医学物理
Magnetic resonance imaging (MRI) is increasingly utilized for image-guided radiotherapy due to its outstanding soft-tissue contrast and lack of ionizing radiation. However, geometric distortions caused by gradient nonlinearity (GNL) limit…
Purpose: In this modelling study we pursued two main goals. The first was to establish a new CTV-to-PTV expansion which considers the closest and most critical organ at risk (OAR). The second goal was to investigate the impact of the…
Summary mean DCE-MRI variables show a clear dependency between signal and noise variance, which can be shown to reduce the effectiveness of difference assessments. Appropriate transformation of these variables supports statistically…
The goal of this work is to showcase the clinical value that portable MRI can provide in crowded events and major sports competitions. We temporarily installed a low-field and low-cost portable MRI system for extremity imaging in the…
Purpose: A promising approach to enable FLASH conformal proton therapy is to passively degrade a single energy layer using a patient-specific range modulator. We propose an innovative method to directly optimize the geometrical…
Validation of deformable image registration techniques is extremely important, but hard, especially when complex deformations or content mismatch are involved. These complex deformations and content mismatch, for example, occur after the…
Multi-parametric mapping of MRI relaxations in liver has the potential of revealing pathological information of the liver. A self-supervised learning based multi-parametric mapping method is proposed to map T$T_{1\rho}$ and T$_2$…
Objective: The main goal of the athletes who undergo anterior cruciate ligament reconstruction (ACLR) surgery is a successful return-to-sport. At this stage, identifying muscular deficits becomes important. Hence, in this study, three…
Dried blood spot (DBS) has risen in popularity due to the ease of sampling, storing, shipping and more. Despite those advantages, recovery of the dried blood in solution for analysis is still a bottleneck as it is manual, time-consuming and…
Objective: Strain elastography and shear wave elastography are two commonly used methods to quantify cervical elasticity; however, they have limitations. Strain elastography is effective in showing tissue elasticity distribution in a single…
Purpose: Task-based assessment of image quality in undersampled magnetic resonance imaging provides a way of evaluating the impact of regularization on task performance. In this work, we evaluated the effect of total variation (TV) and…
This report describes a set of neonatal electroencephalogram (EEG) recordings graded according to the severity of abnormalities in the background pattern. The dataset consists of 169 hours of multichannel EEG from 53 neonates recorded in a…
Breast-conserving surgery is the most acceptable operation for breast cancer removal from an invasive and psychological point of view. Before the surgical procedure, a preoperative MRI is performed in the prone configuration, while the…
Objective: Intensity-modulated radiation therapy (IMRT) beam angle optimization (BAO) is a challenging combinatorial optimization problem that is NP-hard. In this study, we aim to develop a personalized BAO algorithm for IMRT that improves…
In dual-energy computed tomography (DECT), the X-ray tube energy pair often changes depending on the target organ or patient obesity. In practice, it makes difficult to apply deep learning (DL) based algorithms for image reconstruction…
Robustness of Deep Neural Networks (DNNs) is an important aspect to consider for their clinical applications. This work examined robustness issue for a DNN-based multi-class classification model via comprehensive experimental and simulation…
We present a Machine Learning (ML) study case to illustrate the challenges of clinical translation for a real-time AI-empowered echocardiography system with data of ICU patients in LMICs. Such ML case study includes data preparation,…
Histological staining is the gold standard for tissue examination in clinical pathology and life-science research, which visualizes the tissue and cellular structures using chromatic dyes or fluorescence labels to aid the microscopic…
The advent of scalp magnetoencephalography (MEG) based on optically pumped magnetometers (OPMs) may represent a step change in the field of human electrophysiology. Compared to cryogenic MEG based on superconducting quantum interference…
Lowering the radiation dose in computed tomography (CT) can greatly reduce the potential risk to public health. However, the reconstructed images from the dose-reduced CT or low-dose CT (LDCT) suffer from severe noise, compromising the…