and…
Biophysical modelling of the diffusion MRI signal provides estimates of specific microstructural tissue properties. Although nonlinear optimization such as non-linear least squares (NLLS) is the most widespread method for model estimation,…
Phantom eye devices are designed to mimic the optical properties of the human eye; however, the retinal structures are typically emulated with synthetic tissues. Thus, it is currently impossible to exploit phantom eye devices for…
Microbubbles - used as contrast agents in ultrasound imaging - are important tools in biomedical research, having been used together with ultrasound to develop significant diagnostic and therapeutic techniques. It has been suggested that…
Charge accumulation was measured under calibration conditions in the spread-out Bragg peak (SOBP) using the calibration bias as well as a range of voltages from 10V to 500V and a Farmer-style ion chamber. Collection efficiency was…
Background: Direct dental restoration implies a drying of the dentin substrate. This drying may induce significant strain in the dentin, affecting the bonding efficiency of the restoration. Objective: We measure the dilatation of dentine…
Adaptive radiation therapy (ART) could protect organs at risk (OARs) while maintain high dose coverage to targets. However, there still lack efficient online patient QA methods. We aim to develop a clinically relevant online patient quality…
Computed ultrasound tomography in echo mode (CUTE) is a new ultrasound (US)-based medical imaging modality with promise for diagnosing various types of disease based on the tissue's speed of sound (SoS). It is developed for conventional…
Electromagnetic decoupling among a close-fitting or high-density transceiver RF array elements is required to maintain the integrity of the magnetic flux density from individual channel for enhanced performance in detection sensitivity and…
A permanent magnet array (PMA) is a preferred source of magnetic field for body-part-dedicated low-field (<0.5 T) portable magnetic resonance imaging (MRI) because it has a small footprint, no power consumption, and no need for a cooling…
Most ultrasound imaging techniques necessitate the fundamental step of converting temporal signals received from transducer elements into a spatial echogenecity map. This beamforming (BF) step requires the knowledge of speed-of-sound (SoS)…
Fast and accurate dose predictions are one of the bottlenecks in treatment planning for microbeam radiation therapy (MRT). In this paper, we propose a machine learning (ML) model based on a 3D U-Net. Our approach predicts separately the…
Muscle tissue drives nearly all movement in the animal kingdom, providing power, mobility, and dexterity. Technologies for measuring muscle tissue motion, such as sonomicrometry, fluoromicrometry, and ultrasound, have significantly advanced…
One of the greatest needs in modern ophthalmology is access to the eye choroid in vivo. Without it, it is difficult to introduce new therapies and to understand most of the pathological changes in the eye, because of the total blood flow in…
We are in a golden age of progress in artificial intelligence (AI). Radiotherapy, due to its technology-intensive nature as well as direct human-machine interactions, is perfectly suited for benefitting from AI to enhance accuracy and…
Joint tissues consist of trabecular and cortical bone as well as calcified and hyaline cartilage, which presents a challenge for hard X-ray-based visualization on the sub-cellular level due to the wide range of local X-ray absorption…
Purpose: To optimize the choice of the flip-angles of magnetization-prepared gradient echo (MP-GRE) sequences for improved accuracy, precision, and speed of 3D-T1rho mapping. Methods: We propose a new optimization approach for finding…
Objective: Organ deformation models have the potential to improve delivery and reduce toxicity of radiotherapy, but existing data-driven motion models are based on either patient-specific or population data. We propose to combine population…
Secondary radiation in a radiation therapy environment is considered a cause for post-treatment side effects including secondary carcinogenesis. In a proton-therapy setup, neutrons deliver a considerable extra dose to the patient. Various…
Purpose: The expanded encoding model incorporates spatially- and time-varying field perturbations for correction during reconstruction. So far, these reconstructions have used the conjugate gradient method with early stopping used as…