医学物理
In the 21st century, biosensors have gathered much wider attention than ever before, irrespective of the technology that promises to bring them forward. With the recent COVID-19 outbreak, the concern and efforts to restore global health and…
In their article published in Phys. Med. Biol. 60 (2015) 4149-4168, Lin et al studied the radiosensitizing effect of gold nanoparticles (GNPs) using radiation transport simulations and a biological model for the survival of irradiated…
In their article published in Phys. Med. Biol. 59 (2014) 7675-7689, Lin et al studied the dose enhancement of of gold nanoparticles (GNPs) for proton therapy, which they compared with the case of photon irradiation. This comment points out…
Diffusion-weighted (DW) magnetic resonance spectroscopy (MRS) suffers from a lower signal to noise ratio (SNR) compared to conventional MRS owing to the addition of diffusion attenuation. This technique can therefore strongly benefit from…
Type C hepatic encephalopathy (HE) is a complex neuropsychiatric disorder occurring as a consequence of chronic liver disease. Alterations in energy metabolism have been suggested in type C HE, but $\textit{in vivo}$ studies on this matter…
In our work, a novel processing strategy for the continuous fabrication and surface modification of wires from Magnesium alloy WE43 by means of plasma-electrolytic oxidation (PEO) is presented. In the first step, wires with a strong basal…
We analyze the information that can be retrieved from the tracking parameters produced by an innovative wearable eye tracker. The latter is based on a permanent-magnet marked corneal lens and by an array of magnetoresistive detectors that…
The development of methods to safely rewarm large volume cryopreserved biological samples remains a barrier to the widespread adoption of cryopreservation. Here, experiments and simulations were performed to demonstrate that ultrasound can…
The global pandemic has significantly increased the demand for personal protective equipment (PPE). The antimicrobial coating has been broadly applied to PPE to improve its prevention capability, especially after prolonged usage. However,…
Photon-counting spectral computed tomography is now clinically available. These new detectors come with the promise of higher contrast-to-noise ratio and spatial resolution and improved low-dose imaging. However, one important design…
With the proliferation of inexpensive CMOS cameras, medical imaging experiences a noticeable influx of new technologies. While anatomical imaging is based on well-established principles of photography, physiological optical imaging is a…
First investigations regarding dosimetric properties of the hybrid, pixelated, photon-counting Dosepix detector in the direct beam of a pulsed photon field (RQR8) for the personal dose equivalent $H\mathrm{_p(10)}$ are presented. The…
This paper presents the mathematical modeling-based design and simulation of normal mode MEMS capacitive pressure sensor for blood pressure sensing application. The normal blood pressure of human being is 120/80 mmHg. But this range varies…
Purpose: We address the challenge of inaccurate parameter estimation in diffusion MRI when the signal-to-noise ratio (SNR) is very low, as in the spinal cord. The accuracy of conventional maximum-likelihood estimation (MLE) depends highly…
Purpose: Volumetric, high-resolution, quantitative mapping of brain tissue relaxation properties is hindered by long acquisition times and signal-to-noise (SNR) challenges. This study, for the first time, combines the time-efficient…
This work aims to investigate the accuracy of quantitative SPECT imaging of $^{177}$Lu in the presence of $^{90}$Y, which occurs in dual-isotope radiopharmaceutical therapy (RPT) involving both isotopes. We used the GATE Monte Carlo…
Background: Individual skull models of bone density and geometry are important when planning the expected transcranial ultrasound acoustic field and estimating mechanical and thermal safety in low-intensity transcranial ultrasound…
Purpose. To demonstrate accurate measurement of corneal elastic moduli in vivo with non-contact and non-invasive optical coherence elastography. Methods. Elastic properties (in-plane Young's modulus E and both in-plane, u, and out-of-plane,…
Recently, shoot-through proton FLASH has been proposed where the highest energy is extracted from the cyclotron to maximize the dose rate (DR). Even though our proton pencil beam scanning system can deliver 250 MeV (the highest energy), it…
We present a novel thermodynamic parameter estimation framework for energy-based surgery on live tissue, with direct applications to tissue characterization during electrosurgery. This framework addresses the problem of estimating…