医学物理
Purpose: Field monitoring measures field perturbations, which can be accounted for during image reconstructions. In certain field monitoring environments, significant phase deviations can arise far from isocenter due to the finite extent of…
Biparametric MRI has emerged as an alternative to multiparametric prostate MRI, which eliminates the need for the potential harms to the patient due to the contrast medium. One major issue with biparametric MRI is difficulty to detect…
With the development of computed tomography (CT) imaging technology, it is possible to acquire multi-energy data by spectral CT. Being different from conventional CT, the X-ray energy spectrum of spectral CT is cutting into several narrow…
Background and purpose: In-beam Positron Emission Tomography (PET) is one of the modalities that can be used for in-vivo non-invasive treatment monitoring in proton therapy. PET distributions obtained during various treatment sessions can…
Imaging the human brain vasculature with high spatial and temporal resolution remains challenging in the clinic today. Transcranial ultrasound is scarcely used for cerebrovascular imaging, due to low sensitivity and strong phase aberrations…
Spatially fractionated radiation therapy (SFRT or GRID) is an approach to deliver high local radiation doses in an 'on-off' pattern. To better appraise the radiobiological effects from GRID, a framework to link local radiation dose to…
In this study we evaluated the task-based image quality of a low contrast clinical task for the abdomen protocol (e.g., pancreatic tumour) of three different CT vendors, exploiting three model-based iterative reconstruction (MBIR) levels.…
Recently, a new bi-layer dressing was proposed by Urgo RID to reduce the healing time of pressure ulcers (PU). This dressing was numerically evaluated in previously published work. In the current work, the influence on the maximal shear…
Advances in instrumentation and tracer materials are still required to enable sensitive and accurate 3D temperature monitoring by magnetic particle imaging. We have developed a magnetic particle imaging instrument to observe temperature…
Thermal ablation procedures, such as high intensity focused ultrasound (HIFU) and Radiofrequency Ablation (RFA), are often used to eliminate tumors by minimally invasively heating a focal region. For this task, real-time 3D temperature…
The use of adjoint solvers is considered in order to obtain the sensitivity of clinical measures in aneurysms to incomplete (or unknown) boundary conditions and/or geometry. It is shown that these techniques offer interesting theoretical…
In the context of continued spread of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 and the emergence of new variants, the demand for rapid, accurate, and frequent detection is increasing. Besides, the new predominant strain,…
Objectives: To develop a joint k-TE reconstruction algorithm to reconstruct the T2-weighted (T2W) images and T2 map simultaneously. Materials and Methods: The joint k-TE reconstruction model was formulated as an optimization problem subject…
Imaging distributions of radioactive sources plays a substantial role in nuclear medicine as well as in monitoring nuclear waste and its deposit. Coded Aperture Imaging has been proposed as an alternative to parallel or pinhole collimators,…
Low-count reconstruction remains a challenge for Positron Emission Tomography (PET) even with the recent progress in time-of-flight (TOF) resolution. In this context, the bias between the acquired histogram, consisting of low values or…
A fundamental, Quantum Mechanical description of photoactivation of a generic photosensitizer and the ensuing transfer of energy to endogenous oxygen as part of the Type II pathway to photodamage during photodynamic therapy (PDT) is…
We investigated the possibility of augmenting the fluence of electrons traversing CdTe thin film and thus increasing the detected signal pursuing two venues: adding a high-Z metal layer to the back of the detector surface, and adding a top…
Methods: A phase space file in a plane at 202 mm downstream of the beam exit window is generated through tuning parameters to match FDC results with measured or MCNPX Monte Carlo-simulated integrated depth-dose distribution (IDD) and…
Purpose: To develop a radiomics filtering technique for characterizing spatial-encoded regional pulmonary ventilation information on lung CT. Methods: The lung volume was segmented on 46 CT images, and a 3D sliding window kernel was…
Purpose: To develop an efficient simultaneous multi-slab imaging method with blipped-controlled aliasing in parallel imaging (blipped-SMSlab) in a 4D k-space framework, and demonstrate its efficacy in high-resolution diffusion MRI (dMRI).…